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Ticlopidine: History & Applications

Ticlopidine, sold under the brand name Ticlid, is a medication used to reduce the risk of thrombotic strokes. It is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor. Research initially showed that it was useful for preventing strokes and coronary stent occlusions. However, because of its rare…

Language: English [EN]
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Ticlopidine topic overview

The analysis highlights History and Applications as prominent areas in the source structure around Ticlopidine.

Related topics
14
Source areas
4
Connected nodes
18
Extracted relationships
84
Related term clusters
8
Bridge connections
18

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 7 topics
History · 4 topics
Mechanism of action · 2 topics
Medical uses · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
B01AC05 (WHO)
Bioavailability
>80%
CAS Number
55142-85-3 Y
ChEBI
CHEBI:9588 Y

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Mechanism of action

History

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Ticlopidine connects Entity context

The extracted context around Ticlopidine shows recurring relationship patterns in the source. For example, Ticlopidine → Apotex, April, Caraco, Castaigne, Castaigne SA, FDA, Fernand Eloy, France, Jean-Pierre Maffrand, Major, Par, Pharmacology, Roche, Sandoz, Sanofi, Starting, Syntex, Teva, Ticlid, US Another extracted example is Ticlopidine → ADP, Anti-platelet, P2Y12, Therefore, Ticlopidine’s, Without ADP. Use these groups to spot repeated connection types before inspecting the individual relationships.

Ticlopidine

Top relations

related to history · 20
Ticlopidine → Apotex, April, Caraco, Castaigne, Castaigne SA, FDA, Fernand Eloy, France, Jean-Pierre Maffrand, Major, Par, Pharmacology, Roche, Sandoz, Sanofi, Starting, Syntex, Teva, Ticlid, US
related to Mechanism of action · 6
Ticlopidine → ADP, Anti-platelet, P2Y12, Therefore, Ticlopidine’s, Without ADP
related to Interactions · 4
Ticlopidine → CYP2B6, CYP2C19, NSAIDs, Taking
Legal status · 3
Ticlopidine → EU: Rx-only, In general: ℞ (Prescription only), US: ℞-only
related to Heart disease · 3
Ticlopidine → Current, FDA, Therefore
related to Research · 3
Ticlopidine → Due, FDA, Soon
KEGG · 2
Ticlopidine → as HCl: D01028, D08594 Y
related to Contraindications · 2
Ticlopidine → History, Increased
related to Hematological · 2
Ticlopidine → TMA, Use
related to Pharmacokinetics · 2
Ticlopidine → Clearance, Even

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

effects drug strokes use studies blood risk side patients aspirin thrombotic antiplatelet liver days name medication serious approved disease ticlid

Ticlopidine relationships Subject–Predicate–Object triples

TTTA extracted 84 structured relationships around Ticlopidine. Examples in this analysis include Ticlopidine → 3D model (JSmol) → Interactive image and Ticlopidine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Ticlopidine3D model (JSmol)Interactive image1.00infobox
TiclopidineAHFS/Drugs.comMonograph1.00infobox
TiclopidineATC codeB01AC05 (WHO)1.00infobox
TiclopidineBioavailability>80%1.00infobox
TiclopidineCAS Number55142-85-3 Y1.00infobox
TiclopidineChEBICHEBI:9588 Y1.00infobox
TiclopidineChEMBLChEMBL833 Y1.00infobox
TiclopidineChemSpider5273 Y1.00infobox
TiclopidineCompTox Dashboard (EPA)DTXSID50236691.00infobox
TiclopidineDrugBankDB00208 Y1.00infobox
TiclopidineECHA InfoCard100.054.0711.00infobox
TiclopidineElimination half-life12 hours (single dose) 4–5 days (repeated dosing)1.00infobox
TiclopidineExcretionKidney and fecal1.00infobox
TiclopidineFormulaC14H14ClNS1.00infobox
TiclopidineIUPHAR/BPS73071.00infobox
TiclopidineKEGGD08594 Y1.00infobox
TiclopidineKEGGas HCl: D010281.00infobox
TiclopidineLegal statusUS: ℞-only1.00infobox
TiclopidineLegal statusEU: Rx-only1.00infobox
TiclopidineLegal statusIn general: ℞ (Prescription only)1.00infobox
TiclopidineLicense dataUS DailyMed: Ticlopidine1.00infobox
TiclopidineMedlinePlusa6950361.00infobox
TiclopidineMetabolismLiver1.00infobox
TiclopidineMolar mass263.78 g·mol−11.00infobox
TiclopidinePregnancy categoryAU: B11.00infobox
TiclopidineProtein binding98%1.00infobox
TiclopidinePubChem CID54721.00infobox
TiclopidineRoutes of administrationBy mouth1.00infobox
TiclopidineTrade namesTiclid1.00infobox
TiclopidineUNIIOM90ZUW7M11.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Ticlopidine bring nearby vocabulary together. In this analysis, examples include Blood, Effects and Liver. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Ticlopidine
    • Blood
    • Effects
    • Liver
    • Risk
    • Us
    • Approved
    • Associated
    • Disease
    • Fda
    • Days
    • Thrombotic
    • Patients
  • ticlopidine
    • Blood
    • Effects
    • Liver
    • Risk
    • Us
    • Approved
    • Associated
    • Disease
    • Fda
    • Days
    • Thrombotic
    • Patients
  • medication
    • Days
    • Risk
    • Thienopyridine
    • Used
    • Clopidogrel
    • Ticlid
    • Ticlopidine
    • Disease
    • Name
    • New
    • Platelet
    • Platelets
  • medical uses
    • Pregnancy
    • Research
    • Dosing
    • Heart
    • Repeated
    • Stent
    • Ticlid
    • Us
    • Disease
    • Name
    • New
    • Days
  • thrombotic microangiopathy
    • Used
    • Strokes
    • Ticlid
    • Patients
    • Heart
    • Antiplatelet
    • Associated
    • Disease
    • Serious
    • Ticlopidine
    • Aspirin
    • Side
  • clopidogrel
    • Use
    • Drugs
    • Thienopyridine
    • Disease
    • Medication
    • Serious
    • Days
    • Liver
    • Risk
    • Patients
    • Side
    • Drug
  • adp receptor
    • Platelets
    • Thienopyridine
    • Antiplatelet
    • Platelet
    • Drug
    • Ticlopidine
  • thienopyridine
    • Use
    • Ticlopidine

Connections between topic areas Semantic bridges

For Ticlopidine, one of the stronger structural bridges in this analysis connects Ticlopidine with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Ticlopidine — Overview · splits 11 ⟂ 8
Ticlopidine — History · splits 14 ⟂ 5
Ticlopidine — Mechanism of action · splits 16 ⟂ 3

Map overview Semantic statistics

Ticlopidine

Nodes19
Edges18
Triples84
Avg. degree1.89
Density0.105263
Components1

Source & methodology

TTTA analyzes the structure around Ticlopidine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Ticlopidine · EN edition · Analysis: TopicsToTalkAbout

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