Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Edoxaban

Edoxaban, sold under the brand name Lixiana among others, is an anticoagulant medication and a direct factor Xa inhibitor. It is taken by mouth.

Applications, Contraindications and notes & Pharmacokinetics

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Edoxaban. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
B01AF03 (WHO)
Bioavailability
62%; Tmax 1–2 hours
CAS Number
480449-70-5 N
ChEBI
CHEBI:85973 N

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications and notes

Adverse effects

Overdose

Mechanism of action

Pharmacokinetics

Comparison to other anticoagulants

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Edoxaban

Nodes93
Edges92
Triples65
Avg. degree1.98
Density0.021505
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Edoxaban

Top relations

related to Pharmacokinetics · 7
Edoxaban → CES1, CYP3A4, CYP3A5, Glucuronidation, In, Metabolism, With
related to Mechanism of action · 6
Edoxaban → In, Ki, Prothrombinases, Thrombins, Va, Xa
related to Overdose · 6
Edoxaban → Andexanet, April, EMA, FDA, Hemodialysis, No
related to Generic availability · 5
Edoxaban → British Columbia, Canada, In September, Sandoz Canada, Teva Canada
Legal status · 4
Edoxaban → CA: ℞-only, EU: Rx-only, In general: ℞ (Prescription only), US: ℞-only
related to Medical uses · 4
Edoxaban → European Union, In, It, United States
related to Comparison to other anticoagulants · 3
Edoxaban → In, INR, The
has effect · 2
Edoxaban → Health Canada, May
3D model (JSmol) · 1
Edoxaban → Interactive image
AHFS/Drugs.com · 1
Edoxaban → Monograph

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

approved blood anticoagulant anticoagulants embolism bleeding factor also use warfarin urine overdose mouth administration ces1 cyp3a4 hydrolysis risk people may

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Edoxaban3D model (JSmol)Interactive image1.00infobox
EdoxabanAHFS/Drugs.comMonograph1.00infobox
EdoxabanATC codeB01AF03 (WHO)1.00infobox
EdoxabanBioavailability62%; Tmax 1–2 hours1.00infobox
EdoxabanCAS Number480449-70-5 N1.00infobox
EdoxabanChEBICHEBI:85973 N1.00infobox
EdoxabanChemSpider8456212 N1.00infobox
EdoxabanCompTox Dashboard (EPA)DTXSID501973981.00infobox
EdoxabanDrugBankDB09075 N1.00infobox
EdoxabanElimination half-life10–14 hours1.00infobox
EdoxabanExcretion62% feces, 35% urine1.00infobox
EdoxabanFormulaC24H30ClN7O4S1.00infobox
EdoxabanIUPHAR/BPS75751.00infobox
EdoxabanKEGGD09710 N1.00infobox
EdoxabanLegal statusCA: ℞-only1.00infobox
EdoxabanLegal statusUS: ℞-only1.00infobox
EdoxabanLegal statusEU: Rx-only1.00infobox
EdoxabanLegal statusIn general: ℞ (Prescription only)1.00infobox
EdoxabanLicense dataUS DailyMed: Edoxaban1.00infobox
EdoxabanMedlinePlusa6140551.00infobox
EdoxabanMetabolismminimal CES1, CYP3A4/5, hydrolysis, glucuronidation1.00infobox
EdoxabanMolar mass548.06 g·mol−11.00infobox
EdoxabanOther namesDU-176b1.00infobox
EdoxabanProtein binding55%1.00infobox
EdoxabanPubChem CID102807351.00infobox
EdoxabanRoutes of administrationBy mouth1.00infobox
EdoxabanTrade namesSavaysa, Lixiana, Roteas, others1.00infobox
EdoxabanUNIINDU3J18APO1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.