Thrombomodulin

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Thrombomodulin topic overview

The analysis highlights Function, Genetics and structure and Interactions as prominent areas in the source structure around Thrombomodulin.

Related topics: 25
Source areas: 4
Connected nodes: 29
Extracted relationships: 102
Concept neighborhoods: 13
Bridge connections: 29

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 9 topics

Function · 8 topics

Genetics and structure · 7 topics

Interactions · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: THBD, AHUS6, BDCA3, CD141, THPH12, THRM, TM, thrombomodulin, BDCA-3
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ADX, 1DQB, 1DX5, 1EGT, 1FGD, 1FGE, 1HLT, 1TMR, 1ZAQ, 2ADX, 3GIS
Band: 20p11.21 · 2 G3|2 73.45 cM
Bgee: gingival epithelium · vena cava · right lung · skin of hip · skin of abdomen
BioGPS: More reference expression data
Chr.: Chromosome 20 (human) · Chromosome 2 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Genetics and structure

Function

Cofactor Cofactor (biochemistry)
Protein C
Anticoagulant
Thrombin-activatable fibrinolysis inhibitor Carboxypeptidase B2
Glycoprotein
C3b
Atypical hemolytic-uremic syndrome
Antigen

Interactions

Interact Protein-protein interaction

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Thrombomodulin connects Entity context

The extracted context around Thrombomodulin shows recurring relationship patterns in the source. For example, Thrombomodulin → apicolateral plasma membrane, blood coagulation, calcium ion binding, cell surface, extracellular space, female pregnancy, hemostasis, integral component of membrane, integral component of plasma membrane, leukocyte migration, membrane, negative regulation of blood coagulation, negative regulation of fibrinolysis, negative regulation of platelet activation, plasma membrane, protein binding, response to cAMP, response to lipopolysaccharide, response to X-ray, signal transduction Another extracted example is Thrombomodulin → ankle, aortic valve, ascending aorta, calvaria, decidua, gingival epithelium, Gonadal ridge, left coronary artery, left lung, left lung lobe, lower lobe of lung, periodontal fiber, right lung, right lung lobe, skin of abdomen, skin of hip, skin of thigh, upper lobe of left lung, vena cava, white adipose tissue. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 23

Thrombomodulin → apicolateral plasma membrane, blood coagulation, calcium ion binding, cell surface, extracellular space, female pregnancy, hemostasis, integral component of membrane, integral component of plasma membrane, leukocyte migration, membrane, negative regulation of blood coagulation, negative regulation of fibrinolysis, negative regulation of platelet activation, plasma membrane, protein binding, response to cAMP, response to lipopolysaccharide, response to X-ray, signal transduction

Bgee · 20

Thrombomodulin → ankle, aortic valve, ascending aorta, calvaria, decidua, gingival epithelium, Gonadal ridge, left coronary artery, left lung, left lung lobe, lower lobe of lung, periodontal fiber, right lung, right lung lobe, skin of abdomen, skin of hip, skin of thigh, upper lobe of left lung, vena cava, white adipose tissue

RNA expression pattern · 20

related to Genetics and structure · 8

Thrombomodulin → C-type, CTLD, EGF-like, In, It, Serine/Threonine-rich, THBD, The

related to Function · 7

Thrombomodulin → B2, C3b, Mutations, TAFI, THBD, This, Thrombomodulin-bound

Band · 2

Thrombomodulin → 2 G3|2 73.45 cM, 20p11.21

Chr. · 2

Thrombomodulin → Chromosome 2 (mouse), Chromosome 20 (human)

End · 2

Thrombomodulin → 148,250,108 bp, 23,049,672 bp

Aliases · 1

Thrombomodulin → THBD, AHUS6, BDCA3, CD141, THPH12, THRM, TM, thrombomodulin, BDCA-3

Available structures · 1

Thrombomodulin → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ADX, 1DQB, 1DX5, 1EGT, 1FGD, 1FGE, 1HLT, 1TMR, 1ZAQ, 2ADX, 3GIS

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human bp thrombin chr band gene protein thbd chromosome 20 expressed cells bdca-3 surface location function also membrane mouse cofactor

Thrombomodulin relationships Subject–Predicate–Object triples

TTTA extracted 102 structured relationships around Thrombomodulin. Examples in this analysis include Thrombomodulin → Aliases → THBD, AHUS6, BDCA3, CD141, THPH12, THRM, TM, thrombomodulin, BDCA-3 and Thrombomodulin → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ADX, 1DQB, 1DX5, 1EGT, 1FGD, 1FGE, 1HLT, 1TMR, 1ZAQ, 2ADX, 3GIS. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Thrombomodulin	Aliases	THBD, AHUS6, BDCA3, CD141, THPH12, THRM, TM, thrombomodulin, BDCA-3	1.00	infobox
Thrombomodulin	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ADX, 1DQB, 1DX5, 1EGT, 1FGD, 1FGE, 1HLT, 1TMR, 1ZAQ, 2ADX, 3GIS	1.00	infobox
Thrombomodulin	Band	20p11.21	1.00	infobox
Thrombomodulin	Band	2 G3\|2 73.45 cM	1.00	infobox
Thrombomodulin	Bgee	gingival epithelium	1.00	infobox
Thrombomodulin	Bgee	vena cava	1.00	infobox
Thrombomodulin	Bgee	right lung	1.00	infobox
Thrombomodulin	Bgee	skin of hip	1.00	infobox
Thrombomodulin	Bgee	skin of abdomen	1.00	infobox
Thrombomodulin	Bgee	skin of thigh	1.00	infobox
Thrombomodulin	Bgee	periodontal fiber	1.00	infobox
Thrombomodulin	Bgee	lower lobe of lung	1.00	infobox
Thrombomodulin	Bgee	upper lobe of left lung	1.00	infobox
Thrombomodulin	Bgee	left coronary artery	1.00	infobox
Thrombomodulin	Bgee	right lung lobe	1.00	infobox
Thrombomodulin	Bgee	left lung	1.00	infobox
Thrombomodulin	Bgee	left lung lobe	1.00	infobox
Thrombomodulin	Bgee	calvaria	1.00	infobox
Thrombomodulin	Bgee	Gonadal ridge	1.00	infobox
Thrombomodulin	Bgee	ankle	1.00	infobox
Thrombomodulin	Bgee	aortic valve	1.00	infobox
Thrombomodulin	Bgee	ascending aorta	1.00	infobox
Thrombomodulin	Bgee	white adipose tissue	1.00	infobox
Thrombomodulin	Bgee	decidua	1.00	infobox
Thrombomodulin	BioGPS	More reference expression data	1.00	infobox
Thrombomodulin	Chr.	Chromosome 20 (human)	1.00	infobox
Thrombomodulin	Chr.	Chromosome 2 (mouse)	1.00	infobox
Thrombomodulin	Databases	NCBI: entry; OMA: entry	1.00	infobox
Thrombomodulin	End	23,049,672 bp	1.00	infobox
Thrombomodulin	End	148,250,108 bp	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Thrombomodulin bring nearby vocabulary together. In this analysis, examples include Thrombin, Bdca-3 and Expressed. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Thrombomodulin
- Thrombin
- Bdca-3
- Expressed
- Function
- Surface
- Thbd
- Cells
- Gene
- Protein
- Human
- Cd141
- Cell
thrombomodulin
- Thrombin
- Bdca-3
- Expressed
- Function
- Surface
- Thbd
- Cells
- Gene
- Protein
- Human
- Cd141
- Cell
integral membrane protein
- Membrane
- Expressed
- Surface
- Activation
- Cofactor
- Protein
- Blood
- Cell
- Coagulation
- End
- Endothelial
- G3
blood coagulation
- Coagulation
- Anticoagulant
- Cell
- End
- G3
- Integral
- Membrane
- Mouse
- Procoagulant
- Search
- Activation
- Expressed
protein c
- Activation
- Cofactor
- Expressed
- Surface
- Thrombomodulin
- Thrombin
- Anticoagulant
- Blood
- Cell
- Coagulation
- End
- Endothelial
mesothelial cell
- Expressed
- Coagulation
- Dendritic
- End
- G3
- Human
- Integral
- Membrane
- Mouse
- Search
- Subset
- Activation
dendritic cell
- Subset
- Expressed
- Coagulation
- Dendritic
- End
- G3
- Human
- Integral
- Membrane
- Mouse
- Search
- Activation
function
- Search
- Location
- Thbd
- Chromosome
- Gene
- Bp
- Chr
- Thrombomodulin
- Human
- End
- G3
- Integral

Connections between topic areas Semantic bridges

For Thrombomodulin, one of the stronger structural bridges in this analysis connects Thrombomodulin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Thrombomodulin — Overview · splits 20 ⟂ 10

Thrombomodulin — Function · splits 21 ⟂ 9

Thrombomodulin — Genetics and structure · splits 22 ⟂ 8

Map overview Semantic statistics

Thrombomodulin

Nodes30

Edges29

Triples102

Avg. degree1.93

Density0.066667

Components1

Source & methodology

TTTA analyzes the structure around Thrombomodulin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Genetics and structure & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Thrombomodulin · EN edition · Analysis: TopicsToTalkAbout