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Platelet-activating factor

Platelet-activating factor, also known as PAF, PAF-acether or AGEPC (acetyl-glyceryl-ether-phosphorylcholine), is a potent phospholipid activator and mediator of many leukocyte functions, platelet aggregation and degranulation, inflammation, and anaphylaxis. It is also involved in changes to vascular permeability, the oxidative burst, chemotaxis of…

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Platelet-activating factor

Nodes73
Edges72
Triples46
Avg. degree1.97
Density0.027397
Components1

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Platelet-activating factor

Top relations

related to Inhibition · 26
Platelet-activating factor → Abellán Alemán, Allergol Immunopathol, ApafantLexipafant, Barrio, CS1, CV-3988, CYP2A6, Etizolam, Examples, Lock-gray-alt-2, Lock-green, Lock-red-alt-2, Madr, Miralles López JC, ModipafantA, Negro Alvarez JM, Ortiz Martínez JL, PAF, PAF Receptor, Platelet-activating
related to Structure · 8
Platelet-activating factor → C1, C2, Its, O-alkyl, PAF, Several, The, The C3
related to Regulation · 6
Platelet-activating factor → A2, Calcium, Cations, PAF, PAF-AH, The
see also · 1
Platelet-activating factor → Platelet-activating

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Important terminology

paf inflammatory platelet-activating factor pathway cells response produced also found activity inflammation phospholipid signaling function platelets antagonist role produce used

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
fragments of destroyed bacteria induce the synthesis of PAFinstance ofPAF causes life-threatening inflammation of the airways to induce asthma like symptoms.Toxins0.80text
which causes a drop in blood pressureinstance ofPAF causes life-threatening inflammation of the airways to induce asthma like symptoms.Toxins0.80text
reduced volume of blood pumped by the heartinstance ofPAF causes life-threatening inflammation of the airways to induce asthma like symptoms.Toxins0.80text
which leads to shockinstance ofPAF causes life-threatening inflammation of the airways to induce asthma like symptoms.Toxins0.80text
possibly deathinstance ofPAF causes life-threatening inflammation of the airways to induce asthma like symptoms.Toxins0.80text
Platelet-activating factorrelated to InhibitionPAF0.60section
Platelet-activating factorrelated to InhibitionExamples0.60section
Platelet-activating factorrelated to InhibitionCV-39880.60section
Platelet-activating factorrelated to InhibitionPAF Receptor0.60section
Platelet-activating factorrelated to InhibitionSM-125020.60section
Platelet-activating factorrelated to InhibitionCYP2A60.60section
Platelet-activating factorrelated to InhibitionRupatadine0.60section

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