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Apixaban

Apixaban, sold under the brand name Eliquis among others, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa. It is used as an alternative to warfarin to prevent blood clots following hip or knee replacement and in those with a…

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
B01AF02 (WHO)
Bioavailability
~50%
CAS Number
503612-47-3 Y
ChEMBL
ChEMBL231779 Y

Topics to explore

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Overview

Medical uses

Side effects

Mechanism of action

History

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Apixaban

Nodes64
Edges63
Triples92
Avg. degree1.97
Density0.03125
Components1

How this topic connects Entity context

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Apixaban

Top relations

related to Economics · 17
Apixaban → Apotex Inc, August, BMS, Canadian, Federal Circuit Court, In December, In July, In September, Micro Labs, Mylan, Pfizer, Sigmapharm, Sunshine Lake, The, Unichem, United States, US FDA
related to history · 16
Apixaban → ARISTOTLE, BMS, BMS-562247-01, Bristol-Myers Squibb, By, December, Drug Administration, During, European Union, FDA, In August, In March, May, NDA, Pfizer, US Food
related to Bleeding · 12
Apixaban → Andexanet, ARISTOTLE, Bleeding, Drug Administration, FDA, In, Large, NSAIDs, SNRIs, SSRIs, The, US Food
related to Medical uses · 7
Apixaban → DVT, For, PE, The, To, Treatment, VTE
Legal status · 6
Apixaban → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
related to Atrial fibrillation · 6
Apixaban → CHA2DS2-VASc, Clinical Excellence, Compared, DOACs, Health, National Institute
related to Mechanism of action · 2
Apixaban → Factor Xa, Xa
3D model (JSmol) · 1
Apixaban → Interactive image
AHFS/Drugs.com · 1
Apixaban → Monograph
ATC code · 1
Apixaban → B01AF02 (WHO)

Important terminology Word statistics

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Important terminology

bleeding people embolism risk may use stroke atrial fibrillation approved factor xa united states warfarin side us pfizer direct blood

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Apixaban3D model (JSmol)Interactive image1.00infobox
ApixabanAHFS/Drugs.comMonograph1.00infobox
ApixabanATC codeB01AF02 (WHO)1.00infobox
ApixabanBioavailability~50%1.00infobox
ApixabanCAS Number503612-47-3 Y1.00infobox
ApixabanChEMBLChEMBL231779 Y1.00infobox
ApixabanChemSpider8358471 Y1.00infobox
ApixabanCompTox Dashboard (EPA)DTXSID804365001.00infobox
ApixabanDrugBankDB07828 Y1.00infobox
ApixabanECHA InfoCard100.167.3321.00infobox
ApixabanElimination half-life9–14 h1.00infobox
ApixabanExcretionBile duct (75%), kidney (25%)1.00infobox
ApixabanFormulaC25H25N5O41.00infobox
ApixabanIUPHAR/BPS63901.00infobox
ApixabanKEGGD03213 Y1.00infobox
ApixabanLegal statusAU: S4 (Prescription only)1.00infobox
ApixabanLegal statusCA: ℞-only1.00infobox
ApixabanLegal statusUK: POM (Prescription only)1.00infobox
ApixabanLegal statusUS: ℞-only1.00infobox
ApixabanLegal statusEU: Rx-only1.00infobox
ApixabanLegal statusIn general: ℞ (Prescription only)1.00infobox
ApixabanLicense dataUS DailyMed: Apixaban1.00infobox
ApixabanMedlinePlusa6130321.00infobox
ApixabanMetabolismCYP3A4, CYP3A5, CYP1A2 and others1.00infobox
ApixabanMolar mass459.506 g·mol−11.00infobox
ApixabanOther namesBMS-562247-011.00infobox
ApixabanPregnancy categoryAU: C1.00infobox
ApixabanProtein binding~87%1.00infobox
ApixabanPubChem CID101829691.00infobox
ApixabanRoutes of administrationBy mouth1.00infobox

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