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Ticagrelor: Applications, Research & Art

Ticagrelor, sold under the brand name Brilinta among others, is a medication used for the prevention of stroke, heart attack and other events in people with acute coronary syndrome, meaning problems with blood supply in the coronary arteries. It acts as a platelet aggregation inhibitor by antagonising the P2Y12 receptor. The drug is produced by AstraZeneca.

Language: English [EN]
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Ticagrelor topic overview

The analysis highlights Applications, Research and Art as prominent areas in the source structure around Ticagrelor.

Related topics
51
Source areas
7
Connected nodes
58
Extracted relationships
92
Concept neighborhoods
15
Bridge connections
58

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 15 topics
Pharmacology · 10 topics
Interactions · 9 topics
Chemistry · 8 topics
Adverse effects · 5 topics
Medical uses · 2 topics
Research · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
B01AC24 (WHO)
Bioavailability
36%
CAS Number
274693-27-5 Y
ChEMBL
ChEMBL398435 N

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Interactions

Pharmacology

Chemistry

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Ticagrelor connects Entity context

The extracted context around Ticagrelor shows recurring relationship patterns in the source. For example, Ticagrelor → AR-C124910XX, Current, CYP2C9, CYP3A4, However, Inhibitors, John's, Levels, O-deethylation, P-glycoprotein, P-gp, St, The, There, This, While Another extracted example is Ticagrelor → ACS, Allergic, CAD, Caution, Discontinuation, Dyspnoea, Furthermore, People, The, Ventricular. Use these groups to spot repeated connection types before inspecting the individual relationships.

Ticagrelor

Top relations

related to Interactions · 16
Ticagrelor → AR-C124910XX, Current, CYP2C9, CYP3A4, However, Inhibitors, John's, Levels, O-deethylation, P-glycoprotein, P-gp, St, The, There, This, While
has effect · 10
Ticagrelor → ACS, Allergic, CAD, Caution, Discontinuation, Dyspnoea, Furthermore, People, The, Ventricular
related to Pharmacokinetics · 9
Ticagrelor → AR-C124910XX, Asian, Caucasians, CYP3A4, In Japanese, Plasma, The, These, They
related to Mechanism of action · 8
Ticagrelor → ADP, CYP2C19, Han Chinese CYP2C19, In, Like, Moreover, P2Y12, TIA
related to Research · 8
Ticagrelor → AstraZeneca, BMJ, FDA, In, It, NEJM, PLATO, The
Legal status · 4
Ticagrelor → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, US: ℞-only
related to Contraindications · 3
Ticagrelor → Contraindications, CYP3A4, P-450
related to Medical uses · 3
Ticagrelor → EU, In, US
related to Chemistry · 2
Ticagrelor → Biopharmaceutics Classification System, The
3D model (JSmol) · 1
Ticagrelor → Interactive image

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

people clopidogrel risk stroke acute coronary bleeding effects trial adverse events syndrome cyp3a4 increased evidence used use blood hepatic therapy

Ticagrelor relationships Subject–Predicate–Object triples

TTTA extracted 92 structured relationships around Ticagrelor. Examples in this analysis include Ticagrelor → 3D model (JSmol) → Interactive image and Ticagrelor → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Ticagrelor3D model (JSmol)Interactive image1.00infobox
TicagrelorAHFS/Drugs.comMonograph1.00infobox
TicagrelorATC codeB01AC24 (WHO)1.00infobox
TicagrelorBioavailability36%1.00infobox
TicagrelorCAS Number274693-27-5 Y1.00infobox
TicagrelorChEMBLChEMBL398435 N1.00infobox
TicagrelorChemSpider8047109 N1.00infobox
TicagrelorCompTox Dashboard (EPA)DTXSID9010093371.00infobox
TicagrelorDrugBankDB08816 Y1.00infobox
TicagrelorECHA InfoCard100.114.7461.00infobox
TicagrelorElimination half-life7 hrs (ticagrelor), 8.5 hrs (active metabolite AR-C124910XX)1.00infobox
TicagrelorExcretionBile duct1.00infobox
TicagrelorFormulaC23H28F2N6O4S1.00infobox
TicagrelorIUPHAR/BPS17651.00infobox
TicagrelorKEGGD09017 Y1.00infobox
TicagrelorLegal statusAU: S4 (Prescription only)1.00infobox
TicagrelorLegal statusCA: ℞-only1.00infobox
TicagrelorLegal statusUS: ℞-only1.00infobox
TicagrelorLegal statusEU: Rx-only1.00infobox
TicagrelorLicense dataUS DailyMed: Ticagrelor1.00infobox
TicagrelorMedlinePlusa6110501.00infobox
TicagrelorMetabolismLiver (CYP3A4)1.00infobox
TicagrelorMolar mass522.57 g·mol−11.00infobox
TicagrelorOther namesAZD-61401.00infobox
TicagrelorPregnancy categoryAU: B11.00infobox
TicagrelorProtein binding>99.7%1.00infobox
TicagrelorPubChem CID98714191.00infobox
TicagrelorRoutes of administrationBy mouth1.00infobox
TicagrelorTrade namesBrilinta, Brilique, others1.00infobox
TicagrelorUNIIGLH0314RVC1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Ticagrelor bring nearby vocabulary together. In this analysis, examples include People, Risk and Acute. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Ticagrelor
    • People
    • Risk
    • Acute
    • Coronary
    • Clopidogrel
    • Stroke
    • Syndrome
    • Trial
    • Bleeding
    • Asian
    • Plato
    • Therapy
  • ticagrelor
    • People
    • Risk
    • Acute
    • Coronary
    • Clopidogrel
    • Stroke
    • Syndrome
    • Trial
    • Bleeding
    • Asian
    • Plato
    • Therapy
  • stroke
    • Attack
    • Heart
    • Acute
    • Prasugrel
    • Coronary
    • People
    • Blood
    • Compared
    • Clopidogrel
    • Events
    • Syndrome
    • Ticagrelor
  • heart attack
    • Attack
    • Heart
    • Stroke
    • Blood
    • Events
    • Adverse
    • Drugs
    • Medication
    • Acute
    • Coronary
    • Prasugrel
    • Aspirin
  • acute coronary syndrome
    • Coronary
    • Syndrome
    • Stroke
    • People
    • Compared
    • Ticagrelor
    • Used
    • Trial
    • Prasugrel
    • Attack
    • Dyspnoea
    • Heart
  • clopidogrel
    • Compared
    • Mortality
    • Plato
    • Ticagrelor
    • Stroke
    • Risk
    • Trial
    • Prasugrel
    • People
    • Coronary
    • Drugs
    • Aspirin
  • japanese people
    • Acute
    • Coronary
    • Ticagrelor
    • Syndrome
    • Stroke
    • Clopidogrel
    • Caution
    • Compared
    • Hepatic
    • Impairment
    • Treatment
    • Adverse
  • adverse effects
    • Effects
    • May
    • Cyp3a4
    • Risk
    • Bleeding
    • Attack
    • Blood
    • Dyspnoea
    • Heart
    • Plasma
    • Use
    • Events

Connections between topic areas Semantic bridges

For Ticagrelor, one of the stronger structural bridges in this analysis connects Ticagrelor with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TicagrelorOverview · splits 43 ⟂ 16
TicagrelorPharmacology · splits 48 ⟂ 11
TicagrelorInteractions · splits 49 ⟂ 10
TicagrelorChemistry · splits 50 ⟂ 9
TicagrelorAdverse effects · splits 53 ⟂ 6
TicagrelorMedical uses · splits 56 ⟂ 3
TicagrelorResearch · splits 56 ⟂ 3

Map overview Semantic statistics

Ticagrelor

Nodes59
Edges58
Triples92
Avg. degree1.97
Density0.033898
Components1

Source & methodology

TTTA analyzes the structure around Ticagrelor to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Research & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Ticagrelor · EN edition · Analysis: TopicsToTalkAbout

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