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Clopidogrel

Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent (dual antiplatelet therapy). It is taken by mouth. Its effect starts about two…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
B01AC04 (WHO)
Bioavailability
>50%
CAS Number
113665-84-2 Y
ChEBI
CHEBI:37941 Y

Topics to explore

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Overview

Medical uses

Adverse effects

Interactions

Pharmacology

Society and culture

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Map overview Semantic statistics

Clopidogrel

Nodes73
Edges72
Triples110
Avg. degree1.97
Density0.027397
Components1

How this topic connects Entity context

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Clopidogrel

Top relations

related to Pharmacokinetics and metabolism · 20
Clopidogrel → After, C16, C3, C4, C7, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP3A, In, Only, P2Y12, P450, R-configuration, S-oxide, SH, The, These, This
related to Further reading · 13
Clopidogrel → Biotechnology Information, Bookshelf ID, Clopidogrel Therapy, CYP2C19 Genotype, Dean, In Pratt VM, McLeod HL, Medical Genetics Summaries, National Center, NBK84114, NCBI, PMID, Rubinstein WS
related to Interactions · 10
Clopidogrel → As, Clinical, Combination, CYP2C19, Drug Administration, FDA, In November, Naproxen, The, US Food
related to Pharmacogenetics · 7
Clopidogrel → CYP2C19, CYP2C19-poor, Drug Administration, FDA, P-450, People, The US Food
related to Economics · 5
Clopidogrel → Before, In, It, Plavix, US
Legal status · 4
Clopidogrel → AU: S4 (Prescription only), EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Mechanism of action · 4
Clopidogrel → ADP, P2Y12, Platelet, The
related to Medical uses · 4
Clopidogrel → American College, American Heart Association, Cardiology, Treatment
has effect · 3
Clopidogrel → Hemorrhage, Serious, Thrombotic
related to Pharmacology · 3
Clopidogrel → ADP, P2Y12, The

Important terminology Word statistics

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Important terminology

aspirin people cyp2c19 drug metabolite active antiplatelet us heart drugs bleeding proton-pump following coronary used adverse medical effects administration stroke

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Clopidogrel3D model (JSmol)Interactive image1.00infobox
ClopidogrelAHFS/Drugs.comMonograph1.00infobox
ClopidogrelATC codeB01AC04 (WHO)1.00infobox
ClopidogrelBioavailability>50%1.00infobox
ClopidogrelCAS Number113665-84-2 Y1.00infobox
ClopidogrelChEBICHEBI:37941 Y1.00infobox
ClopidogrelChEMBLChEMBL1771 Y1.00infobox
ClopidogrelChemSpider54632 Y1.00infobox
ClopidogrelCompTox Dashboard (EPA)DTXSID60228481.00infobox
ClopidogrelDrugBankDB00758 Y1.00infobox
ClopidogrelDuration of action5 days1.00infobox
ClopidogrelECHA InfoCard100.127.8411.00infobox
ClopidogrelElimination half-life7–8 hours (inactive metabolite)1.00infobox
ClopidogrelExcretion50% Kidney 46% bile duct1.00infobox
ClopidogrelFormulaC16H16ClNO2S1.00infobox
ClopidogrelIUPHAR/BPS71501.00infobox
ClopidogrelKEGGD07729 Y1.00infobox
ClopidogrelKEGGD00769 Y1.00infobox
ClopidogrelLegal statusAU: S4 (Prescription only)1.00infobox
ClopidogrelLegal statusUK: POM (Prescription only)1.00infobox
ClopidogrelLegal statusUS: ℞-only1.00infobox
ClopidogrelLegal statusEU: Rx-only1.00infobox
ClopidogrelLicense dataUS DailyMed: Clopidogrel1.00infobox
ClopidogrelMedlinePlusa6010401.00infobox
ClopidogrelMetabolismLiver1.00infobox
ClopidogrelMolar mass321.82 g·mol−11.00infobox
ClopidogrelOnset of action2 hours1.00infobox
ClopidogrelPDB ligandCGE (PDBe, RCSB PDB)1.00infobox
ClopidogrelPregnancy categoryAU: B11.00infobox
ClopidogrelPronunciation/kləˈpɪdəɡrɛl, kloʊ-/1.00infobox

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