GATA1

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GATA1 topic overview

The analysis highlights GATA1 proteins, Genetic disorders and Gene as prominent areas in the source structure around GATA1.

Related topics: 158
Source areas: 6
Connected nodes: 164
Extracted relationships: 227
Concept neighborhoods: 40
Bridge connections: 164

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 65 topics

Genetic disorders · 39 topics

GATA1 proteins · 25 topics

Gene · 14 topics

Physiology and Pathology · 11 topics

GATA1 in myelofibrosis · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT, GATA binding protein 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GNF, 1Y0J, 2L5E, 2L6Y, 2L6Z, 3VD6, 3VEK
Band: Xp11.23 · X A1.1|X 3.59 cM
Bgee: trabecular bone · blood · bone marrow · monocyte · bone marrow cell
BioGPS: More reference expression data
Chr.: X chromosome (human) · X chromosome (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

GATA1 in myelofibrosis

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GATA1 connects Entity context

The extracted context around GATA1 shows recurring relationship patterns in the source. For example, GATA1 → anatomical structure formation involved in morphogenesis, animal organ morphogenesis, basophil differentiation, blood coagulation, C2H2 zinc finger domain binding, cell development, cell-cell signaling, cellular response to thyroid hormone stimulus, chromatin binding, chromatin DNA binding, cis-regulatory region sequence-specific DNA binding, dendritic cell differentiation, development of the heart, digestive tract development, DNA binding, DNA binding, bending, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific Another extracted example is GATA1 → A/G, AML, Apparently, Based, BRD3, BRD4, BRG1, C-terminus, C-ZnF, CTBP1, Displacement, DNA, DNA-associated, DNA-specific, FLI1, FOG1, FOG2, GATA, GATA1-FOG1, GATA1-inhibiting. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 66

GATA1 → anatomical structure formation involved in morphogenesis, animal organ morphogenesis, basophil differentiation, blood coagulation, C2H2 zinc finger domain binding, cell development, cell-cell signaling, cellular response to thyroid hormone stimulus, chromatin binding, chromatin DNA binding, cis-regulatory region sequence-specific DNA binding, dendritic cell differentiation, development of the heart, digestive tract development, DNA binding, DNA binding, bending, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific

related to GATA1 proteins · 38

GATA1 → A/G, AML, Apparently, Based, BRD3, BRD4, BRG1, C-terminus, C-ZnF, CTBP1, Displacement, DNA, DNA-associated, DNA-specific, FLI1, FOG1, FOG2, GATA, GATA1-FOG1, GATA1-inhibiting

Bgee · 17

GATA1 → blood, body of femur, bone marrow, bone marrow cell, embryo, fetal liver hematopoietic progenitor cell, gallbladder, granulocyte, human fetus, monocyte, morula, right lung, spleen, tibiofemoral joint, trabecular bone, upper lobe of left lung, yolk sac

RNA expression pattern · 17

related to Diamond–Blackfan anemia · 17

GATA1 → About, Blackfan, Diamond, Diamond Blackfan, GATA1-S, However, In, It, Other, RPL11, RPL35A, RPL5, RPS19, RPS24, RPS26, The, These GATA1

related to Combined anemia-thrombocytopenia syndromes · 16

GATA1 → Certain GATA1-inactivating, D218G, D218Y, DNA, G208R, G208S, G209S, R216Q, R216W, Single-nucleotide, Structural, The, These, These GATA1, V205M, X-linked

related to Gene · 11

GATA1 → C-ZnF, Gata-1, Gata1-deficient, Gata1-knockout, GATA1-S, It, Lacking, N-ZnF, Studies, The, These

related to Physiology and Pathology · 7

GATA1 → Also, Based, GATA1-inactivating, Reduced, Subsequent, These, This

related to Genetic disorders · 6

GATA1 → Down, GATA1-S, In, Mutations, N-ZnF, X-linked

related to GATA1 in myelofibrosis · 4

GATA1 → Myelofibrosis, Recent, The, Ultimately

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mutations cells blood red platelets disease genes cell gene platelet anemia disorder maturation syndrome human reduced levels chromosome development transcription

GATA1 relationships Subject–Predicate–Object triples

TTTA extracted 227 structured relationships around GATA1. Examples in this analysis include GATA1 → Aliases → GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT, GATA binding protein 1 and GATA1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GNF, 1Y0J, 2L5E, 2L6Y, 2L6Z, 3VD6, 3VEK. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
GATA1	Aliases	GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT, GATA binding protein 1	1.00	infobox
GATA1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GNF, 1Y0J, 2L5E, 2L6Y, 2L6Z, 3VD6, 3VEK	1.00	infobox
GATA1	Band	Xp11.23	1.00	infobox
GATA1	Band	X A1.1\|X 3.59 cM	1.00	infobox
GATA1	Bgee	trabecular bone	1.00	infobox
GATA1	Bgee	blood	1.00	infobox
GATA1	Bgee	bone marrow	1.00	infobox
GATA1	Bgee	monocyte	1.00	infobox
GATA1	Bgee	bone marrow cell	1.00	infobox
GATA1	Bgee	granulocyte	1.00	infobox
GATA1	Bgee	right lung	1.00	infobox
GATA1	Bgee	upper lobe of left lung	1.00	infobox
GATA1	Bgee	spleen	1.00	infobox
GATA1	Bgee	gallbladder	1.00	infobox
GATA1	Bgee	fetal liver hematopoietic progenitor cell	1.00	infobox
GATA1	Bgee	tibiofemoral joint	1.00	infobox
GATA1	Bgee	embryo	1.00	infobox
GATA1	Bgee	morula	1.00	infobox
GATA1	Bgee	yolk sac	1.00	infobox
GATA1	Bgee	body of femur	1.00	infobox
GATA1	Bgee	human fetus	1.00	infobox
GATA1	BioGPS	More reference expression data	1.00	infobox
GATA1	Chr.	X chromosome (human)	1.00	infobox
GATA1	Chr.	X chromosome (mouse)	1.00	infobox
GATA1	Databases	NCBI: entry; OMA: entry	1.00	infobox
GATA1	End	48,794,311 bp	1.00	infobox
GATA1	End	7,844,310 bp	1.00	infobox
GATA1	Ensembl	ENSG00000102145	1.00	infobox
GATA1	Entrez	2623	1.00	infobox
GATA1	External IDs	OMIM: 305371; MGI: 95661; GeneCards: GATA1	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GATA1 bring nearby vocabulary together. In this analysis, examples include Mutations, Gene and Cells. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

GATA1
- Mutations
- Gene
- Cells
- Blood
- Gata1-s
- Inactivating
- Development
- Reduced
- Red
- Myelofibrosis
- Genes
- Cause
gata1
- Mutations
- Gene
- Cells
- Blood
- Gata1-s
- Inactivating
- Development
- Reduced
- Red
- Myelofibrosis
- Genes
- Cause
gata family of transcription factors
- Factor
- Gene
- Cell
- Gata1
- Blood
- Bone
- Studies
- Marrow
- Myelofibrosis
- Protein
- Cause
- Development
x chromosome
- Human
- Gene
- Disorder
- Syndrome
- Mutations
- Transient
- Leukemia
- Marrow
- Protein
- Result
- Gata1
- Development
inactivating mutations
- Mutations
- Result
- Reduced
- Associated
- Syndrome
- Protein
- Disease
- Anemia
- Individuals
- Disorder
- Platelet
- Gata1-s
diamond–blackfan anemia
- Mild
- Disease
- Associated
- Platelet
- Red
- Disorder
- Syndrome
- Bone
- Transient
- Leukemia
- Marrow
- Blood
anemia
- Mild
- Disease
- Associated
- Platelet
- Red
- Disorder
- Syndrome
- Bone
- Transient
- Leukemia
- Marrow
- Blood
bone marrow
- Marrow
- Myelofibrosis
- Cell
- Cells
- Platelet
- Levels
- Human
- Reduced
- Megakaryoblasts
- Factor
- Mild
- Formation

Connections between topic areas Semantic bridges

For GATA1, one of the stronger structural bridges in this analysis connects GATA1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

GATA1 — Overview · splits 99 ⟂ 66

GATA1 — Genetic disorders · splits 125 ⟂ 40

GATA1 — GATA1 proteins · splits 139 ⟂ 26

GATA1 — Gene · splits 150 ⟂ 15

GATA1 — Physiology and Pathology · splits 153 ⟂ 12

GATA1 — GATA1 in myelofibrosis · splits 160 ⟂ 5

Map overview Semantic statistics

GATA1

Nodes165

Edges164

Triples227

Avg. degree1.99

Density0.012121

Components1

Source & methodology

TTTA analyzes the structure around GATA1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as GATA1 proteins, Genetic disorders & Gene, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GATA1 · EN edition · Analysis: TopicsToTalkAbout