Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

GATA1

GATA-binding factor 1 or GATA-1 (also termed Erythroid transcription factor) is the founding member of the GATA family of transcription factors. This protein is widely expressed throughout vertebrate species. In humans and mice, it is encoded by the GATA1 and Gata1 genes, respectively. These genes are located on the X chromosome in both species.

GATA1 proteins, Genetic disorders & Gene

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around GATA1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT, GATA binding protein 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GNF, 1Y0J, 2L5E, 2L6Y, 2L6Z, 3VD6, 3VEK
Band
Xp11.23 · X A1.1|X 3.59 cM
Bgee
trabecular bone · blood · bone marrow · monocyte · bone marrow cell
BioGPS
More reference expression data
Chr.
X chromosome (human) · X chromosome (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Gene

GATA1 proteins

Physiology and Pathology

Genetic disorders

GATA1 in myelofibrosis

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

GATA1

Nodes165
Edges164
Triples227
Avg. degree1.99
Density0.012121
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

GATA1

Top relations

Gene ontology · 66
GATA1 → anatomical structure formation involved in morphogenesis, animal organ morphogenesis, basophil differentiation, blood coagulation, C2H2 zinc finger domain binding, cell development, cell-cell signaling, cellular response to thyroid hormone stimulus, chromatin binding, chromatin DNA binding, cis-regulatory region sequence-specific DNA binding, dendritic cell differentiation, development of the heart, digestive tract development, DNA binding, DNA binding, bending, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific
related to GATA1 proteins · 38
GATA1 → A/G, AML, Apparently, Based, BRD3, BRD4, BRG1, C-terminus, C-ZnF, CTBP1, Displacement, DNA, DNA-associated, DNA-specific, FLI1, FOG1, FOG2, GATA, GATA1-FOG1, GATA1-inhibiting
Bgee · 17
GATA1 → blood, body of femur, bone marrow, bone marrow cell, embryo, fetal liver hematopoietic progenitor cell, gallbladder, granulocyte, human fetus, monocyte, morula, right lung, spleen, tibiofemoral joint, trabecular bone, upper lobe of left lung, yolk sac
RNA expression pattern · 17
GATA1 → blood, body of femur, bone marrow, bone marrow cell, embryo, fetal liver hematopoietic progenitor cell, gallbladder, granulocyte, human fetus, monocyte, morula, right lung, spleen, tibiofemoral joint, trabecular bone, upper lobe of left lung, yolk sac
related to Diamond–Blackfan anemia · 17
GATA1 → About, Blackfan, Diamond, Diamond Blackfan, GATA1-S, However, In, It, Other, RPL11, RPL35A, RPL5, RPS19, RPS24, RPS26, The, These GATA1
related to Combined anemia-thrombocytopenia syndromes · 16
GATA1 → Certain GATA1-inactivating, D218G, D218Y, DNA, G208R, G208S, G209S, R216Q, R216W, Single-nucleotide, Structural, The, These, These GATA1, V205M, X-linked
related to Gene · 11
GATA1 → C-ZnF, Gata-1, Gata1-deficient, Gata1-knockout, GATA1-S, It, Lacking, N-ZnF, Studies, The, These
related to Physiology and Pathology · 7
GATA1 → Also, Based, GATA1-inactivating, Reduced, Subsequent, These, This
related to Genetic disorders · 6
GATA1 → Down, GATA1-S, In, Mutations, N-ZnF, X-linked
related to GATA1 in myelofibrosis · 4
GATA1 → Myelofibrosis, Recent, The, Ultimately

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mutations cells blood red platelets disease genes cell gene platelet anemia disorder maturation syndrome human reduced levels chromosome development transcription

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
GATA1AliasesGATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT, GATA binding protein 11.00infobox
GATA1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GNF, 1Y0J, 2L5E, 2L6Y, 2L6Z, 3VD6, 3VEK1.00infobox
GATA1BandXp11.231.00infobox
GATA1BandX A1.1|X 3.59 cM1.00infobox
GATA1Bgeetrabecular bone1.00infobox
GATA1Bgeeblood1.00infobox
GATA1Bgeebone marrow1.00infobox
GATA1Bgeemonocyte1.00infobox
GATA1Bgeebone marrow cell1.00infobox
GATA1Bgeegranulocyte1.00infobox
GATA1Bgeeright lung1.00infobox
GATA1Bgeeupper lobe of left lung1.00infobox
GATA1Bgeespleen1.00infobox
GATA1Bgeegallbladder1.00infobox
GATA1Bgeefetal liver hematopoietic progenitor cell1.00infobox
GATA1Bgeetibiofemoral joint1.00infobox
GATA1Bgeeembryo1.00infobox
GATA1Bgeemorula1.00infobox
GATA1Bgeeyolk sac1.00infobox
GATA1Bgeebody of femur1.00infobox
GATA1Bgeehuman fetus1.00infobox
GATA1BioGPSMore reference expression data1.00infobox
GATA1Chr.X chromosome (human)1.00infobox
GATA1Chr.X chromosome (mouse)1.00infobox
GATA1DatabasesNCBI: entry; OMA: entry1.00infobox
GATA1End48,794,311 bp1.00infobox
GATA1End7,844,310 bp1.00infobox
GATA1EnsemblENSG000001021451.00infobox
GATA1Entrez26231.00infobox
GATA1External IDsOMIM: 305371; MGI: 95661; GeneCards: GATA11.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.