Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

KMT5A: Overview, Related Topics & Entities

N-lysine methyltransferase KMT5A is an enzyme that in humans is encoded by the KMT5A gene. The enzyme is a histone methyltransferase, SET domain-containing and lysine-specific. The enzyme transfers one methyl group to histone H4 lysine residue at position 20. S-Adenosyl methionine (SAM) is both the cofactor and the methyl group donor. The lysine residue…

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

KMT5A topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around KMT5A.

Related topics
9
Source areas
1
Connected nodes
10
Extracted relationships
91
Related term clusters
11
Bridge connections
10

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 9 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.1.1.354
↗
2.1.1.361
↗
Aliases
KMT5A, PR-Set7, SET07, SET8, SETD8, lysine methyltransferase 5A, PR/SET07
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZKK, 2BQZ, 3F9W, 3F9X, 3F9Y, 3F9Z, 4IJ8, 5HQ2
Band
12q24.31 · 5|5 F
Bgee
sural nerve · ventricular zone · right coronary artery · thoracic aorta · ascending aorta

Start with your topic. Discover where to go next.

Explore different angles and find fresh ideas to shape your next piece of content.

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How KMT5A connects Entity context

The extracted context around KMT5A shows recurring relationship patterns in the source. For example, KMT5A → cell cycle, cell division, chromatin organization, chromosome, cytosol, histone H4-K20 methylation, histone lysine methylation, histone methyltransferase activity (H4-K20 specific), histone-lysine N-methyltransferase activity, lysine N-methyltransferase activity, methylation, methyltransferase activity, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nucleoplasm, nucleus, p53 binding, peptidyl-lysine monomethylation, protein binding, protein-lysine N-methyltransferase activity Another extracted example is KMT5A → Achilles tendon, ascending aorta, body of pancreas, Descending thoracic aorta, gastrula, genital tubercle, granulocyte, knee joint, lip, muscle of thigh, popliteal artery, pyloric antrum, right coronary artery, right lobe of thyroid gland, sural nerve, tail of embryo, thoracic aorta, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

KMT5A

Top relations

Gene ontology · 26
KMT5A → cell cycle, cell division, chromatin organization, chromosome, cytosol, histone H4-K20 methylation, histone lysine methylation, histone methyltransferase activity (H4-K20 specific), histone-lysine N-methyltransferase activity, lysine N-methyltransferase activity, methylation, methyltransferase activity, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nucleoplasm, nucleus, p53 binding, peptidyl-lysine monomethylation, protein binding, protein-lysine N-methyltransferase activity
Bgee · 19
KMT5A → Achilles tendon, ascending aorta, body of pancreas, Descending thoracic aorta, gastrula, genital tubercle, granulocyte, knee joint, lip, muscle of thigh, popliteal artery, pyloric antrum, right coronary artery, right lobe of thyroid gland, sural nerve, tail of embryo, thoracic aorta, ventricular zone, zygote
RNA expression pattern · 19
KMT5A → Achilles tendon, ascending aorta, body of pancreas, Descending thoracic aorta, gastrula, genital tubercle, granulocyte, knee joint, lip, muscle of thigh, popliteal artery, pyloric antrum, right coronary artery, right lobe of thyroid gland, sural nerve, tail of embryo, thoracic aorta, ventricular zone, zygote
Band · 2
KMT5A → 12q24.31, 5|5 F
Chr. · 2
KMT5A → Chromosome 12 (human), Chromosome 5 (mouse)
End · 2
KMT5A → 123,409,353 bp, 124,600,371 bp
2.1.1.354 · 1
KMT5A → ↗
2.1.1.361 · 1
KMT5A → ↗
Aliases · 1
KMT5A → KMT5A, PR-Set7, SET07, SET8, SETD8, lysine methyltransferase 5A, PR/SET07
Available structures · 1
KMT5A → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZKK, 2BQZ, 3F9W, 3F9X, 3F9Y, 3F9Z, 4IJ8, 5HQ2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

lysine bp enzyme chr histone human chromosome band methyltransferase gene 12 methyl group residue location h4 position 20 mouse search

KMT5A relationships Subject–Predicate–Object triples

TTTA extracted 91 structured relationships around KMT5A. Examples in this analysis include KMT5A → 2.1.1.354 → ↗ and KMT5A → Aliases → KMT5A, PR-Set7, SET07, SET8, SETD8, lysine methyltransferase 5A, PR/SET07. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
KMT5A2.1.1.354↗1.00infobox
KMT5A2.1.1.361↗1.00infobox
KMT5AAliasesKMT5A, PR-Set7, SET07, SET8, SETD8, lysine methyltransferase 5A, PR/SET071.00infobox
KMT5AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZKK, 2BQZ, 3F9W, 3F9X, 3F9Y, 3F9Z, 4IJ8, 5HQ21.00infobox
KMT5ABand12q24.311.00infobox
KMT5ABand5|5 F1.00infobox
KMT5ABgeesural nerve1.00infobox
KMT5ABgeeventricular zone1.00infobox
KMT5ABgeeright coronary artery1.00infobox
KMT5ABgeethoracic aorta1.00infobox
KMT5ABgeeascending aorta1.00infobox
KMT5ABgeeDescending thoracic aorta1.00infobox
KMT5ABgeeAchilles tendon1.00infobox
KMT5ABgeeright lobe of thyroid gland1.00infobox
KMT5ABgeebody of pancreas1.00infobox
KMT5ABgeepopliteal artery1.00infobox
KMT5ABgeetail of embryo1.00infobox
KMT5ABgeegenital tubercle1.00infobox
KMT5ABgeegastrula1.00infobox
KMT5ABgeegranulocyte1.00infobox
KMT5ABgeemuscle of thigh1.00infobox
KMT5ABgeepyloric antrum1.00infobox
KMT5ABgeezygote1.00infobox
KMT5ABgeelip1.00infobox
KMT5ABgeeknee joint1.00infobox
KMT5ABioGPSMore reference expression data1.00infobox
KMT5AChr.Chromosome 12 (human)1.00infobox
KMT5AChr.Chromosome 5 (mouse)1.00infobox
KMT5ADatabasesNCBI: entry; OMA: entry1.00infobox
KMT5AEnd123,409,353 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around KMT5A bring nearby vocabulary together. In this analysis, examples include Gene, Methyltransferase and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • enzyme
    • Histone
    • Methyltransferase
    • H4
    • Position
    • Group
    • Kmt5a
    • Methyl
    • Residue
    • Gene
    • Lysine
    • Domain-containing
    • Encoded
  • KMT5A
    • Gene
    • Methyltransferase
    • Activity
    • Search
    • Location
    • Chromosome
    • Enzyme
    • Histone
    • Human
    • Lysine
    • Bp
    • Chr
  • kmt5a
    • Gene
    • Methyltransferase
    • Activity
    • Search
    • Location
    • Chromosome
    • Enzyme
    • Histone
    • Human
    • Lysine
    • Bp
    • Chr
  • histone h4
    • Position
    • Methyl
    • Residue
    • Lysine
    • Methyltransferase
    • Activity
    • H4
    • Histone
    • One
    • Search
    • Transfers
    • Group
  • gene
    • Kmt5a
    • Location
    • Chromosome
    • Human
    • Methyltransferase
    • Activity
    • Bp
    • Chr
    • End
    • Mouse
    • Search
    • Band
  • methyl group
    • Group
    • Methyl
    • H4
    • Position
    • Residue
    • Histone
    • Lysine
    • Cofactor
    • Methionine
    • One
    • S-adenosyl
    • Transfers
  • lysine
    • Residue
    • Activity
    • Position
    • Search
    • Location
    • Methyl
    • Chromosome
    • Human
    • Methyltransferase
    • Bp
    • Chr
    • N6-methyllysine
  • set domain-containing and lysine-specific
    • Domain-containing
    • Lysine-specific
    • Set
    • Enzyme
    • Histone
    • Methyltransferase

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the KMT5A map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

KMT5A

Nodes11
Edges10
Triples91
Avg. degree1.82
Density0.181818
Components1

Source & methodology

TTTA analyzes the structure around KMT5A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — KMT5A · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.

Monitor your Domain Rating with FrogDR