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SUZ12: Regions, Function & Overview

Polycomb protein SUZ12 is a protein that in humans is encoded by the SUZ12 gene.

Language: English [EN]
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SUZ12 topic overview

The analysis highlights Regions, Function and Overview as prominent areas in the source structure around SUZ12.

Related topics
9
Source areas
2
Connected nodes
11
Extracted relationships
102
Concept neighborhoods
5
Bridge connections
11

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 7 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SUZ12, CHET9, JJAZ1, SUZ12 polycomb repressive complex 2 subunit, polycomb repressive complex 2 subunit, IMMAS
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5IJ7, 5IJ8, 5HYN
Band
17q11.2 · 11 B5|11 47.36 cM
Bgee
trabecular bone · mucosa of paranasal sinus · buccal mucosa cell · Epithelium of choroid plexus · pylorus
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SUZ12 connects Entity context

The extracted context around SUZ12 shows recurring relationship patterns in the source. For example, SUZ12 → chromatin binding, chromatin DNA binding, chromatin organization, ESC/E(Z) complex, histone H3-K27 methylation, histone methylation, histone methyltransferase activity, histone methyltransferase activity (H3-K27 specific), histone ubiquitination, metal ion binding, methylated histone binding, negative regulation of cell differentiation, negative regulation of G0 to G1 transition, negative regulation of gene expression, epigenetic, negative regulation of transcription by RNA polymerase II, nuclear body, nucleolus, nucleoplasm, nucleus, positive regulation of cell population proliferation Another extracted example is SUZ12 → atrioventricular valve, buccal mucosa cell, cartilage tissue, Epithelium of choroid plexus, hair follicle, medullary collecting duct, mucosa of paranasal sinus, otic placode, primary oocyte, pylorus, renal corpuscle, renal medulla, saccule, secondary oocyte, seminal vesicula, tail of embryo, trabecular bone, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

SUZ12

Top relations

Gene ontology · 31
SUZ12 → chromatin binding, chromatin DNA binding, chromatin organization, ESC/E(Z) complex, histone H3-K27 methylation, histone methylation, histone methyltransferase activity, histone methyltransferase activity (H3-K27 specific), histone ubiquitination, metal ion binding, methylated histone binding, negative regulation of cell differentiation, negative regulation of G0 to G1 transition, negative regulation of gene expression, epigenetic, negative regulation of transcription by RNA polymerase II, nuclear body, nucleolus, nucleoplasm, nucleus, positive regulation of cell population proliferation
Bgee · 19
SUZ12 → atrioventricular valve, buccal mucosa cell, cartilage tissue, Epithelium of choroid plexus, hair follicle, medullary collecting duct, mucosa of paranasal sinus, otic placode, primary oocyte, pylorus, renal corpuscle, renal medulla, saccule, secondary oocyte, seminal vesicula, tail of embryo, trabecular bone, ventricular zone, zygote
RNA expression pattern · 19
SUZ12 → atrioventricular valve, buccal mucosa cell, cartilage tissue, Epithelium of choroid plexus, hair follicle, medullary collecting duct, mucosa of paranasal sinus, otic placode, primary oocyte, pylorus, renal corpuscle, renal medulla, saccule, secondary oocyte, seminal vesicula, tail of embryo, trabecular bone, ventricular zone, zygote
related to Function · 8
SUZ12 → HOTAIR, JAZF1, Polycomb Repressive Complex, PRC2, Recombination, RNA, The, This
Band · 2
SUZ12 → 11 B5|11 47.36 cM, 17q11.2
Chr. · 2
SUZ12 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
SUZ12 → 32,001,038 bp, 79,924,949 bp
Aliases · 1
SUZ12 → SUZ12, CHET9, JJAZ1, SUZ12 polycomb repressive complex 2 subunit, polycomb repressive complex 2 subunit, IMMAS
Available structures · 1
SUZ12 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5IJ7, 5IJ8, 5HYN
BioGPS · 1
SUZ12 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp chr human band chromosome 17 protein polycomb location function complex mouse external encoded search 001 038 end 32

SUZ12 relationships Subject–Predicate–Object triples

TTTA extracted 102 structured relationships around SUZ12. Examples in this analysis include SUZ12 → Aliases → SUZ12, CHET9, JJAZ1, SUZ12 polycomb repressive complex 2 subunit, polycomb repressive complex 2 subunit, IMMAS and SUZ12 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5IJ7, 5IJ8, 5HYN. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SUZ12AliasesSUZ12, CHET9, JJAZ1, SUZ12 polycomb repressive complex 2 subunit, polycomb repressive complex 2 subunit, IMMAS1.00infobox
SUZ12Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5IJ7, 5IJ8, 5HYN1.00infobox
SUZ12Band17q11.21.00infobox
SUZ12Band11 B5|11 47.36 cM1.00infobox
SUZ12Bgeetrabecular bone1.00infobox
SUZ12Bgeemucosa of paranasal sinus1.00infobox
SUZ12Bgeebuccal mucosa cell1.00infobox
SUZ12BgeeEpithelium of choroid plexus1.00infobox
SUZ12Bgeepylorus1.00infobox
SUZ12Bgeerenal medulla1.00infobox
SUZ12Bgeeseminal vesicula1.00infobox
SUZ12Bgeehair follicle1.00infobox
SUZ12Bgeecartilage tissue1.00infobox
SUZ12Bgeeventricular zone1.00infobox
SUZ12Bgeemedullary collecting duct1.00infobox
SUZ12Bgeezygote1.00infobox
SUZ12Bgeesecondary oocyte1.00infobox
SUZ12Bgeerenal corpuscle1.00infobox
SUZ12Bgeeprimary oocyte1.00infobox
SUZ12Bgeeatrioventricular valve1.00infobox
SUZ12Bgeesaccule1.00infobox
SUZ12Bgeetail of embryo1.00infobox
SUZ12Bgeeotic placode1.00infobox
SUZ12BioGPSMore reference expression data1.00infobox
SUZ12Chr.Chromosome 17 (human)1.00infobox
SUZ12Chr.Chromosome 11 (mouse)1.00infobox
SUZ12DatabasesNCBI: entry; OMA: entry1.00infobox
SUZ12End32,001,038 bp1.00infobox
SUZ12End79,924,949 bp1.00infobox
SUZ12EnsemblENSG000001786911.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SUZ12 bring nearby vocabulary together. In this analysis, examples include Domain, Zinc and Finger. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Function
    • Location
    • Protein
    • Chromosome
    • Human
    • Suz12
    • Bp
    • Chr
    • B5
    • Breakpoints
    • End
    • Finger
  • function
    • Search
    • Specific
    • Complex
    • Location
    • Gene
    • Chromosome
    • Human
    • Suz12
    • Bp
    • Chr
    • External
    • Links
  • protein
    • Finger
    • Region
    • Zinc
    • Suz12
    • B5
    • Breakpoints
    • Chromatin
    • Domain
    • End
    • Mouse
    • Rna
    • Search
  • SUZ12
    • Domain
    • Zinc
  • suz12
    • Domain
    • Zinc

Connections between topic areas Semantic bridges

For SUZ12, one of the stronger structural bridges in this analysis connects SUZ12 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SUZ12Function · splits 4 ⟂ 8
SUZ12Overview · splits 9 ⟂ 3

Map overview Semantic statistics

SUZ12

Nodes12
Edges11
Triples102
Avg. degree1.83
Density0.166667
Components1

Source & methodology

TTTA analyzes the structure around SUZ12 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SUZ12 · EN edition · Analysis: TopicsToTalkAbout

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