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Thrombopoietin receptor: Discovery, Clinical relevance & Interactions

The thrombopoietin receptor also known as the myeloproliferative leukemia protein or CD110 (Cluster of Differentiation 110) is a protein that in humans is encoded by the MPL (myeloproliferative leukemia virus) oncogene.

Language: English [EN]
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Thrombopoietin receptor topic overview

The analysis highlights Discovery, Clinical relevance and Interactions as prominent areas in the source structure around Thrombopoietin receptor.

Related topics
14
Source areas
5
Connected nodes
19
Extracted relationships
86
Concept neighborhoods
8
Bridge connections
19

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical relevance · 4 topics
Discovery · 4 topics
Interactions · 3 topics
Overview · 2 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MPL, C-CD110, MPLV, THCYT2, TPOR, MPL proto-oncogene, thrombopoietin receptor, THPOR
Band
1p34.2 · 4 D2.1|4 54.61 cM
Bgee
testicle · mononuclear cell · monocyte · right frontal lobe · bone marrow cell
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Discovery

Function

Interactions

Clinical relevance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Thrombopoietin receptor connects Entity context

The extracted context around Thrombopoietin receptor shows recurring relationship patterns in the source. For example, Thrombopoietin receptor → basophil homeostasis, cell population proliferation, cell surface, cell surface receptor signaling pathway, cellular response to hypoxia, cytokine receptor activity, cytokine-mediated signaling pathway, eosinophil homeostasis, Golgi apparatus, integral component of membrane, integral component of plasma membrane, membrane, monocyte homeostasis, neuron projection, neutrophil homeostasis, plasma membrane, platelet aggregation, positive regulation of lymphocyte proliferation, positive regulation of platelet formation, protein binding Another extracted example is Thrombopoietin receptor → blood, bone marrow cell, Brodmann area 9, bronchial epithelial cell, dorsal aorta, embryo, gastrula, left ovary, monocyte, mononuclear cell, morula, prefrontal cortex, right frontal lobe, spleen, sural nerve, testicle, tibiofemoral joint, vasculature of trunk, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

Thrombopoietin receptor

Top relations

Gene ontology · 24
Thrombopoietin receptor → basophil homeostasis, cell population proliferation, cell surface, cell surface receptor signaling pathway, cellular response to hypoxia, cytokine receptor activity, cytokine-mediated signaling pathway, eosinophil homeostasis, Golgi apparatus, integral component of membrane, integral component of plasma membrane, membrane, monocyte homeostasis, neuron projection, neutrophil homeostasis, plasma membrane, platelet aggregation, positive regulation of lymphocyte proliferation, positive regulation of platelet formation, protein binding
Bgee · 19
Thrombopoietin receptor → blood, bone marrow cell, Brodmann area 9, bronchial epithelial cell, dorsal aorta, embryo, gastrula, left ovary, monocyte, mononuclear cell, morula, prefrontal cortex, right frontal lobe, spleen, sural nerve, testicle, tibiofemoral joint, vasculature of trunk, yolk sac
RNA expression pattern · 19
Thrombopoietin receptor → blood, bone marrow cell, Brodmann area 9, bronchial epithelial cell, dorsal aorta, embryo, gastrula, left ovary, monocyte, mononuclear cell, morula, prefrontal cortex, right frontal lobe, spleen, sural nerve, testicle, tibiofemoral joint, vasculature of trunk, yolk sac
related to Clinical relevance · 4
Thrombopoietin receptor → In, Inactivating, Specific, These
Band · 2
Thrombopoietin receptor → 1p34.2, 4 D2.1|4 54.61 cM
Chr. · 2
Thrombopoietin receptor → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
Thrombopoietin receptor → 118,314,710 bp, 43,354,466 bp
Aliases · 1
Thrombopoietin receptor → MPL, C-CD110, MPLV, THCYT2, TPOR, MPL proto-oncogene, thrombopoietin receptor, THPOR
BioGPS · 1
Thrombopoietin receptor → More reference expression data
Databases · 1
Thrombopoietin receptor → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

thrombopoietin human bp protein gene chr band receptor mpl chromosome c-mpl cd110 leukemia formation location oncogene mutations myeloproliferative encoded virus

Thrombopoietin receptor relationships Subject–Predicate–Object triples

TTTA extracted 86 structured relationships around Thrombopoietin receptor. Examples in this analysis include Thrombopoietin receptor → Aliases → MPL, C-CD110, MPLV, THCYT2, TPOR, MPL proto-oncogene, thrombopoietin receptor, THPOR and Thrombopoietin receptor → Band → 1p34.2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Thrombopoietin receptorAliasesMPL, C-CD110, MPLV, THCYT2, TPOR, MPL proto-oncogene, thrombopoietin receptor, THPOR1.00infobox
Thrombopoietin receptorBand1p34.21.00infobox
Thrombopoietin receptorBand4 D2.1|4 54.61 cM1.00infobox
Thrombopoietin receptorBgeetesticle1.00infobox
Thrombopoietin receptorBgeemononuclear cell1.00infobox
Thrombopoietin receptorBgeemonocyte1.00infobox
Thrombopoietin receptorBgeeright frontal lobe1.00infobox
Thrombopoietin receptorBgeebone marrow cell1.00infobox
Thrombopoietin receptorBgeebronchial epithelial cell1.00infobox
Thrombopoietin receptorBgeesural nerve1.00infobox
Thrombopoietin receptorBgeeleft ovary1.00infobox
Thrombopoietin receptorBgeeBrodmann area 91.00infobox
Thrombopoietin receptorBgeeprefrontal cortex1.00infobox
Thrombopoietin receptorBgeeblood1.00infobox
Thrombopoietin receptorBgeegastrula1.00infobox
Thrombopoietin receptorBgeevasculature of trunk1.00infobox
Thrombopoietin receptorBgeetibiofemoral joint1.00infobox
Thrombopoietin receptorBgeeembryo1.00infobox
Thrombopoietin receptorBgeedorsal aorta1.00infobox
Thrombopoietin receptorBgeemorula1.00infobox
Thrombopoietin receptorBgeeyolk sac1.00infobox
Thrombopoietin receptorBgeespleen1.00infobox
Thrombopoietin receptorBioGPSMore reference expression data1.00infobox
Thrombopoietin receptorChr.Chromosome 1 (human)1.00infobox
Thrombopoietin receptorChr.Chromosome 4 (mouse)1.00infobox
Thrombopoietin receptorDatabasesNCBI: entry; OMA: entry1.00infobox
Thrombopoietin receptorEnd43,354,466 bp1.00infobox
Thrombopoietin receptorEnd118,314,710 bp1.00infobox
Thrombopoietin receptorEnsemblENSG000001174001.00infobox
Thrombopoietin receptorEntrez43521.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Thrombopoietin receptor bring nearby vocabulary together. In this analysis, examples include Encoded, Mpl and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Thrombopoietin receptor
    • Encoded
    • Mpl
    • Protein
    • Also
    • Leukemia
    • Myeloproliferative
    • Oncogene
    • Platelet
    • Virus
    • Formation
    • Cd110
    • Thrombopoietin
  • thrombopoietin receptor
    • Encoded
    • Mpl
    • Protein
    • Also
    • Data
    • Function
    • Gene
    • Leukemia
    • Location
    • Myeloproliferative
    • Oncogene
    • Platelet
  • protein
    • Receptor
    • Encoded
    • Cd110
    • Mpl
    • Cluster
    • Data
    • Differentiation
    • Oncogene
    • Virus
    • Thrombopoietin
    • C-mpl
    • Gene
  • leukemia
    • Myeloproliferative
    • Oncogene
    • Virus
    • Mpl
    • Bone
    • Marrow
    • Receptor
    • Thrombopoietin
    • Gene
    • Cluster
    • D2
    • Data
  • function
    • Location
    • Bone
    • Chromosome
    • Marrow
    • Mpl
    • Bp
    • Chr
    • Receptor
    • D2
    • Data
    • End
    • Gene
  • oncogene
    • Virus
    • Bone
    • Marrow
    • Receptor
    • Thrombopoietin
    • Gene
    • D2
    • Data
    • End
    • Function
    • Mouse
    • Protein
  • thrombopoietin
    • Oncogene
    • Platelet
    • Virus
    • Formation
    • Gene
    • Function
    • Location
    • Chromosome
    • Mutations
    • Bp
    • Chr
    • Human
  • myelofibrosis
    • Mutations
    • Gene

Connections between topic areas Semantic bridges

For Thrombopoietin receptor, one of the stronger structural bridges in this analysis connects Thrombopoietin receptor with Discovery. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Thrombopoietin receptorDiscovery · splits 15 ⟂ 5
Thrombopoietin receptorClinical relevance · splits 15 ⟂ 5
Thrombopoietin receptorInteractions · splits 16 ⟂ 4
Thrombopoietin receptorOverview · splits 17 ⟂ 3

Map overview Semantic statistics

Thrombopoietin receptor

Nodes20
Edges19
Triples86
Avg. degree1.9
Density0.1
Components1

Source & methodology

TTTA analyzes the structure around Thrombopoietin receptor to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Discovery, Clinical relevance & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Thrombopoietin receptor · EN edition · Analysis: TopicsToTalkAbout

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