Research any topic before you write.
Find related topics. | Discover entities. | See connections. | Build a topical map.
Runt-related transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) and it is a protein that is encoded by the RUNX1 gene, in humans.
The analysis highlights Characters and Measurement as prominent areas in the source structure around RUNX1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Explore different angles and find fresh ideas to shape your next piece of content.
Search suggestions related to this topic. Open a question to research it further; suggestions are not verified answers.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
You can skip this section if you’re here for content ideas and keyword inspiration.
The extracted context around RUNX1 shows recurring relationship patterns in the source. For example, RUNX1 → ATP binding, calcium ion binding, chondrocyte differentiation, core-binding factor complex, cytosol, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, hematopoietic stem cell proliferation, hemopoiesis, intracellular membrane-bounded organelle, myeloid cell differentiation, negative regulation of CD4-positive, alpha-beta T cell differentiation, negative regulation of gene expression, negative regulation of granulocyte differentiation, negative regulation of transcription by RNA polymerase II, neuron differentiation, nucleoplasm, nucleus Another extracted example is RUNX1 → Although, CBFα, CBFβ, Christiane Nüsslein-Volhard, DNA, DNA-binding, DNAs, Drosophila, Eric, Following, Furthermore, Gergen, Ito, Leukemia, Moloney, Ohki, Purified, RUNX, RUNX1's, RUNX2. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
transcription gene factor binding protein human dna mutations runt leukemia 21 bp also mouse myeloid cells cancer development chromosome role
TTTA extracted 198 structured relationships around RUNX1. Examples in this analysis include RUNX1 → Aliases → RUNX1, AML1, AML1-EVI-1, AMLCR1, CBF2alpha, CBFA2, EVI-1, PEBP2aB, PEBP2alpha, runt related transcription factor 1, RUNX family transcription factor 1 and RUNX1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CMO, 1CO1, 1E50, 1H9D, 1LJM. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| RUNX1 | Aliases | RUNX1, AML1, AML1-EVI-1, AMLCR1, CBF2alpha, CBFA2, EVI-1, PEBP2aB, PEBP2alpha, runt related transcription factor 1, RUNX family transcription factor 1 | 1.00 | infobox |
| RUNX1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CMO, 1CO1, 1E50, 1H9D, 1LJM | 1.00 | infobox |
| RUNX1 | Band | 21q22.12 | 1.00 | infobox |
| RUNX1 | Band | 16 C4|16 53.7 cM | 1.00 | infobox |
| RUNX1 | Bgee | olfactory zone of nasal mucosa | 1.00 | infobox |
| RUNX1 | Bgee | epithelium of bronchus | 1.00 | infobox |
| RUNX1 | Bgee | mucosa of paranasal sinus | 1.00 | infobox |
| RUNX1 | Bgee | bronchial epithelial cell | 1.00 | infobox |
| RUNX1 | Bgee | nasal epithelium | 1.00 | infobox |
| RUNX1 | Bgee | visceral pleura | 1.00 | infobox |
| RUNX1 | Bgee | tendon of biceps brachii | 1.00 | infobox |
| RUNX1 | Bgee | trabecular bone | 1.00 | infobox |
| RUNX1 | Bgee | epithelium of nasopharynx | 1.00 | infobox |
| RUNX1 | Bgee | minor salivary glands | 1.00 | infobox |
| RUNX1 | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| RUNX1 | Bgee | Dermatocranium | 1.00 | infobox |
| RUNX1 | Bgee | membranous bone | 1.00 | infobox |
| RUNX1 | Bgee | decidua | 1.00 | infobox |
| RUNX1 | Bgee | lower jaw | 1.00 | infobox |
| RUNX1 | Bgee | granulocyte | 1.00 | infobox |
| RUNX1 | Bgee | maxilla | 1.00 | infobox |
| RUNX1 | Bgee | mandible | 1.00 | infobox |
| RUNX1 | Bgee | gastrula | 1.00 | infobox |
| RUNX1 | Bgee | cumulus cell | 1.00 | infobox |
| RUNX1 | BioGPS | More reference expression data | 1.00 | infobox |
| RUNX1 | Chr. | Chromosome 21 (human) | 1.00 | infobox |
| RUNX1 | Chr. | Chromosome 16 (mouse) | 1.00 | infobox |
| RUNX1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| RUNX1 | End | 36,004,667 bp | 1.00 | infobox |
| RUNX1 | End | 92,623,037 bp | 1.00 | infobox |
The concept neighborhoods around RUNX1 bring nearby vocabulary together. In this analysis, examples include Transcription, Binding and Mutations. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For RUNX1, one of the stronger structural bridges in this analysis connects RUNX1 with Gene and protein. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around RUNX1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Characters & Measurement, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — RUNX1 · EN edition · Analysis: TopicsToTalkAbout
