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Bromodomain-containing protein 4 is a protein that in humans is encoded by the BRD4 gene.
The analysis highlights Interactions, Structure and Function as prominent areas in the source structure around BRD4.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around BRD4 shows recurring relationship patterns in the source. For example, BRD4 → cellular response to DNA damage stimulus, chromatin binding, chromatin organization, chromatin remodeling, chromosome, condensed nuclear chromosome, cytosol, enzyme binding, lysine-acetylated histone binding, negative regulation of DNA damage checkpoint, nucleoplasm, nucleus, P-TEFb complex binding, p53 binding, positive regulation of G2/M transition of mitotic cell cycle, positive regulation of histone H3-K36 trimethylation, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of transcription by RNA polymerase II, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription, DNA-templated Another extracted example is BRD4 → aortic valve, ascending aorta, blood, buccal mucosa cell, cardia, cumulus cell, genital tubercle, internal carotid artery, internal globus pallidus, nipple, pylorus, renal medulla, Rostral migratory stream, secondary oocyte, sural nerve, tail of embryo, tendon of biceps brachii, vena cava, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene human bp domain chromosome bet chr band also 19 family protein location two c-terminal bromodomains p-tefb 15 members mouse
TTTA extracted 121 structured relationships around BRD4. Examples in this analysis include BRD4 → Aliases → BRD4, CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4 and BRD4 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2I8N, 2LSP, 2MJV, 2OSS, 2OUO, 2YEL, 2YEM, 3MXF, 3P5O, 3SVF, 3SVG, 3U5J, 3U5K, 3U5L, 3UVW, 3UVX, 3UVY, 3UW9,…. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| BRD4 | Aliases | BRD4, CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4 | 1.00 | infobox |
| BRD4 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2I8N, 2LSP, 2MJV, 2OSS, 2OUO, 2YEL, 2YEM, 3MXF, 3P5O, 3SVF, 3SVG, 3U5J, 3U5K, 3U5L, 3UVW, 3UVX, 3UVY, 3UW9,… | 1.00 | infobox |
| BRD4 | Band | 19p13.12 | 1.00 | infobox |
| BRD4 | Band | 17 B1|17 17.39 cM | 1.00 | infobox |
| BRD4 | Bgee | buccal mucosa cell | 1.00 | infobox |
| BRD4 | Bgee | sural nerve | 1.00 | infobox |
| BRD4 | Bgee | tendon of biceps brachii | 1.00 | infobox |
| BRD4 | Bgee | nipple | 1.00 | infobox |
| BRD4 | Bgee | internal globus pallidus | 1.00 | infobox |
| BRD4 | Bgee | pylorus | 1.00 | infobox |
| BRD4 | Bgee | secondary oocyte | 1.00 | infobox |
| BRD4 | Bgee | cardia | 1.00 | infobox |
| BRD4 | Bgee | renal medulla | 1.00 | infobox |
| BRD4 | Bgee | vena cava | 1.00 | infobox |
| BRD4 | Bgee | Rostral migratory stream | 1.00 | infobox |
| BRD4 | Bgee | genital tubercle | 1.00 | infobox |
| BRD4 | Bgee | tail of embryo | 1.00 | infobox |
| BRD4 | Bgee | cumulus cell | 1.00 | infobox |
| BRD4 | Bgee | blood | 1.00 | infobox |
| BRD4 | Bgee | zygote | 1.00 | infobox |
| BRD4 | Bgee | internal carotid artery | 1.00 | infobox |
| BRD4 | Bgee | ascending aorta | 1.00 | infobox |
| BRD4 | Bgee | aortic valve | 1.00 | infobox |
| BRD4 | BioGPS | More reference expression data | 1.00 | infobox |
| BRD4 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| BRD4 | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| BRD4 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| BRD4 | End | 15,332,545 bp | 1.00 | infobox |
| BRD4 | End | 32,284,722 bp | 1.00 | infobox |
| BRD4 | Ensembl | ENSG00000141867 | 1.00 | infobox |
The concept neighborhoods around BRD4 bring nearby vocabulary together. In this analysis, examples include Gene, Also and Domain. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For BRD4, one of the stronger structural bridges in this analysis connects BRD4 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around BRD4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Structure & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — BRD4 · EN edition · Analysis: TopicsToTalkAbout