Interactive map loads when it comes into view.
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
Research this topic
Explore the main themes, entities and connections around BRD4. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Explore this topic
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
Interactions
13 related topics
Structure
5 related topics
Function
5 related topics
Role in cancer
5 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- Aliases
- BRD4, CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2I8N, 2LSP, 2MJV, 2OSS, 2OUO, 2YEL, 2YEM, 3MXF, 3P5O, 3SVF, 3SVG, 3U5J, 3U5K, 3U5L, 3UVW, 3UVX, 3UVY, 3UW9,…
- Band
- 19p13.12 · 17 B1|17 17.39 cM
- Bgee
- buccal mucosa cell · sural nerve · tendon of biceps brachii · nipple · internal globus pallidus
- BioGPS
- More reference expression data
- Chr.
- Chromosome 19 (human) · Chromosome 17 (mouse)
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
Structure
- Alpha-helices
- Loops Turn (biochemistry)
- Gene transcription
- P-TEFb
- RNA polymerase II
Function
- Serine/threonine kinase
- Sequence motif
- Chromatin
- Translocation Chromosomal translocation
- NUT midline carcinoma
Role in cancer
- Myc
- Multiple myeloma
- Acute myelogenous leukemia
- Acute lymphoblastic leukaemia. Acute lymphoblastic leukemia
- BET inhibitors
Interactions
- Interact Protein-protein interaction
- GATA1
- JMJD6
- RFC2
- RFC3
- RFC1
- RFC4
- RFC5
- Twist Twist transcription factor
- NF-κB
- Apabetalone
- Atherosclerosis
- Cardiovascular disease
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.BRD4
Nodes42
Edges41
Triples121
Avg. degree1.95
Density0.047619
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
BRD4
Top relations
Gene ontology · 31
BRD4 → cellular response to DNA damage stimulus, chromatin binding, chromatin organization, chromatin remodeling, chromosome, condensed nuclear chromosome, cytosol, enzyme binding, lysine-acetylated histone binding, negative regulation of DNA damage checkpoint, nucleoplasm, nucleus, P-TEFb complex binding, p53 binding, positive regulation of G2/M transition of mitotic cell cycle, positive regulation of histone H3-K36 trimethylation, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of transcription by RNA polymerase II, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription, DNA-templated
Bgee · 19
BRD4 → aortic valve, ascending aorta, blood, buccal mucosa cell, cardia, cumulus cell, genital tubercle, internal carotid artery, internal globus pallidus, nipple, pylorus, renal medulla, Rostral migratory stream, secondary oocyte, sural nerve, tail of embryo, tendon of biceps brachii, vena cava, zygote
RNA expression pattern · 19
BRD4 → aortic valve, ascending aorta, blood, buccal mucosa cell, cardia, cumulus cell, genital tubercle, internal carotid artery, internal globus pallidus, nipple, pylorus, renal medulla, Rostral migratory stream, secondary oocyte, sural nerve, tail of embryo, tendon of biceps brachii, vena cava, zygote
related to Interactions · 13
BRD4 → CTD, GATA1, II, JMJD6, Notably, P-TEFb, PID, RFC1, RFC2, RFC3, RFC4, RFC5, RNA
related to Structure · 8
BRD4 → BD1, BD2, II, P-TEFb, RNA, The, The C-terminal, The ET
related to Role in cancer · 4
BRD4 → BET, Most, Myc, NUT
Band · 2
BRD4 → 17 B1|17 17.39 cM, 19p13.12
Chr. · 2
BRD4 → Chromosome 17 (mouse), Chromosome 19 (human)
End · 2
BRD4 → 15,332,545 bp, 32,284,722 bp
is a · 2
BRD4 → major target of BET inhibitors, member of the BET
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
gene human bp domain chromosome bet chr band also 19 family protein location two c-terminal bromodomains p-tefb 15 members mouse
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| BRD4 | Aliases | BRD4, CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4 | 1.00 | infobox |
| BRD4 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2I8N, 2LSP, 2MJV, 2OSS, 2OUO, 2YEL, 2YEM, 3MXF, 3P5O, 3SVF, 3SVG, 3U5J, 3U5K, 3U5L, 3UVW, 3UVX, 3UVY, 3UW9,… | 1.00 | infobox |
| BRD4 | Band | 19p13.12 | 1.00 | infobox |
| BRD4 | Band | 17 B1|17 17.39 cM | 1.00 | infobox |
| BRD4 | Bgee | buccal mucosa cell | 1.00 | infobox |
| BRD4 | Bgee | sural nerve | 1.00 | infobox |
| BRD4 | Bgee | tendon of biceps brachii | 1.00 | infobox |
| BRD4 | Bgee | nipple | 1.00 | infobox |
| BRD4 | Bgee | internal globus pallidus | 1.00 | infobox |
| BRD4 | Bgee | pylorus | 1.00 | infobox |
| BRD4 | Bgee | secondary oocyte | 1.00 | infobox |
| BRD4 | Bgee | cardia | 1.00 | infobox |
| BRD4 | Bgee | renal medulla | 1.00 | infobox |
| BRD4 | Bgee | vena cava | 1.00 | infobox |
| BRD4 | Bgee | Rostral migratory stream | 1.00 | infobox |
| BRD4 | Bgee | genital tubercle | 1.00 | infobox |
| BRD4 | Bgee | tail of embryo | 1.00 | infobox |
| BRD4 | Bgee | cumulus cell | 1.00 | infobox |
| BRD4 | Bgee | blood | 1.00 | infobox |
| BRD4 | Bgee | zygote | 1.00 | infobox |
| BRD4 | Bgee | internal carotid artery | 1.00 | infobox |
| BRD4 | Bgee | ascending aorta | 1.00 | infobox |
| BRD4 | Bgee | aortic valve | 1.00 | infobox |
| BRD4 | BioGPS | More reference expression data | 1.00 | infobox |
| BRD4 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| BRD4 | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| BRD4 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| BRD4 | End | 15,332,545 bp | 1.00 | infobox |
| BRD4 | End | 32,284,722 bp | 1.00 | infobox |
| BRD4 | Ensembl | ENSG00000141867 | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.