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Mitogen-activated protein kinase 8 (also known as JNK1) is a ubiquitous enzyme that in humans is encoded by the MAPK8 gene.
The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around MAPK8.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around MAPK8 shows recurring relationship patterns in the source. For example, MAPK8 → ATP binding, axon, basal dendrite, cellular response to amino acid starvation, cellular response to cadmium ion, cellular response to cytokine stimulus, cellular response to lipopolysaccharide, cellular response to mechanical stimulus, cellular response to organic substance, cellular response to reactive oxygen species, cytoplasm, cytosol, enzyme binding, Fc-epsilon receptor signaling pathway, histone deacetylase binding, histone deacetylase regulator activity, intracellular signal transduction, JNK cascade, JUN kinase activity, JUN phosphorylation Another extracted example is MAPK8 → Achilles tendon, barrel cortex, buccal mucosa cell, epithelium of colon, gallbladder, ganglionic eminence, genital tubercle, internal globus pallidus, islet of Langerhans, perirhinal cortex, piriform cortex, primary oocyte, secondary oocyte, stromal cell of endometrium, superior cervical ganglion, tendon of biceps brachii, ventricular zone, visual cortex, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
kinase gene bp chr human band protein chromosome 10 enzyme mouse cell map transcription location jnk apoptosis involved factor mitogen-activated
TTTA extracted 147 structured relationships around MAPK8. Examples in this analysis include MAPK8 → 2.7.11.24 → ↗ and MAPK8 → Aliases → MAPK8, Mapk8, AI849689, JNK, JNK1, Prkm8, SAPK1, JNK-46, JNK1A2, JNK21B1/2, SAPK1c, mitogen-activated protein kinase 8. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MAPK8 | 2.7.11.24 | ↗ | 1.00 | infobox |
| MAPK8 | Aliases | MAPK8, Mapk8, AI849689, JNK, JNK1, Prkm8, SAPK1, JNK-46, JNK1A2, JNK21B1/2, SAPK1c, mitogen-activated protein kinase 8 | 1.00 | infobox |
| MAPK8 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UKH, 1UKI, 2G01, 2GMX, 2H96, 2NO3, 2XRW, 2XS0, 3ELJ, 3O17, 3O2M, 3PZE, 3V3V, 3VUD, 3VUG, 3VUH, 3VUI, 3VUK,… | 1.00 | infobox |
| MAPK8 | Band | 10q11.22 | 1.00 | infobox |
| MAPK8 | Band | 14|14 B | 1.00 | infobox |
| MAPK8 | Bgee | ganglionic eminence | 1.00 | infobox |
| MAPK8 | Bgee | tendon of biceps brachii | 1.00 | infobox |
| MAPK8 | Bgee | Achilles tendon | 1.00 | infobox |
| MAPK8 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| MAPK8 | Bgee | buccal mucosa cell | 1.00 | infobox |
| MAPK8 | Bgee | ventricular zone | 1.00 | infobox |
| MAPK8 | Bgee | islet of Langerhans | 1.00 | infobox |
| MAPK8 | Bgee | internal globus pallidus | 1.00 | infobox |
| MAPK8 | Bgee | gallbladder | 1.00 | infobox |
| MAPK8 | Bgee | epithelium of colon | 1.00 | infobox |
| MAPK8 | Bgee | zygote | 1.00 | infobox |
| MAPK8 | Bgee | secondary oocyte | 1.00 | infobox |
| MAPK8 | Bgee | primary oocyte | 1.00 | infobox |
| MAPK8 | Bgee | barrel cortex | 1.00 | infobox |
| MAPK8 | Bgee | superior cervical ganglion | 1.00 | infobox |
| MAPK8 | Bgee | perirhinal cortex | 1.00 | infobox |
| MAPK8 | Bgee | visual cortex | 1.00 | infobox |
| MAPK8 | Bgee | genital tubercle | 1.00 | infobox |
| MAPK8 | Bgee | piriform cortex | 1.00 | infobox |
| MAPK8 | BioGPS | More reference expression data | 1.00 | infobox |
| MAPK8 | Chr. | Chromosome 10 (human) | 1.00 | infobox |
| MAPK8 | Chr. | Chromosome 14 (mouse) | 1.00 | infobox |
| MAPK8 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MAPK8 | End | 48,439,360 bp | 1.00 | infobox |
| MAPK8 | End | 33,169,115 bp | 1.00 | infobox |
The concept neighborhoods around MAPK8 bring nearby vocabulary together. In this analysis, examples include Protein, Activity and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MAPK8, one of the stronger structural bridges in this analysis connects MAPK8 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MAPK8 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MAPK8 · EN edition · Analysis: TopicsToTalkAbout