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P73

p73 is a protein related to the p53 tumor protein. Because of its structural resemblance to p53, it has also been considered a tumor suppressor. It is involved in cell cycle regulation, and induction of apoptosis. Like p53, p73 is characterized by the presence of different isoforms of the protein. This is explained by splice variants, and an alternative…

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Aliases
TP73, P73, tumor protein p73, CILD47
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GUQ, 1COK, 1DXS, 2KBY, 2MPS, 2WQI, 2WQJ, 2WTT, 2XWC, 3VD0, 3VD1, 3VD2, 4A63, 4G82, 4G83, 4GUO
Band
1p36.32 · 4 E2|4 83.79 cM
Bgee
right uterine tube · olfactory zone of nasal mucosa · bronchial epithelial cell · cerebellar hemisphere · right hemisphere of cerebellum
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)

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P73

Nodes10
Edges9
Triples132
Avg. degree1.8
Density0.2
Components1

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P73

Top relations

Gene ontology · 59
P73 → apoptotic process, cell cycle, cell junction, cellular response to DNA damage stimulus, cellular response to UV, chromatin, chromatin binding, cytoplasm, cytosol, damaged DNA binding, DNA binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA mismatch repair, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, Golgi apparatus, identical protein binding, intracellular membrane-bounded organelle, intrinsic apoptotic signaling pathway in response to DNA damage
Bgee · 20
P73 → bone marrow cell, bronchial epithelial cell, cerebellar hemisphere, choroid plexus of fourth ventricle, choroidal fissure, embryo, Epithelium of choroid plexus, Jacobson's organ, lip, mandibular molars, minor salivary glands, mucosa of esophagus, olfactory zone of nasal mucosa, primary oocyte, right hemisphere of cerebellum, right uterine tube, secondary oocyte, skin of abdomen, skin of leg, zygote
RNA expression pattern · 20
P73 → bone marrow cell, bronchial epithelial cell, cerebellar hemisphere, choroid plexus of fourth ventricle, choroidal fissure, embryo, Epithelium of choroid plexus, Jacobson's organ, lip, mandibular molars, minor salivary glands, mucosa of esophagus, olfactory zone of nasal mucosa, primary oocyte, right hemisphere of cerebellum, right uterine tube, secondary oocyte, skin of abdomen, skin of leg, zygote
related to External links · 9
P73 → Medicine Medical Subject Headings, MeSH, National Library, O15350, Overview, PDB, PDBe-KB, Tumor, UniProt
Band · 2
P73 → 1p36.32, 4 E2|4 83.79 cM
Chr. · 2
P73 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
P73 → 154,224,665 bp, 3,736,201 bp
Aliases · 1
P73 → TP73, P73, tumor protein p73, CILD47
Available structures · 1
P73 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GUQ, 1COK, 1DXS, 2KBY, 2MPS, 2WQI, 2WQJ, 2WTT, 2XWC, 3VD0, 3VD1, 3VD2, 4A63, 4G82, 4G83, 4GUO
BioGPS · 1
P73 → More reference expression data

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Important terminology

p53 tumor protein suppressor cell gene human apoptosis bp tp73 function chromosome also variants chr cycle expression band dna found

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
P73AliasesTP73, P73, tumor protein p73, CILD471.00infobox
P73Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GUQ, 1COK, 1DXS, 2KBY, 2MPS, 2WQI, 2WQJ, 2WTT, 2XWC, 3VD0, 3VD1, 3VD2, 4A63, 4G82, 4G83, 4GUO1.00infobox
P73Band1p36.321.00infobox
P73Band4 E2|4 83.79 cM1.00infobox
P73Bgeeright uterine tube1.00infobox
P73Bgeeolfactory zone of nasal mucosa1.00infobox
P73Bgeebronchial epithelial cell1.00infobox
P73Bgeecerebellar hemisphere1.00infobox
P73Bgeeright hemisphere of cerebellum1.00infobox
P73Bgeeskin of leg1.00infobox
P73Bgeeskin of abdomen1.00infobox
P73Bgeemucosa of esophagus1.00infobox
P73Bgeeminor salivary glands1.00infobox
P73Bgeebone marrow cell1.00infobox
P73Bgeechoroidal fissure1.00infobox
P73Bgeechoroid plexus of fourth ventricle1.00infobox
P73Bgeezygote1.00infobox
P73Bgeelip1.00infobox
P73Bgeesecondary oocyte1.00infobox
P73BgeeJacobson's organ1.00infobox
P73Bgeemandibular molars1.00infobox
P73BgeeEpithelium of choroid plexus1.00infobox
P73Bgeeembryo1.00infobox
P73Bgeeprimary oocyte1.00infobox
P73BioGPSMore reference expression data1.00infobox
P73Chr.Chromosome 1 (human)1.00infobox
P73Chr.Chromosome 4 (mouse)1.00infobox
P73DatabasesNCBI: entry; OMA: entry1.00infobox
P73End3,736,201 bp1.00infobox
P73End154,224,665 bp1.00infobox

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