P73

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P73 topic overview

The analysis highlights Standards and Overview as prominent areas in the source structure around P73.

Related topics: 8
Source areas: 1
Connected nodes: 9
Extracted relationships: 132
Concept neighborhoods: 8
Bridge connections: 9

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 8 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: TP73, P73, tumor protein p73, CILD47
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GUQ, 1COK, 1DXS, 2KBY, 2MPS, 2WQI, 2WQJ, 2WTT, 2XWC, 3VD0, 3VD1, 3VD2, 4A63, 4G82, 4G83, 4GUO
Band: 1p36.32 · 4 E2|4 83.79 cM
Bgee: right uterine tube · olfactory zone of nasal mucosa · bronchial epithelial cell · cerebellar hemisphere · right hemisphere of cerebellum
BioGPS: More reference expression data
Chr.: Chromosome 1 (human) · Chromosome 4 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

P53
Tumor suppressor Tumor suppressor gene
Cell cycle
Apoptosis
Splice variants Splice variant
Promoter Promoter (biology)
DNA
N-terminus

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How P73 connects Entity context

The extracted context around P73 shows recurring relationship patterns in the source. For example, P73 → apoptotic process, cell cycle, cell junction, cellular response to DNA damage stimulus, cellular response to UV, chromatin, chromatin binding, cytoplasm, cytosol, damaged DNA binding, DNA binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA mismatch repair, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, Golgi apparatus, identical protein binding, intracellular membrane-bounded organelle, intrinsic apoptotic signaling pathway in response to DNA damage Another extracted example is P73 → bone marrow cell, bronchial epithelial cell, cerebellar hemisphere, choroid plexus of fourth ventricle, choroidal fissure, embryo, Epithelium of choroid plexus, Jacobson's organ, lip, mandibular molars, minor salivary glands, mucosa of esophagus, olfactory zone of nasal mucosa, primary oocyte, right hemisphere of cerebellum, right uterine tube, secondary oocyte, skin of abdomen, skin of leg, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 59

P73 → apoptotic process, cell cycle, cell junction, cellular response to DNA damage stimulus, cellular response to UV, chromatin, chromatin binding, cytoplasm, cytosol, damaged DNA binding, DNA binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA mismatch repair, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, Golgi apparatus, identical protein binding, intracellular membrane-bounded organelle, intrinsic apoptotic signaling pathway in response to DNA damage

Bgee · 20

P73 → bone marrow cell, bronchial epithelial cell, cerebellar hemisphere, choroid plexus of fourth ventricle, choroidal fissure, embryo, Epithelium of choroid plexus, Jacobson's organ, lip, mandibular molars, minor salivary glands, mucosa of esophagus, olfactory zone of nasal mucosa, primary oocyte, right hemisphere of cerebellum, right uterine tube, secondary oocyte, skin of abdomen, skin of leg, zygote

RNA expression pattern · 20

related to External links · 9

P73 → Medicine Medical Subject Headings, MeSH, National Library, O15350, Overview, PDB, PDBe-KB, Tumor, UniProt

Band · 2

P73 → 1p36.32, 4 E2|4 83.79 cM

Chr. · 2

P73 → Chromosome 1 (human), Chromosome 4 (mouse)

End · 2

P73 → 154,224,665 bp, 3,736,201 bp

Aliases · 1

P73 → TP73, P73, tumor protein p73, CILD47

Available structures · 1

P73 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GUQ, 1COK, 1DXS, 2KBY, 2MPS, 2WQI, 2WQJ, 2WTT, 2XWC, 3VD0, 3VD1, 3VD2, 4A63, 4G82, 4G83, 4GUO

BioGPS · 1

P73 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

p53 tumor protein suppressor cell gene human apoptosis bp tp73 function chromosome also variants chr cycle expression band dna found

P73 relationships Subject–Predicate–Object triples

TTTA extracted 132 structured relationships around P73. Examples in this analysis include P73 → Aliases → TP73, P73, tumor protein p73, CILD47 and P73 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GUQ, 1COK, 1DXS, 2KBY, 2MPS, 2WQI, 2WQJ, 2WTT, 2XWC, 3VD0, 3VD1, 3VD2, 4A63, 4G82, 4G83, 4GUO. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
P73	Aliases	TP73, P73, tumor protein p73, CILD47	1.00	infobox
P73	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GUQ, 1COK, 1DXS, 2KBY, 2MPS, 2WQI, 2WQJ, 2WTT, 2XWC, 3VD0, 3VD1, 3VD2, 4A63, 4G82, 4G83, 4GUO	1.00	infobox
P73	Band	1p36.32	1.00	infobox
P73	Band	4 E2\|4 83.79 cM	1.00	infobox
P73	Bgee	right uterine tube	1.00	infobox
P73	Bgee	olfactory zone of nasal mucosa	1.00	infobox
P73	Bgee	bronchial epithelial cell	1.00	infobox
P73	Bgee	cerebellar hemisphere	1.00	infobox
P73	Bgee	right hemisphere of cerebellum	1.00	infobox
P73	Bgee	skin of leg	1.00	infobox
P73	Bgee	skin of abdomen	1.00	infobox
P73	Bgee	mucosa of esophagus	1.00	infobox
P73	Bgee	minor salivary glands	1.00	infobox
P73	Bgee	bone marrow cell	1.00	infobox
P73	Bgee	choroidal fissure	1.00	infobox
P73	Bgee	choroid plexus of fourth ventricle	1.00	infobox
P73	Bgee	zygote	1.00	infobox
P73	Bgee	lip	1.00	infobox
P73	Bgee	secondary oocyte	1.00	infobox
P73	Bgee	Jacobson's organ	1.00	infobox
P73	Bgee	mandibular molars	1.00	infobox
P73	Bgee	Epithelium of choroid plexus	1.00	infobox
P73	Bgee	embryo	1.00	infobox
P73	Bgee	primary oocyte	1.00	infobox
P73	BioGPS	More reference expression data	1.00	infobox
P73	Chr.	Chromosome 1 (human)	1.00	infobox
P73	Chr.	Chromosome 4 (mouse)	1.00	infobox
P73	Databases	NCBI: entry; OMA: entry	1.00	infobox
P73	End	3,736,201 bp	1.00	infobox
P73	End	154,224,665 bp	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around P73 bring nearby vocabulary together. In this analysis, examples include P53, Protein and Tumor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

P73
- P53
- Protein
- Tumor
- Gene
- Expression
- Function
- Suppressor
- Cellular
- Dna
- Also
- Apoptosis
- Cycle
p73
- P53
- Protein
- Tumor
- Gene
- Expression
- Function
- Suppressor
- Cellular
- Dna
- Also
- Apoptosis
- Cycle
p53
- Protein
- P73
- Tumor
- Suppressor
- Also
- Apoptosis
- Function
- Cell
- Gene
- Arrest
- Known
- Like
cell cycle
- Cycle
- Involved
- Regulation
- Induces
- Dna
- Apoptosis
- Expression
- Arrest
- Over-expression
- P53
- Protein
- Cells
dna
- Involved
- Regulation
- Expression
- Tp73
- Gene
- Induces
- Known
- Over-expression
- Sequence
- Protein
- Cells
- Cellular
tumor suppressor
- Tumor
- Sequence
- Encodes
- Tp73
- Gene
- Locus
- Human
- Arrest
- Induces
- Known
- Many
- Dna
splice variants
- Different
- Known
- Like
- Normal
- Sequence
- Cells
- Dna
- Found
- Also
- Tp73
- P53
- P73
apoptosis
- Arrest
- Cycle
- Cell
- P53
- Induces
- Over-expression
- Cells
- Involved
- Regulation
- Function
- P73
- Suppressor

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the P73 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

P73

Nodes10

Edges9

Triples132

Avg. degree1.8

Density0.2

Components1

Source & methodology

TTTA analyzes the structure around P73 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — P73 · EN edition · Analysis: TopicsToTalkAbout