DNA (cytosine-5)-methyltransferase 3A

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Explore the main themes, entities and connections around DNA (cytosine-5)-methyltransferase 3A. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Protein structure

DNMT3L N-terminal GATA-like zinc finger PHD finger Alpha helix Histone H3

10 related topics

Interactions

Interact HDAC1 Myc PIAS1 PIAS2

8 related topics

Overview

Enzyme DNA methylation Gene DNA methyltransferase DNMT1

17 related topics

Gene

Exons Homology Murine Nucleus accumbens shell Cocaine

5 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.1.1.37: ↗
Aliases: DNMT3A, DNMT3A2, M.HsaIIIA, TBRS, DNA (cytosine-5-)-methyltransferase 3 alpha, DNA methyltransferase 3 alpha, HESJAS
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4U7T, 4QBR, 4U7P, 4QBS, 3A1B, 3LLR, 4QBQ, 3SVM, 3A1A, 2QRV
Band: 2p23.3 · 12|12 A1.1
Bgee: sural nerve · ganglionic eminence · ventricular zone · Skeletal muscle tissue of biceps brachii · oocyte
BioGPS: More reference expression data

Topics to explore

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Overview

Enzyme
DNA methylation
Gene
DNA methyltransferase
DNMT1
DNMT3B
Epigenetic Epigenetics
Cellular differentiation
Embryonic development Embryogenesis
Transcriptional regulation
Heterochromatin
X-inactivation
Imprinting Genomic imprinting
Clonal hematopoiesis
Hematopoietic stem cells (HSCs) Hematopoietic stem cell
Cell progenitors Progenitor cell
Blood cells Blood cell

Gene

Exons Exon shuffling
Homology Homology (biology)
Murine Murinae
Nucleus accumbens shell Nucleus accumbens
Cocaine

Protein structure

DNMT3L
N-terminal GATA-like zinc finger GATA zinc finger
PHD finger
Alpha helix
Histone H3
Prokaryotes Prokaryote
Methyl group
CpG site
Nucleosome
Linker DNA

Function

Contextual fear conditioning Fear conditioning

Animal studies

Ctnb1 Beta-catenin

Clinical relevance

Interactions

Interact Protein-protein interaction
HDAC1
Myc
PIAS1
PIAS2 Protein inhibitor of activated STAT2
SUV39H1
UBE2I
ZNF238

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes55

Edges54

Triples124

Avg. degree1.96

Density0.036364

Components1

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DNA (cytosine-5)-methyltransferase 3A

Top relations

Gene ontology · 50

DNA (cytosine-5)-methyltransferase 3A → ageing, C-5 methylation of cytosine, cellular response to amino acid stimulus, cellular response to ethanol, cellular response to hypoxia, chromatin binding, chromatin organization, chromosome, centromeric region, cytoplasm, DNA (cytosine-5-)-methyltransferase activity, DNA binding, DNA methylation, DNA methylation involved in embryo development, DNA methylation involved in gamete generation, DNA methylation on cytosine, DNA methylation-dependent heterochromatin assembly, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-methyltransferase activity, euchromatin, hepatocyte apoptotic process

Bgee · 20

DNA (cytosine-5)-methyltransferase 3A → ejaculatory duct, epithelium of urethra, female urethra, ganglionic eminence, genital tubercle, lamina propria of urethra, left ovary, male urethra, medullary collecting duct, muscle layer of urethra, muscle of thigh, oocyte, placenta, right ovary, Rostral migratory stream, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sural nerve, tail of embryo, ventricular zone

RNA expression pattern · 20

Band · 2

DNA (cytosine-5)-methyltransferase 3A → 12|12 A1.1, 2p23.3

Chr. · 2

DNA (cytosine-5)-methyltransferase 3A → Chromosome 12 (mouse), Chromosome 2 (human)

End · 2

DNA (cytosine-5)-methyltransferase 3A → 25,342,590 bp, 3,964,443 bp

2.1.1.37 · 1

DNA (cytosine-5)-methyltransferase 3A → ↗

Aliases · 1

DNA (cytosine-5)-methyltransferase 3A → DNMT3A, DNMT3A2, M.HsaIIIA, TBRS, DNA (cytosine-5-)-methyltransferase 3 alpha, DNA methyltransferase 3 alpha, HESJAS

Available structures · 1

DNA (cytosine-5)-methyltransferase 3A → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4U7T, 4QBR, 4U7P, 4QBS, 3A1B, 3LLR, 4QBQ, 3SVM, 3A1A, 2QRV

BioGPS · 1

DNA (cytosine-5)-methyltransferase 3A → More reference expression data

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

dnmt3a dna methylation protein gene dnmt3a2 de novo human accessory methyltransferase domain bp dnmt3b enzyme catalytic dnmt1 chr band function

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
DNA (cytosine-5)-methyltransferase 3A	2.1.1.37	↗	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Aliases	DNMT3A, DNMT3A2, M.HsaIIIA, TBRS, DNA (cytosine-5-)-methyltransferase 3 alpha, DNA methyltransferase 3 alpha, HESJAS	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4U7T, 4QBR, 4U7P, 4QBS, 3A1B, 3LLR, 4QBQ, 3SVM, 3A1A, 2QRV	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Band	2p23.3	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Band	12\|12 A1.1	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	sural nerve	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	ganglionic eminence	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	ventricular zone	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	Skeletal muscle tissue of biceps brachii	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	oocyte	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	placenta	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	right ovary	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	muscle of thigh	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	Skeletal muscle tissue of rectus abdominis	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	left ovary	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	tail of embryo	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	male urethra	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	lamina propria of urethra	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	ejaculatory duct	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	genital tubercle	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	epithelium of urethra	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	female urethra	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	medullary collecting duct	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	muscle layer of urethra	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Bgee	Rostral migratory stream	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	BioGPS	More reference expression data	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Chr.	Chromosome 2 (human)	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Chr.	Chromosome 12 (mouse)	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	Databases	NCBI: entry; OMA: entry	1.00	infobox
DNA (cytosine-5)-methyltransferase 3A	End	25,342,590 bp	1.00	infobox

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