Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

GTF2I: Interactions, Function & Overview

General transcription factor II-I is a protein that in humans is encoded by the GTF2I gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

GTF2I topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around GTF2I.

Related topics
13
Source areas
3
Connected nodes
16
Extracted relationships
106
Concept neighborhoods
11
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 9 topics
Function · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GTF2I, BAP135, BTKAP1, DIWS, GTFII-I, IB291, SPIN, TFII-I, WBS, WBSCR6, general transcription factor IIi
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2D9B, 2DN4, 2ED2, 2EJE
Band
7q11.23 · 5 G2|5 74.48 cM
Bgee
ganglionic eminence · epithelium of colon · sural nerve · ventricular zone · right uterine tube
BioGPS
n/a
Chr.
Chromosome 7 (human) · Chromosome 5 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GTF2I connects Entity context

The extracted context around GTF2I shows recurring relationship patterns in the source. For example, GTF2I → body of pancreas, ciliary body, epithelium of colon, ganglionic eminence, left lobe of thyroid gland, medullary collecting duct, molar, primitive streak, renal corpuscle, retinal pigment epithelium, right adrenal cortex, right lobe of thyroid gland, right ovary, right uterine tube, spermatocyte, superior surface of tongue, sural nerve, utricle, ventricular zone, vestibular sensory epithelium Another extracted example is GTF2I → cell projection, cytoplasm, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, membrane, mitogen-activated protein kinase binding, negative regulation of angiogenesis, negative regulation of cytosolic calcium ion concentration, nucleoplasm, nucleus, protein binding, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, signal transduction, soma, transcription by RNA polymerase II, transcription initiation from RNA polymerase II promoter, transcription, DNA-templated, transition between slow and fast fiber. Use these groups to spot repeated connection types before inspecting the individual relationships.

GTF2I

Top relations

Bgee · 20
GTF2I → body of pancreas, ciliary body, epithelium of colon, ganglionic eminence, left lobe of thyroid gland, medullary collecting duct, molar, primitive streak, renal corpuscle, retinal pigment epithelium, right adrenal cortex, right lobe of thyroid gland, right ovary, right uterine tube, spermatocyte, superior surface of tongue, sural nerve, utricle, ventricular zone, vestibular sensory epithelium
Gene ontology · 20
GTF2I → cell projection, cytoplasm, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, membrane, mitogen-activated protein kinase binding, negative regulation of angiogenesis, negative regulation of cytosolic calcium ion concentration, nucleoplasm, nucleus, protein binding, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, signal transduction, soma, transcription by RNA polymerase II, transcription initiation from RNA polymerase II promoter, transcription, DNA-templated, transition between slow and fast fiber
RNA expression pattern · 20
GTF2I → body of pancreas, ciliary body, epithelium of colon, ganglionic eminence, left lobe of thyroid gland, medullary collecting duct, molar, primitive streak, renal corpuscle, retinal pigment epithelium, right adrenal cortex, right lobe of thyroid gland, right ovary, right uterine tube, spermatocyte, superior surface of tongue, sural nerve, utricle, ventricular zone, vestibular sensory epithelium
related to Function · 10
GTF2I → Haploinsuffiency, It, Single, SNP, TFII-I, The, This, Thymomas, UTR, Williams-Beuren
related to Interactions · 7
GTF2I → Bruton's, HDAC3, Histone, MAPK3, Myc, PRKG1, Serum
related to External links · 6
GTF2I → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library
Band · 2
GTF2I → 5 G2|5 74.48 cM, 7q11.23
Chr. · 2
GTF2I → Chromosome 5 (mouse), Chromosome 7 (human)
End · 2
GTF2I → 134,314,760 bp, 74,760,692 bp
Aliases · 1
GTF2I → GTF2I, BAP135, BTKAP1, DIWS, GTFII-I, IB291, SPIN, TFII-I, WBS, WBSCR6, general transcription factor IIi

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene human bp chr band chromosome transcription factor protein location 760 mouse 7q11 23 general function external humans search 692

GTF2I relationships Subject–Predicate–Object triples

TTTA extracted 106 structured relationships around GTF2I. Examples in this analysis include GTF2I → Aliases → GTF2I, BAP135, BTKAP1, DIWS, GTFII-I, IB291, SPIN, TFII-I, WBS, WBSCR6, general transcription factor IIi and GTF2I → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2D9B, 2DN4, 2ED2, 2EJE. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GTF2IAliasesGTF2I, BAP135, BTKAP1, DIWS, GTFII-I, IB291, SPIN, TFII-I, WBS, WBSCR6, general transcription factor IIi1.00infobox
GTF2IAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2D9B, 2DN4, 2ED2, 2EJE1.00infobox
GTF2IBand7q11.231.00infobox
GTF2IBand5 G2|5 74.48 cM1.00infobox
GTF2IBgeeganglionic eminence1.00infobox
GTF2IBgeeepithelium of colon1.00infobox
GTF2IBgeesural nerve1.00infobox
GTF2IBgeeventricular zone1.00infobox
GTF2IBgeeright uterine tube1.00infobox
GTF2IBgeeright adrenal cortex1.00infobox
GTF2IBgeeright lobe of thyroid gland1.00infobox
GTF2IBgeeleft lobe of thyroid gland1.00infobox
GTF2IBgeeright ovary1.00infobox
GTF2IBgeebody of pancreas1.00infobox
GTF2IBgeeutricle1.00infobox
GTF2IBgeespermatocyte1.00infobox
GTF2IBgeemolar1.00infobox
GTF2IBgeeprimitive streak1.00infobox
GTF2IBgeevestibular sensory epithelium1.00infobox
GTF2IBgeesuperior surface of tongue1.00infobox
GTF2IBgeemedullary collecting duct1.00infobox
GTF2IBgeerenal corpuscle1.00infobox
GTF2IBgeeretinal pigment epithelium1.00infobox
GTF2IBgeeciliary body1.00infobox
GTF2IBioGPSn/a1.00infobox
GTF2IChr.Chromosome 7 (human)1.00infobox
GTF2IChr.Chromosome 5 (mouse)1.00infobox
GTF2IDatabasesNCBI: entry; OMA: entry1.00infobox
GTF2IEnd74,760,692 bp1.00infobox
GTF2IEnd134,314,760 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GTF2I bring nearby vocabulary together. In this analysis, examples include Human, Protein and Transcription. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GTF2I
    • Human
    • Protein
    • Transcription
    • Chromosome
    • Function
    • Kinase
    • Search
    • Single
    • Tfii-i
    • Location
    • Bp
    • Chr
  • gtf2i
    • Human
    • Protein
    • Transcription
    • Chromosome
    • Function
    • Kinase
    • Search
    • Single
    • Tfii-i
    • Location
    • Bp
    • Chr
  • gene
    • Chromosome
    • Gtf2i
    • Human
    • Location
    • Transcription
    • Bp
    • Chr
    • End
    • Function
    • G2
    • General
    • Humans
  • serum response factor
    • Transcription
    • Gene
    • Function
    • General
    • Gtf2i
    • Kinase
    • Search
    • Tfii-i
    • Human
    • Location
    • Protein
    • Bp
  • usf1 (human gene)
    • Chromosome
    • Gtf2i
    • Location
    • Human
    • Band
    • Transcription
    • Bp
    • Chr
    • End
    • G2
    • Kinase
    • Mouse
  • function
    • Search
    • Tfii-i
    • Location
    • Transcription
    • External
    • Interactions
    • Links
    • Reading
    • References
    • Signal
    • Transduction
    • Bp
  • protein
    • Transcription
    • Gtf2i
    • Signal
    • Transduction
    • Human
    • End
    • Function
    • G2
    • Humans
    • Kinase
    • Mouse
    • Search
  • 7q11.23 duplication syndrome
    • 7q11
    • Syndrome
    • Chromosome
    • End
    • G2
    • Gene
    • Mouse
    • Location
    • Band
    • Bp
    • Chr
    • Human

Connections between topic areas Semantic bridges

For GTF2I, one of the stronger structural bridges in this analysis connects GTF2I with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GTF2IInteractions · splits 7 ⟂ 10
GTF2IOverview · splits 14 ⟂ 3
GTF2IFunction · splits 14 ⟂ 3

Map overview Semantic statistics

GTF2I

Nodes17
Edges16
Triples106
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around GTF2I to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GTF2I · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.