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P300/CBP-associated factor (PCAF), also known as K(lysine) acetyltransferase 2B (KAT2B), is a human gene and transcriptional coactivator associated with p53.
The analysis highlights Interactions, Function and Structure as prominent areas in the source structure around PCAF.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PCAF shows recurring relationship patterns in the source. For example, PCAF → A band, acetyltransferase activity, actomyosin, acyltransferase activity, cell cycle, cellular response to insulin stimulus, centrosome, chromatin binding, chromatin remodeling, cyclin-dependent protein serine/threonine kinase inhibitor activity, cytoplasm, cytoskeleton, development of the heart, diamine N-acetyltransferase activity, epigenetic maintenance of chromatin in transcription-competent conformation, histone acetylation, histone acetyltransferase activity, histone acetyltransferase complex, histone deacetylase binding, histone H3 acetylation Another extracted example is PCAF → Achilles tendon, amniotic fluid, ankle, buccal mucosa cell, corpus callosum, Epithelium of choroid plexus, extensor digitorum longus muscle, external globus pallidus, gastrula, iris, nasal epithelium, olfactory epithelium, pars compacta, pars reticulata, retinal pigment epithelium, seminal vesicula, Skeletal muscle tissue of rectus abdominis, subthalamic nucleus, trabecular bone, vestibular membrane of cochlear duct. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
acetyltransferase activity human bp gene p300 chr band protein chromosome also kat2b location lysine external transcription acetylation p53 regulation cbp
TTTA extracted 161 structured relationships around PCAF. Examples in this analysis include PCAF → 2.3.1.48 → ↗ and PCAF → Aliases → KAT2B, CAF, P/CAF, PCAF, lysine acetyltransferase 2B. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PCAF | 2.3.1.48 | ↗ | 1.00 | infobox |
| PCAF | 2.3.1.57 | ↗ | 1.00 | infobox |
| PCAF | Aliases | KAT2B, CAF, P/CAF, PCAF, lysine acetyltransferase 2B | 1.00 | infobox |
| PCAF | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CM0, 1JM4, 1N72, 1WUG, 1WUM, 1ZS5, 2RNW, 2RNX, 3GG3, 4NSQ, 5FE2, 5FE4, 5FDZ, 5FE8, 5FE5, 5FE1, 5FE7, 5FE9,… | 1.00 | infobox |
| PCAF | Band | 3p24.3 | 1.00 | infobox |
| PCAF | Band | 17 C|17 27.86 cM | 1.00 | infobox |
| PCAF | Bgee | external globus pallidus | 1.00 | infobox |
| PCAF | Bgee | trabecular bone | 1.00 | infobox |
| PCAF | Bgee | buccal mucosa cell | 1.00 | infobox |
| PCAF | Bgee | corpus callosum | 1.00 | infobox |
| PCAF | Bgee | Achilles tendon | 1.00 | infobox |
| PCAF | Bgee | subthalamic nucleus | 1.00 | infobox |
| PCAF | Bgee | pars reticulata | 1.00 | infobox |
| PCAF | Bgee | amniotic fluid | 1.00 | infobox |
| PCAF | Bgee | Skeletal muscle tissue of rectus abdominis | 1.00 | infobox |
| PCAF | Bgee | pars compacta | 1.00 | infobox |
| PCAF | Bgee | retinal pigment epithelium | 1.00 | infobox |
| PCAF | Bgee | nasal epithelium | 1.00 | infobox |
| PCAF | Bgee | olfactory epithelium | 1.00 | infobox |
| PCAF | Bgee | Epithelium of choroid plexus | 1.00 | infobox |
| PCAF | Bgee | iris | 1.00 | infobox |
| PCAF | Bgee | seminal vesicula | 1.00 | infobox |
| PCAF | Bgee | vestibular membrane of cochlear duct | 1.00 | infobox |
| PCAF | Bgee | gastrula | 1.00 | infobox |
| PCAF | Bgee | extensor digitorum longus muscle | 1.00 | infobox |
| PCAF | Bgee | ankle | 1.00 | infobox |
| PCAF | BioGPS | More reference expression data | 1.00 | infobox |
| PCAF | Chr. | Chromosome 3 (human) | 1.00 | infobox |
| PCAF | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| PCAF | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
The concept neighborhoods around PCAF bring nearby vocabulary together. In this analysis, examples include Activity, Protein and Target. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PCAF, one of the stronger structural bridges in this analysis connects PCAF with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PCAF to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PCAF · EN edition · Analysis: TopicsToTalkAbout