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SAE1: Measurement & Standards

SUMO-activating enzyme subunit 1 is a protein that in humans is encoded by the SAE1 gene.

Language: English [EN]
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SAE1 topic overview

The analysis highlights Measurement and Standards as prominent areas in the source structure around SAE1.

Related topics
4
Source areas
2
Connected nodes
6
Extracted relationships
82
Concept neighborhoods
5
Bridge connections
6

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SAE1, AOS1, HSPC140, SUA1, UBLE1A, SUMO1 activating enzyme subunit 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Y8Q, 1Y8R, 3KYC, 3KYD
Band
19q13.32 · 7 A2|7 8.88 cM
Bgee
ventricular zone · ganglionic eminence · muscle layer of sigmoid colon · stromal cell of endometrium · left testis
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 7 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SAE1 connects Entity context

The extracted context around SAE1 shows recurring relationship patterns in the source. For example, SAE1 → abdominal wall, epiblast, ganglionic eminence, gonad, left testis, mandibular prominence, maxillary prominence, muscle layer of sigmoid colon, neural tube, oocyte, prefrontal cortex, primitive streak, right testis, smooth muscle tissue, somite, stromal cell of endometrium, tail of embryo, ventricular zone, yolk sac Another extracted example is SAE1 → ATP-dependent protein binding, cytoplasm, enzyme activator activity, ligase activity, nucleoplasm, nucleus, positive regulation of catalytic activity, positive regulation of protein targeting to mitochondrion, protein binding, protein C-terminus binding, protein heterodimerization activity, protein sumoylation, protein ubiquitination, small protein activating enzyme binding, SUMO activating enzyme activity, SUMO activating enzyme complex, ubiquitin activating enzyme activity, ubiquitin-like modifier activating enzyme activity. Use these groups to spot repeated connection types before inspecting the individual relationships.

SAE1

Top relations

Bgee · 19
SAE1 → abdominal wall, epiblast, ganglionic eminence, gonad, left testis, mandibular prominence, maxillary prominence, muscle layer of sigmoid colon, neural tube, oocyte, prefrontal cortex, primitive streak, right testis, smooth muscle tissue, somite, stromal cell of endometrium, tail of embryo, ventricular zone, yolk sac
RNA expression pattern · 19
SAE1 → abdominal wall, epiblast, ganglionic eminence, gonad, left testis, mandibular prominence, maxillary prominence, muscle layer of sigmoid colon, neural tube, oocyte, prefrontal cortex, primitive streak, right testis, smooth muscle tissue, somite, stromal cell of endometrium, tail of embryo, ventricular zone, yolk sac
Gene ontology · 18
SAE1 → ATP-dependent protein binding, cytoplasm, enzyme activator activity, ligase activity, nucleoplasm, nucleus, positive regulation of catalytic activity, positive regulation of protein targeting to mitochondrion, protein binding, protein C-terminus binding, protein heterodimerization activity, protein sumoylation, protein ubiquitination, small protein activating enzyme binding, SUMO activating enzyme activity, SUMO activating enzyme complex, ubiquitin activating enzyme activity, ubiquitin-like modifier activating enzyme activity
Band · 2
SAE1 → 19q13.32, 7 A2|7 8.88 cM
Chr. · 2
SAE1 → Chromosome 19 (human), Chromosome 7 (mouse)
End · 2
SAE1 → 16,121,731 bp, 47,210,636 bp
related to Interactions · 2
SAE1 → SAE2, UBA2
Aliases · 1
SAE1 → SAE1, AOS1, HSPC140, SUA1, UBLE1A, SUMO1 activating enzyme subunit 1
Available structures · 1
SAE1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Y8Q, 1Y8R, 3KYC, 3KYD
BioGPS · 1
SAE1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene human bp chr band chromosome 19 location enzyme protein mouse ucsc subunit external activating search 210 636 end 47

SAE1 relationships Subject–Predicate–Object triples

TTTA extracted 82 structured relationships around SAE1. Examples in this analysis include SAE1 → Aliases → SAE1, AOS1, HSPC140, SUA1, UBLE1A, SUMO1 activating enzyme subunit 1 and SAE1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Y8Q, 1Y8R, 3KYC, 3KYD. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SAE1AliasesSAE1, AOS1, HSPC140, SUA1, UBLE1A, SUMO1 activating enzyme subunit 11.00infobox
SAE1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Y8Q, 1Y8R, 3KYC, 3KYD1.00infobox
SAE1Band19q13.321.00infobox
SAE1Band7 A2|7 8.88 cM1.00infobox
SAE1Bgeeventricular zone1.00infobox
SAE1Bgeeganglionic eminence1.00infobox
SAE1Bgeemuscle layer of sigmoid colon1.00infobox
SAE1Bgeestromal cell of endometrium1.00infobox
SAE1Bgeeleft testis1.00infobox
SAE1Bgeeright testis1.00infobox
SAE1Bgeegonad1.00infobox
SAE1Bgeeoocyte1.00infobox
SAE1Bgeeprefrontal cortex1.00infobox
SAE1Bgeesmooth muscle tissue1.00infobox
SAE1Bgeeepiblast1.00infobox
SAE1Bgeeprimitive streak1.00infobox
SAE1Bgeesomite1.00infobox
SAE1Bgeeabdominal wall1.00infobox
SAE1Bgeemandibular prominence1.00infobox
SAE1Bgeeneural tube1.00infobox
SAE1Bgeemaxillary prominence1.00infobox
SAE1Bgeeyolk sac1.00infobox
SAE1Bgeetail of embryo1.00infobox
SAE1BioGPSMore reference expression data1.00infobox
SAE1Chr.Chromosome 19 (human)1.00infobox
SAE1Chr.Chromosome 7 (mouse)1.00infobox
SAE1DatabasesNCBI: entry; OMA: entry1.00infobox
SAE1End47,210,636 bp1.00infobox
SAE1End16,121,731 bp1.00infobox
SAE1EnsemblENSG000001422301.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SAE1 bring nearby vocabulary together. In this analysis, examples include Gene, Ucsc and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Sae1
    • Human
    • Location
    • Ucsc
    • Chromosome
    • Bp
    • Chr
    • A2
    • Activating
    • Browser
    • End
    • Genome
  • SAE1
    • Gene
    • Ucsc
    • Human
    • Location
    • Activating
    • Browser
    • Genome
    • Search
    • Subunit
    • Chromosome
    • Bp
    • Chr
  • sae1
    • Gene
    • Ucsc
    • Human
    • Location
    • Activating
    • Browser
    • Genome
    • Search
    • Subunit
    • Chromosome
    • Bp
    • Chr
  • protein
    • Encoded
    • Humans
    • Sumo-activating
    • Sae1
    • A2
    • Activating
    • End
    • Gene
    • Mouse
    • Search
    • Subunit
    • Ucsc
  • interactions
    • External
    • Links
    • Reading
    • References
    • Activating
    • Search
    • Subunit
    • Chromosome
    • Location
    • Bp
    • Chr
    • Sae1

Connections between topic areas Semantic bridges

For SAE1, one of the stronger structural bridges in this analysis connects SAE1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SAE1Overview · splits 4 ⟂ 3
SAE1Interactions · splits 4 ⟂ 3

Map overview Semantic statistics

SAE1

Nodes7
Edges6
Triples82
Avg. degree1.71
Density0.285714
Components1

Source & methodology

TTTA analyzes the structure around SAE1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SAE1 · EN edition · Analysis: TopicsToTalkAbout

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