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Methylphenidate

Methylphenidate, sold under the brand names Ritalin and Concerta, among others, is a central nervous system (CNS) stimulant used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It may be taken by mouth or applied to the skin, and different formulations have varying durations of effect. For ADHD, the effectiveness of…

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3D model (JSmol)
Interactive image
Addiction liability
Moderate
AHFS/Drugs.com
Monograph
ATC code
N06BA04 (WHO)
Bioavailability
Oral: ~30% (range: 11–52%)
Boiling point
136 °C (277 °F)

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Overview

Uses

Contraindications

Adverse effects

Interactions

Pharmacology

Chemistry

History

Society and culture

Etymology

Research

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Map overview Semantic statistics

Methylphenidate

Nodes299
Edges298
Triples212
Avg. degree1.99
Density0.006689
Components1

How this topic connects Entity context

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Methylphenidate

Top relations

related to Names · 28
Methylphenidate → Adaphen, AddWize, Artige, Attenta, Belgium, Brand, Cognil, Concerta, Equasym, Foquest, Inspiral, Konsenidat, Leandro Panizzon, Medikinet, Medikinet XL, Methmild, Methylin, Methylphenidate TAD, Penid, Phenida
related to history · 20
Methylphenidate → ADHD, American, Beginning, Benzedrine, Centedrin, Charles Bradley, CIBA, He, It, Leandro Panizzon, Marguerite, Novartis, Originally, Production, Rita, Ritalin, Subsequent, Swiss, The, United States
related to Chemistry · 15
Methylphenidate → Cocaine, DAT, Despite, Four, However, MPH, NDRI, NET, One, SERTs, Since, SNDRI, The, TMP, When
Legal status · 10
Methylphenidate → AU: S8 (Controlled drug), BR: Class A3 (Psychoactive drugs), CA: Schedule III, DE: Anlage III (Special prescription form required), EU: Rx-only, NZ: Class B2 -authority required, SE: Förteckning II, UK: Class B, UN: Psychotropic Schedule II, US: Schedule II
has effect · 9
Methylphenidate → ADHD, Cardiac, Gastrointestinal, In, Nervous, Ophthalmologic, Results, Smokers, The
related to Pharmacodynamics · 8
Methylphenidate → ADHD, As, By, It, NDRI, Psychostimulants, Therefore, When
related to Controversy · 7
Methylphenidate → ADHD, Among, For, Iceland, People, Ritalin, The
related to Etymology · 7
Methylphenidate → Leandro Panizzon, Marguerite, Methyl-2-phenyl-2, Panizzon, Rita, Ritalin, The
related to Pharmacokinetics · 7
Methylphenidate → Concerta, ER, IR, L/kg, Ritalin, Ritalin LA, The
related to Enhancing performance · 6
Methylphenidate → ADHD, Based, D1, However, Methylphenidate's, Stimulants

Important terminology Word statistics

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Important terminology

adhd dopamine effects may use treatment drug norepinephrine used amphetamine administration hours ritalin children doses reuptake adverse disorder studies increase

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Methylphenidate3D model (JSmol)Interactive image1.00infobox
MethylphenidateAddiction liabilityModerate1.00infobox
MethylphenidateAHFS/Drugs.comMonograph1.00infobox
MethylphenidateATC codeN06BA04 (WHO)1.00infobox
MethylphenidateBioavailabilityOral: ~30% (range: 11–52%)1.00infobox
MethylphenidateBoiling point136 °C (277 °F)1.00infobox
MethylphenidateCAS Number20748-11-2 Y1.00infobox
MethylphenidateChEBICHEBI:6887 Y1.00infobox
MethylphenidateChEMBLChEMBL796 Y1.00infobox
MethylphenidateChemSpider4015 Y1.00infobox
MethylphenidateCompTox Dashboard (EPA)DTXSID50232991.00infobox
MethylphenidateDependence liabilityPhysical: None Psychological: Moderate1.00infobox
MethylphenidateDrug classStimulant; Norepinephrine–dopamine reuptake inhibitor (NDRI)1.00infobox
MethylphenidateDrugBankDB00422 Y1.00infobox
MethylphenidateDuration of actionIR dosing: 3–4 hours1.00infobox
MethylphenidateDuration of actionER dosing: 8–12 hours1.00infobox
MethylphenidateECHA InfoCard100.003.6621.00infobox
MethylphenidateElimination half-life2–3 hours1.00infobox
MethylphenidateExcretionUrine (90%)1.00infobox
MethylphenidateFormulaC14H19NO21.00infobox
MethylphenidateIUPHAR/BPS72361.00infobox
MethylphenidateKEGGD04999 Y1.00infobox
MethylphenidateLegal statusAU: S8 (Controlled drug)1.00infobox
MethylphenidateLegal statusBR: Class A3 (Psychoactive drugs)1.00infobox
MethylphenidateLegal statusCA: Schedule III1.00infobox
MethylphenidateLegal statusDE: Anlage III (Special prescription form required)1.00infobox
MethylphenidateLegal statusNZ: Class B2 -authority required1.00infobox
MethylphenidateLegal statusUK: Class B1.00infobox
MethylphenidateLegal statusUS: Schedule II1.00infobox
MethylphenidateLegal statusUN: Psychotropic Schedule II1.00infobox

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