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Orphenadrine

Orphenadrine is an anticholinergic drug of the ethanolamine antihistamine class; it is closely related to diphenhydramine. It is a muscle relaxant that is used to treat muscle pain and to help with motor control in Parkinson's disease, but has largely been superseded by newer drugs.[citation needed] It is considered a dirty drug due to its multiple…

History & Applications

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
M03BC01 (WHO) N04AB02 (WHO)
Bioavailability
90%
CAS Number
83-98-7 Y
ChEBI
CHEBI:7789 Y

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Overview

Medical uses

Side effects

Pharmacology

History

Formulation

Chemistry

Advanced semantic analysis

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Map overview Semantic statistics

Orphenadrine

Nodes54
Edges53
Triples66
Avg. degree1.96
Density0.037037
Components1

How this topic connects Entity context

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Orphenadrine

Top relations

related to history · 12
Orphenadrine → Cincinnati, Director, Fred Huber, George Rieveschl, In, Parke-Davis, Parkinson's, Prior, Research, Rieveschl, University, While
related to Pharmacology · 8
Orphenadrine → H1, Ki, Nav1, NDRI, NMDA, Nonselective, These, Various
Legal status · 5
Orphenadrine → AU: S4 (Prescription only), CA: OTC, NZ: Prescription only, UK: POM (Prescription only), US: ℞-only
has effect · 4
Orphenadrine → Common, Its, Parkinson's, Stimulation
related to Formulation · 2
Orphenadrine → February, US
3D model (JSmol) · 1
Orphenadrine → Interactive image
AHFS/Drugs.com · 1
Orphenadrine → Monograph
ATC code · 1
Orphenadrine → M03BC01 (WHO) N04AB02 (WHO)
Bioavailability · 1
Orphenadrine → 90%
CAS Number · 1
Orphenadrine → 83-98-7 Y

Important terminology Word statistics

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Important terminology

drugs pain drug anticholinergic diphenhydramine use muscle parkinson's antihistamines used effects one motor side antihistamine common class related relaxant treat

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Orphenadrine3D model (JSmol)Interactive image1.00infobox
OrphenadrineAHFS/Drugs.comMonograph1.00infobox
OrphenadrineATC codeM03BC01 (WHO) N04AB02 (WHO)1.00infobox
OrphenadrineBioavailability90%1.00infobox
OrphenadrineCAS Number83-98-7 Y1.00infobox
OrphenadrineChEBICHEBI:7789 Y1.00infobox
OrphenadrineChEMBLChEMBL900 Y1.00infobox
OrphenadrineChemSpider4440 Y1.00infobox
OrphenadrineCompTox Dashboard (EPA)DTXSID30233961.00infobox
OrphenadrineDrugBankDB01173 Y1.00infobox
OrphenadrineECHA InfoCard100.001.3721.00infobox
OrphenadrineElimination half-life13–20 hours1.00infobox
OrphenadrineExcretionRenal and biliary1.00infobox
OrphenadrineFormulaC18H23NO1.00infobox
OrphenadrineIUPHAR/BPS72511.00infobox
OrphenadrineKEGGD08305 Y1.00infobox
OrphenadrineLegal statusAU: S4 (Prescription only)1.00infobox
OrphenadrineLegal statusCA: OTC1.00infobox
OrphenadrineLegal statusNZ: Prescription only1.00infobox
OrphenadrineLegal statusUK: POM (Prescription only)1.00infobox
OrphenadrineLegal statusUS: ℞-only1.00infobox
OrphenadrineMedlinePlusa6821621.00infobox
OrphenadrineMetabolismHepatic demethylation1.00infobox
OrphenadrineMolar mass269.388 g·mol−11.00infobox
OrphenadrinePregnancy categoryAU: B21.00infobox
OrphenadrineProtein binding95%1.00infobox
OrphenadrinePubChem CID46011.00infobox
OrphenadrineRoutes of administrationOral, intravenous, intramuscular1.00infobox
OrphenadrineUNIIAL805O9OG91.00infobox
Orphenadrineis aanticholinergic drug of the ethanolamine antihistamine class0.90text

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