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Tyramine: Occurrence, Biological activity & Overview

Tyramine (/ˈtaɪrəmiːn/ TY-rə-meen) (also spelled tyramin), also known under several other names, is a naturally occurring trace amine derived from the amino acid tyrosine. Tyramine acts as a catecholamine releasing agent. Notably, it is unable to cross the blood-brain barrier, resulting in only non-psychoactive peripheral sympathomimetic effects…

Language: English [EN]
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Tyramine topic overview

The analysis highlights Occurrence, Biological activity and Overview as prominent areas in the source structure around Tyramine.

Related topics
96
Source areas
4
Connected nodes
100
Extracted relationships
60
Concept neighborhoods
29
Bridge connections
100

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Biological activity · 40 topics
Occurrence · 27 topics
Overview · 24 topics
Biosynthesis · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
none
Boiling point
206 °C (403 °F) at 25 mmHg; 166 °C at 2 mmHg
CAS Number
51-67-2 Y
ChEBI
CHEBI:15760 Y
ChEMBL
ChEMBL11608 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Occurrence

Biological activity

Biosynthesis

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Tyramine connects Entity context

The extracted context around Tyramine shows recurring relationship patterns in the source. For example, Tyramine → Agrotis, Anopheles, Apis, Bombyx, Caenorhabditis, Chilo, Drosophila, Heliothis, In, Locusta, Mamestra, Papilio, Periplaneta, Phormia, Rhipicephalus Another extracted example is Tyramine → Additionally, CYP2D6, DBH, Evidence, FMO3, Human, If, MAO-A, MAOIs, NDRA, PNMT, TAAR1, The TAAR1. Use these groups to spot repeated connection types before inspecting the individual relationships.

Tyramine

Top relations

related to In animals · 15
Tyramine → Agrotis, Anopheles, Apis, Bombyx, Caenorhabditis, Chilo, Drosophila, Heliothis, In, Locusta, Mamestra, Papilio, Periplaneta, Phormia, Rhipicephalus
related to Biological activity · 13
Tyramine → Additionally, CYP2D6, DBH, Evidence, FMO3, Human, If, MAO-A, MAOIs, NDRA, PNMT, TAAR1, The TAAR1
related to Biosynthesis · 5
Tyramine → Biochemically, N-dimethyltyramine, N-methyltyramine, N-trimethyltyramine, TyramineN-MethyltyramineN
related to Occurrence · 3
Tyramine → Foods, In, Specific
3D model (JSmol) · 1
Tyramine → Interactive image
ATC code · 1
Tyramine → none
Boiling point · 1
Tyramine → 206 °C (403 °F) at 25 mmHg; 166 °C at 2 mmHg
CAS Number · 1
Tyramine → 51-67-2 Y
ChEBI · 1
Tyramine → CHEBI:15760 Y
ChEMBL · 1
Tyramine → ChEMBL11608 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

monoamine norepinephrine foods oxidase tyrosine dopamine including also inhibitors ingestion octopamine found sympathomimetic activity response migraine crisis trace releasing agent

Tyramine relationships Subject–Predicate–Object triples

TTTA extracted 60 structured relationships around Tyramine. Examples in this analysis include Tyramine → 3D model (JSmol) → Interactive image and Tyramine → ATC code → none. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Tyramine3D model (JSmol)Interactive image1.00infobox
TyramineATC codenone1.00infobox
TyramineBoiling point206 °C (403 °F) at 25 mmHg; 166 °C at 2 mmHg1.00infobox
TyramineCAS Number51-67-2 Y1.00infobox
TyramineChEBICHEBI:15760 Y1.00infobox
TyramineChEMBLChEMBL11608 Y1.00infobox
TyramineChemSpider5408 Y1.00infobox
TyramineCompTox Dashboard (EPA)DTXSID20438741.00infobox
TyramineDensity1.103 g/cm3 predicted1.00infobox
TyramineDrug classSympathomimetic; Trace amine-associated receptor 1 agonist; Norepinephrine-dopamine releasing agent; Monoaminergic activity enhancer1.00infobox
TyramineECHA InfoCard100.000.1061.00infobox
TyramineFormulaC8H11NO1.00infobox
TyramineIUPHAR/BPS21501.00infobox
TyramineKEGGC00483 Y1.00infobox
TyramineMelting point164.5 °C (328.1 °F)1.00infobox
TyramineMetabolismCYP2D6, flavin-containing monooxygenase 3, monoamine oxidase A, monoamine oxidase B, phenylethanolamine N-methyltransferase, dopamine β-hydroxylase, others1.00infobox
TyramineMetabolites4-Hydroxyphenylacetaldehyde, dopamine, N-methyltyramine, octopamine1.00infobox
TyramineMolar mass137.182 g·mol−11.00infobox
TyramineOther namesTyramin; 4-Hydroxyphenethylamine; para-Tyramine; p-Tyramine; 4-Tyramine; Mydrial; Uteramin1.00infobox
TyraminePronunciation/ˈtaɪrəmiːn/ TY-rə-meen1.00infobox
TyraminePubChem CID56101.00infobox
TyramineUNIIX8ZC7V0OX31.00infobox
Tyramineis afull agonist of the TAAR1 in rodents and humans.Tyramine is physiologically metabolized by monoamine oxidases0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Tyramine bring nearby vocabulary together. In this analysis, examples include Norepinephrine, Foods and Monoamine. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Tyramine
    • Norepinephrine
    • Foods
    • Monoamine
    • High
    • Octopamine
    • Dopamine
    • Migraine
    • Response
    • Tyrosine
    • Including
    • Oxidase
    • Adrenergic
  • tyramine
    • Norepinephrine
    • Foods
    • Monoamine
    • High
    • Octopamine
    • Dopamine
    • Migraine
    • Response
    • Tyrosine
    • Including
    • Oxidase
    • Adrenergic
  • monoamine oxidase inhibitors
    • Oxidase
    • Maois
    • Inhibitors
    • Monoamine
    • Response
    • Dopamine
    • Found
    • Ty-rə-meen
    • Tyramine
    • Blood
    • Cause
    • High
  • norepinephrine and dopamine releasing agent
    • Agent
    • Releasing
    • Vesicles
    • Sympathomimetic
    • Pressor
    • Dopamine
    • Norepinephrine
    • Response
    • Animals
    • Ty-rə-meen
    • Blood
    • Octopamine
  • monoamine oxidases
    • Oxidase
    • Inhibitors
    • Maois
    • Dopamine
    • Found
    • Tyramine
    • Animals
    • Ty-rə-meen
    • Activity
    • N-methyltyramine
    • Releasing
    • Sympathomimetic
  • monoamine neurotransmitters
    • Oxidase
    • Inhibitors
    • Maois
    • Dopamine
    • Found
    • Tyramine
    • Animals
    • Ty-rə-meen
    • Activity
    • N-methyltyramine
    • Releasing
    • Sympathomimetic
  • adrenergic crisis
    • Hypertensive
    • Ingestion
    • Maois
    • Foods
    • Migraine
    • Inhibitors
    • Oxidase
    • Effects
    • Monoamine
    • Adrenergic
    • Crisis
    • Octopamine
  • synaptic vesicles
    • Pressor
    • Norepinephrine
    • Response
    • Octopamine
    • Adrenergic
    • Hypertensive
    • Maois
    • Blood
    • Cause
    • Crisis
    • High
    • Ingestion

Connections between topic areas Semantic bridges

For Tyramine, one of the stronger structural bridges in this analysis connects Tyramine with Biological activity. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TyramineBiological activity · splits 60 ⟂ 41
TyramineOccurrence · splits 73 ⟂ 28
TyramineOverview · splits 76 ⟂ 25
TyramineBiosynthesis · splits 95 ⟂ 6

Map overview Semantic statistics

Tyramine

Nodes101
Edges100
Triples60
Avg. degree1.98
Density0.019802
Components1

Source & methodology

TTTA analyzes the structure around Tyramine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Occurrence, Biological activity & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Tyramine · EN edition · Analysis: TopicsToTalkAbout

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