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Second-generation antidepressant

The second-generation antidepressants are a class of antidepressants characterized primarily by the era of their introduction, approximately coinciding with the 1970s and 1980s, rather than by their chemical structure or by their pharmacological effect. As a consequence, there is some controversy over which treatments actually belong in this class.

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MeSH
D018687
Use
Depressive disorders

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Second-generation antidepressant

Nodes26
Edges25
Triples7
Avg. degree1.92
Density0.076923
Components1

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Second-generation antidepressant

Top relations

MeSH · 1
Second-generation antidepressant → D018687
Use · 1
Second-generation antidepressant → Depressive disorders

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Important terminology

class antidepressants second-generation sertraline venlafaxine antidepressant serotonin reuptake drug mesh fluoxetine paroxetine mirtazapine nefazodone duloxetine reboxetine medicine characterized primarily era

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Second-generation antidepressantMeSHD0186871.00infobox
Second-generation antidepressantUseDepressive disorders1.00infobox
mirtazapineinstance ofas well as some non-SSRI antidepressants0.80text
nefazodoneinstance ofas well as some non-SSRI antidepressants0.80text
venlafaxineinstance ofas well as some non-SSRI antidepressants0.80text
duloxetineinstance ofas well as some non-SSRI antidepressants0.80text
reboxetineinstance ofas well as some non-SSRI antidepressants0.80text

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