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Triggering receptor expressed on myeloid cells 2 (TREM2) is a protein that in humans is encoded by the TREM2 gene. TREM2 is expressed on macrophages, immature monocyte-derived dendritic cells, osteoclasts, and microglia, which are immune cells in the central nervous system. In the liver, TREM2 is expressed by several cell types, including macrophages…
Function, Clinical significance & Structure
Explore the main themes, entities and connections around TREM2. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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expressed expression cells signaling macrophages liver gene also human protein disease inflammatory microglia dap12 bp tumor associated receptor myeloid cell
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TREM2 | Aliases | TREM2, TREM-2, Trem2a, Trem2b, Trem2c, triggering receptor expressed on myeloid cells 2, PLOSL2 | 1.00 | infobox |
| TREM2 | Band | 6p21.1 | 1.00 | infobox |
| TREM2 | Band | 17|17 C | 1.00 | infobox |
| TREM2 | Bgee | C1 segment | 1.00 | infobox |
| TREM2 | Bgee | amniotic fluid | 1.00 | infobox |
| TREM2 | Bgee | inferior ganglion of vagus nerve | 1.00 | infobox |
| TREM2 | Bgee | substantia nigra | 1.00 | infobox |
| TREM2 | Bgee | optic nerve | 1.00 | infobox |
| TREM2 | Bgee | right coronary artery | 1.00 | infobox |
| TREM2 | Bgee | gallbladder | 1.00 | infobox |
| TREM2 | Bgee | left adrenal gland | 1.00 | infobox |
| TREM2 | Bgee | subthalamic nucleus | 1.00 | infobox |
| TREM2 | Bgee | upper lobe of left lung | 1.00 | infobox |
| TREM2 | Bgee | white adipose tissue | 1.00 | infobox |
| TREM2 | Bgee | striatum of neuraxis | 1.00 | infobox |
| TREM2 | Bgee | hippocampus proper | 1.00 | infobox |
| TREM2 | Bgee | urinary bladder | 1.00 | infobox |
| TREM2 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| TREM2 | Bgee | corpus callosum | 1.00 | infobox |
| TREM2 | Bgee | superior frontal gyrus | 1.00 | infobox |
| TREM2 | Bgee | mesenchyme | 1.00 | infobox |
| TREM2 | Bgee | ovary | 1.00 | infobox |
| TREM2 | Bgee | olfactory bulb | 1.00 | infobox |
| TREM2 | BioGPS | More reference expression data | 1.00 | infobox |
| TREM2 | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| TREM2 | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| TREM2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TREM2 | End | 41,163,186 bp | 1.00 | infobox |
| TREM2 | End | 48,661,175 bp | 1.00 | infobox |
| TREM2 | Ensembl | ENSG00000095970 | 1.00 | infobox |
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