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CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells.
Clinical significance, Structure & Alzheimer's disease
Explore the main themes, entities and connections around CD33. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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bp human chr band sialic chromosome 19 acid gene location gemtuzumab ozogamicin external binding receptor cells mouse siglec-3 siglec3 p67
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CD33 | Aliases | CD33, CD33 molecule, SIGLEC-3, SIGLEC3, p67 | 1.00 | infobox |
| CD33 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5IHB, 5J06, 5J0B, 6D48, 6D49, 6D4A, 6TL8, 7AW6 | 1.00 | infobox |
| CD33 | Band | 19q13.41 | 1.00 | infobox |
| CD33 | Band | 7 B3|7 28.25 cM | 1.00 | infobox |
| CD33 | Bgee | monocyte | 1.00 | infobox |
| CD33 | Bgee | granulocyte | 1.00 | infobox |
| CD33 | Bgee | spleen | 1.00 | infobox |
| CD33 | Bgee | blood | 1.00 | infobox |
| CD33 | Bgee | bone marrow cell | 1.00 | infobox |
| CD33 | Bgee | right coronary artery | 1.00 | infobox |
| CD33 | Bgee | upper lobe of left lung | 1.00 | infobox |
| CD33 | Bgee | right lung | 1.00 | infobox |
| CD33 | Bgee | appendix | 1.00 | infobox |
| CD33 | Bgee | right adrenal cortex | 1.00 | infobox |
| CD33 | Bgee | stroma of bone marrow | 1.00 | infobox |
| CD33 | Bgee | lumbar subsegment of spinal cord | 1.00 | infobox |
| CD33 | Bgee | tibiofemoral joint | 1.00 | infobox |
| CD33 | Bgee | gastrula | 1.00 | infobox |
| CD33 | Bgee | submandibular gland | 1.00 | infobox |
| CD33 | Bgee | calvaria | 1.00 | infobox |
| CD33 | Bgee | superior frontal gyrus | 1.00 | infobox |
| CD33 | BioGPS | n/a | 1.00 | infobox |
| CD33 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| CD33 | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| CD33 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CD33 | End | 51,243,860 bp | 1.00 | infobox |
| CD33 | End | 43,193,852 bp | 1.00 | infobox |
| CD33 | Ensembl | ENSG00000105383 | 1.00 | infobox |
| CD33 | Entrez | 945 | 1.00 | infobox |
| CD33 | External IDs | OMIM: 159590; MGI: 99440; GeneCards: CD33 | 1.00 | infobox |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
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