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Galectin-1: Role in pregnancy, Function & Interactions

Galectin-1 is a protein that in humans is encoded by the LGALS1 gene.

Language: English [EN]
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Galectin-1 topic overview

The analysis highlights Role in pregnancy, Function and Interactions as prominent areas in the source structure around Galectin-1.

Related topics
18
Source areas
5
Connected nodes
23
Extracted relationships
115
Concept neighborhoods
11
Bridge connections
23

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Role in pregnancy · 8 topics
Function · 3 topics
Interactions · 3 topics
Gene and protein · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
LGALS1, GAL1, GBP, galectin 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GZW, 1W6M, 1W6N, 1W6O, 1W6P, 1W6Q, 2KM2, 2ZKN, 3OY8, 3OYW, 3T2T, 3W58, 3W59, 4XBL, 4Q27, 4Q1R, 4Q1P, 4Q2F,…
Band
22q13.1 · 15 E1|15 37.7 cM
Bgee
stromal cell of endometrium · decidua · Descending thoracic aorta · ascending aorta · spinal ganglia
BioGPS
More reference expression data
Chr.
Chromosome 22 (human) · Chromosome 15 (mouse)

Suggested research paths

A focused starting point derived from the topic graph, ranked independently of the source article order.

Start with these areas

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Gene and protein

Function

Role in pregnancy

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Galectin-1 connects Entity context

The extracted context around Galectin-1 shows recurring relationship patterns in the source. For example, Galectin-1 → apoptotic process, carbohydrate binding, cell surface, cellular response to glucose stimulus, cellular response to organic cyclic compound, cytoplasm, cytosol, endoplasmic reticulum lumen, extracellular exosome, extracellular matrix, extracellular region, extracellular space, intracellular anatomical structure, lactose binding, laminin binding, myoblast differentiation, negative regulation of cell-substrate adhesion, negative regulation of neuron projection development, nucleus, plasma cell differentiation Another extracted example is Galectin-1 → ascending aorta, body of uterus, calvaria, condyle, decidua, dermis, Descending thoracic aorta, efferent ductule, endothelial cell of lymphatic vessel, external carotid artery, fossa, internal carotid artery, left coronary artery, myometrium, periodontal fiber, spinal ganglia, stromal cell of endometrium, trigeminal ganglion, vas deferens. Use these groups to spot repeated connection types before inspecting the individual relationships.

Galectin-1

Top relations

Gene ontology · 34
Galectin-1 → apoptotic process, carbohydrate binding, cell surface, cellular response to glucose stimulus, cellular response to organic cyclic compound, cytoplasm, cytosol, endoplasmic reticulum lumen, extracellular exosome, extracellular matrix, extracellular region, extracellular space, intracellular anatomical structure, lactose binding, laminin binding, myoblast differentiation, negative regulation of cell-substrate adhesion, negative regulation of neuron projection development, nucleus, plasma cell differentiation
Bgee · 19
Galectin-1 → ascending aorta, body of uterus, calvaria, condyle, decidua, dermis, Descending thoracic aorta, efferent ductule, endothelial cell of lymphatic vessel, external carotid artery, fossa, internal carotid artery, left coronary artery, myometrium, periodontal fiber, spinal ganglia, stromal cell of endometrium, trigeminal ganglion, vas deferens
RNA expression pattern · 19
Galectin-1 → ascending aorta, body of uterus, calvaria, condyle, decidua, dermis, Descending thoracic aorta, efferent ductule, endothelial cell of lymphatic vessel, external carotid artery, fossa, internal carotid artery, left coronary artery, myometrium, periodontal fiber, spinal ganglia, stromal cell of endometrium, trigeminal ganglion, vas deferens
related to Function · 8
Galectin-1 → CD8, Gal-1, HIV, HIV-1, Hodgkin Lymphoma, It, T-cells, The
related to Gene and protein · 8
Galectin-1 → Dimers, Galectin, Galectins, Having, It, LGALS1, The, This
related to Role in pregnancy · 3
Galectin-1 → Dendritic, HLA-G, It
Band · 2
Galectin-1 → 15 E1|15 37.7 cM, 22q13.1
Chr. · 2
Galectin-1 → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
Galectin-1 → 37,679,802 bp, 78,814,665 bp
Aliases · 1
Galectin-1 → LGALS1, GAL1, GBP, galectin 1

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene lgals1 chr protein human band chromosome 22 galectin location role also mouse expression cell binding carbohydrate function external

Galectin-1 relationships Subject–Predicate–Object triples

TTTA extracted 115 structured relationships around Galectin-1. Examples in this analysis include Galectin-1 → Aliases → LGALS1, GAL1, GBP, galectin 1 and Galectin-1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GZW, 1W6M, 1W6N, 1W6O, 1W6P, 1W6Q, 2KM2, 2ZKN, 3OY8, 3OYW, 3T2T, 3W58, 3W59, 4XBL, 4Q27, 4Q1R, 4Q1P, 4Q2F,…. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Galectin-1AliasesLGALS1, GAL1, GBP, galectin 11.00infobox
Galectin-1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GZW, 1W6M, 1W6N, 1W6O, 1W6P, 1W6Q, 2KM2, 2ZKN, 3OY8, 3OYW, 3T2T, 3W58, 3W59, 4XBL, 4Q27, 4Q1R, 4Q1P, 4Q2F,…1.00infobox
Galectin-1Band22q13.11.00infobox
Galectin-1Band15 E1|15 37.7 cM1.00infobox
Galectin-1Bgeestromal cell of endometrium1.00infobox
Galectin-1Bgeedecidua1.00infobox
Galectin-1BgeeDescending thoracic aorta1.00infobox
Galectin-1Bgeeascending aorta1.00infobox
Galectin-1Bgeespinal ganglia1.00infobox
Galectin-1Bgeeperiodontal fiber1.00infobox
Galectin-1Bgeebody of uterus1.00infobox
Galectin-1Bgeemyometrium1.00infobox
Galectin-1Bgeeleft coronary artery1.00infobox
Galectin-1Bgeetrigeminal ganglion1.00infobox
Galectin-1Bgeeendothelial cell of lymphatic vessel1.00infobox
Galectin-1Bgeedermis1.00infobox
Galectin-1Bgeeefferent ductule1.00infobox
Galectin-1Bgeevas deferens1.00infobox
Galectin-1Bgeeinternal carotid artery1.00infobox
Galectin-1Bgeecalvaria1.00infobox
Galectin-1Bgeecondyle1.00infobox
Galectin-1Bgeeexternal carotid artery1.00infobox
Galectin-1Bgeefossa1.00infobox
Galectin-1BioGPSMore reference expression data1.00infobox
Galectin-1Chr.Chromosome 22 (human)1.00infobox
Galectin-1Chr.Chromosome 15 (mouse)1.00infobox
Galectin-1DatabasesNCBI: entry; OMA: entry1.00infobox
Galectin-1End37,679,802 bp1.00infobox
Galectin-1End78,814,665 bp1.00infobox
Galectin-1EnsemblENSG000001000971.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Galectin-1 bring nearby vocabulary together. In this analysis, examples include Protein, Expressed and Pregnancy. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Location
    • Chromosome
    • Human
    • Lgals1
    • Bp
    • Chr
    • E1
    • End
    • External
    • Function
    • Mouse
    • Protein
  • cell proliferation
    • Cytoplasm
    • Extracellular
    • Nucleus
    • E1
    • End
    • Expressed
    • External
    • Function
    • Mouse
    • Search
    • Signal
    • Stromal
  • gene and protein
    • Location
    • Chromosome
    • Human
    • Lgals1
    • Bp
    • Chr
    • E1
    • End
    • External
    • Function
    • Mouse
    • Protein
  • function
    • External
    • Search
    • Location
    • Chromosome
    • Gene
    • Human
    • Lgals1
    • Bp
    • Chr
    • Protein
    • Cytoplasm
    • E1
  • protein
    • Search
    • Structure
    • Location
    • Human
    • Cytoplasm
    • E1
    • End
    • Expressed
    • Extracellular
    • Interactions
    • Mouse
    • Nucleus
  • Galectin-1
    • Protein
    • Expressed
    • Pregnancy
    • Stromal
    • Also
    • Cell
    • Expression
    • Role
    • Gene
    • Lgals1
  • galectin-1
    • Protein
    • Expressed
    • Pregnancy
    • Stromal
    • Also
    • Cell
    • Expression
    • Role
    • Gene
    • Lgals1
  • interactions
    • Galectins
    • Pregnancy
    • Search
    • Location
    • Role
    • Human
    • Lgals1
    • Protein

Connections between topic areas Semantic bridges

For Galectin-1, one of the stronger structural bridges in this analysis connects Galectin-1 with Role in pregnancy. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Galectin-1 — Role in pregnancy · splits 15 ⟂ 9
Galectin-1 — Function · splits 20 ⟂ 4
Galectin-1 — Interactions · splits 20 ⟂ 4
Galectin-1 — Overview · splits 21 ⟂ 3
Galectin-1 — Gene and protein · splits 21 ⟂ 3

Map overview Semantic statistics

Galectin-1

Nodes24
Edges23
Triples115
Avg. degree1.92
Density0.083333
Components1

Source & methodology

TTTA analyzes the structure around Galectin-1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Role in pregnancy, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Galectin-1 · EN edition · Analysis: TopicsToTalkAbout

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