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Synaptic pruning

Synaptic pruning is the process of synapse elimination or weakening. Though it occurs throughout the lifespan of a mammal, the most active period of synaptic pruning in the development of the nervous system occurs between early childhood and the onset of puberty in many mammals, including humans. Pruning starts near the time of birth and continues into…

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Potential role in schizophrenia

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Synaptic pruning

Nodes81
Edges80
Triples28
Avg. degree1.98
Density0.024691
Components1

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Synaptic pruning

Top relations

related to Potential role in schizophrenia · 6
Synaptic pruning → CNS, Microglia, Microglia-mediated, Microglial, Synaptic, The
related to Pruning in the maturing brain · 6
Synaptic pruning → Axons, Certain, Examples, In, The, This
related to Forgetting problems with learning through pruning · 4
Synaptic pruning → All, It, Since, This
related to Mechanisms · 4
Synaptic pruning → Each, Hormones, In, The
is a · 1
Synaptic pruning → process of synapse elimination or weakening

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Important terminology

pruning synaptic axon connections neurons axons synapses also development brain found retraction synapse schizophrenia system factors seen mechanism terminal observed

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Synaptic pruningis aprocess of synapse elimination or weakening0.90text
schizophreniainstance ofPotential role in schizophreniaSynaptic pruning has been suggested to have a role in the pathology of neurodevelopmental disorders0.80text
as well as in autism spectrum disorder.Microglia have been implicated in synaptic pruninginstance ofPotential role in schizophreniaSynaptic pruning has been suggested to have a role in the pathology of neurodevelopmental disorders0.80text
as they have roles in both the immune response as macrophages as well as in neuronal upkeepinstance ofPotential role in schizophreniaSynaptic pruning has been suggested to have a role in the pathology of neurodevelopmental disorders0.80text
synaptic plasticity in the CNS during fetal developmentinstance ofPotential role in schizophreniaSynaptic pruning has been suggested to have a role in the pathology of neurodevelopmental disorders0.80text
early postnatal developmentinstance ofPotential role in schizophreniaSynaptic pruning has been suggested to have a role in the pathology of neurodevelopmental disorders0.80text
and adolescenceinstance ofPotential role in schizophreniaSynaptic pruning has been suggested to have a role in the pathology of neurodevelopmental disorders0.80text
in which they engulf unneeded or redundant synapses via phagocytosisinstance ofPotential role in schizophreniaSynaptic pruning has been suggested to have a role in the pathology of neurodevelopmental disorders0.80text
Synaptic pruningrelated to Forgetting problems with learning through pruningAll0.60section
Synaptic pruningrelated to Forgetting problems with learning through pruningSince0.60section
Synaptic pruningrelated to Forgetting problems with learning through pruningThis0.60section
Synaptic pruningrelated to Forgetting problems with learning through pruningIt0.60section

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