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Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stressful stimuli like cytokines, free radicals, heavy metals…
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Explore the main themes, entities and connections around NF-κB. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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High-confidence facts extracted from structured source data. Use them as anchors for further research.
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Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
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| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| NF-κB | Domains | InterPro | 1.00 | infobox |
| NF-κB | HGNC | 7794 | 1.00 | infobox |
| NF-κB | Locus | Chr. 4 q24 | 1.00 | infobox |
| NF-κB | NCBI gene | 4790 | 1.00 | infobox |
| NF-κB | OMIM | 164011 | 1.00 | infobox |
| NF-κB | RefSeq | NM_003998 | 1.00 | infobox |
| NF-κB | Search for | Search forStructuresSwiss-modelDomainsInterPro | 1.00 | infobox |
| NF-κB | Structures | Swiss-model | 1.00 | infobox |
| NF-κB | Symbol | NFKB1 | 1.00 | infobox |
| NF-κB | UniProt | P19838 | 1.00 | infobox |
| NF-κB | is a | subject of much active research among pharmaceutical companies as a target for anti-cancer therapy.However | 0.90 | text |
| NF-κB | is a | Fas transcription activator and the alternative NF-κB is a Fas transcription repressor | 0.90 | text |
| NF-κB | is a | central component of the cellular response to damage | 0.90 | text |
| NF-κB | is a | key player in the inflammatory response | 0.90 | text |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.