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CD163

CD163 (Cluster of Differentiation 163) is a protein that in humans is encoded by the CD163 gene. CD163 is the high affinity scavenger receptor for the hemoglobin-haptoglobin complex and in the absence of haptoglobin - with lower affinity - for hemoglobin alone. It also is a marker of cells from the monocyte/macrophage lineage. CD163 functions as innate…

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Clinical significance

Cerebrospinal fluidCirrhosisDiabetesMacrophage activation syndromeGaucher's disease
15 related topics

Differences between mouse and human

ArgSerADAM17
3 related topics

Interactions

InteractCSNK2B
2 related topics

Structure

KDa
1 related topics

Key facts & relationships

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Aliases
CD163, M130, MM130, SCARI1, CD163 molecule
Band
12p13.31 · 6|6 F2
Bgee
right lung · gastric mucosa · lower lobe of lung · right adrenal cortex · spleen
BioGPS
More reference expression data
Chr.
Chromosome 12 (human) · Chromosome 6 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Structure

Clinical significance

Differences between mouse and human

Animal studies

Interactions

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Map overview Semantic statistics

CD163

Nodes39
Edges38
Triples94
Avg. degree1.95
Density0.051282
Components1

How this topic connects Entity context

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CD163

Top relations

Bgee · 20
CD163 → ankle, aortic valve, ascending aorta, gastric mucosa, intercostal muscle, left adrenal cortex, left uterine tube, lower lobe of lung, lumbar spinal ganglion, monocyte, pericardium, right adrenal cortex, right coronary artery, right lung, sciatic nerve, skin of external ear, spleen, stroma of bone marrow, tunica adventitia of aorta, white adipose tissue
RNA expression pattern · 20
CD163 → ankle, aortic valve, ascending aorta, gastric mucosa, intercostal muscle, left adrenal cortex, left uterine tube, lower lobe of lung, lumbar spinal ganglion, monocyte, pericardium, right adrenal cortex, right coronary artery, right lung, sciatic nerve, skin of external ear, spleen, stroma of bone marrow, tunica adventitia of aorta, white adipose tissue
Gene ontology · 12
CD163 → acute-phase response, endocytic vesicle membrane, external side of plasma membrane, extracellular region, inflammatory response, integral component of membrane, integral component of plasma membrane, membrane, plasma membrane, protein binding, receptor-mediated endocytosis, scavenger receptor activity
related to Clinical significance · 8
CD163 → ADAM17, ANCA, CNS, Gaucher's, HIV, Hodgkin, It, The
related to External links · 5
CD163 → Human CD163, Medicine Medical Subject Headings, MeSH, National Library, UCSC Genome Browser
related to Differences between mouse and human · 4
CD163 → ADAM17, Arg-Ser-Ser-Arg, Differences, Human CD163
related to Animal studies · 3
CD163 → Pigs, Porcine Reproductive, Respiratory Syndrome
Band · 2
CD163 → 12p13.31, 6|6 F2
Chr. · 2
CD163 → Chromosome 12 (human), Chromosome 6 (mouse)
End · 2
CD163 → 124,307,486 bp, 7,503,893 bp

Important terminology Word statistics

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Important terminology

human bp gene receptor chr band mouse chromosome 12 location scd163 protein also external scavenger humans monocyte hemoglobin lower macrophage

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CD163AliasesCD163, M130, MM130, SCARI1, CD163 molecule1.00infobox
CD163Band12p13.311.00infobox
CD163Band6|6 F21.00infobox
CD163Bgeeright lung1.00infobox
CD163Bgeegastric mucosa1.00infobox
CD163Bgeelower lobe of lung1.00infobox
CD163Bgeeright adrenal cortex1.00infobox
CD163Bgeespleen1.00infobox
CD163Bgeeleft adrenal cortex1.00infobox
CD163Bgeemonocyte1.00infobox
CD163Bgeeleft uterine tube1.00infobox
CD163Bgeeright coronary artery1.00infobox
CD163Bgeepericardium1.00infobox
CD163Bgeestroma of bone marrow1.00infobox
CD163Bgeelumbar spinal ganglion1.00infobox
CD163Bgeeaortic valve1.00infobox
CD163Bgeeskin of external ear1.00infobox
CD163Bgeeascending aorta1.00infobox
CD163Bgeesciatic nerve1.00infobox
CD163Bgeewhite adipose tissue1.00infobox
CD163Bgeeintercostal muscle1.00infobox
CD163Bgeeankle1.00infobox
CD163Bgeetunica adventitia of aorta1.00infobox
CD163BioGPSMore reference expression data1.00infobox
CD163Chr.Chromosome 12 (human)1.00infobox
CD163Chr.Chromosome 6 (mouse)1.00infobox
CD163DatabasesNCBI: entry; OMA: entry1.00infobox
CD163End7,503,893 bp1.00infobox
CD163End124,307,486 bp1.00infobox
CD163EnsemblENSG000001775751.00infobox

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