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Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded by the human CSF1R gene (known also as c-FMS). CSF1R is a receptor that can be activated by two ligands: colony stimulating factor 1 (CSF-1) and interleukin-34…
The analysis highlights Gene, Protein and Function as prominent areas in the source structure around Colony stimulating factor 1 receptor.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Colony stimulating factor 1 receptor shows recurring relationship patterns in the source. For example, Colony stimulating factor 1 receptor → ATP binding, axon guidance, cell differentiation, cell population proliferation, cell surface, cell-cell junction maintenance, cellular response to cytokine stimulus, cellular response to macrophage colony-stimulating factor stimulus, CSF1-CSF1R complex, cytokine binding, cytokine-mediated signaling pathway, cytoplasm, forebrain neuron differentiation, hematopoietic progenitor cell differentiation, hemopoiesis, immune system process, inflammatory response, innate immune response, integral component of membrane, integral component of plasma membrane Another extracted example is Colony stimulating factor 1 receptor → ankle, appendix, calvaria, gallbladder, gastrula, globus pallidus, granulocyte, inferior ganglion of vagus nerve, internal carotid artery, lymph node, monocyte, motor neuron, placenta, retinal pigment epithelium, right coronary artery, spleen, stroma of bone marrow, substantia nigra, tibiofemoral joint. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
csf1r signaling microglia cells macrophages survival gene csf-1 osteoclasts also bone disease brain human differentiation mouse osteoclast receptor loss-of-function cancer
TTTA extracted 177 structured relationships around Colony stimulating factor 1 receptor. Examples in this analysis include Colony stimulating factor 1 receptor → 2.7.10.1 → ↗ and Colony stimulating factor 1 receptor → Aliases → CSF1R, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R, colony stimulating factor 1 receptor, BANDDOS, HDLS1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Colony stimulating factor 1 receptor | 2.7.10.1 | ↗ | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Aliases | CSF1R, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R, colony stimulating factor 1 receptor, BANDDOS, HDLS1 | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2I0V, 2I0Y, 2I1M, 2OGV, 3BEA, 3DPK, 3KRJ, 3KRL, 3LCD, 3LCO, 4DKD, 4HW7, 4LIQ, 4R7H, 4R7I, 4WRL, 4WRM | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Band | 5q32 | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Band | 18 E1|18 34.41 cM | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | granulocyte | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | monocyte | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | spleen | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | right coronary artery | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | placenta | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | inferior ganglion of vagus nerve | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | retinal pigment epithelium | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | gallbladder | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | appendix | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | lymph node | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | stroma of bone marrow | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | ankle | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | motor neuron | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | tibiofemoral joint | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | internal carotid artery | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | calvaria | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | substantia nigra | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | gastrula | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Bgee | globus pallidus | 1.00 | infobox |
| Colony stimulating factor 1 receptor | BioGPS | More reference expression data | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Chr. | Chromosome 5 (human) | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Chr. | Chromosome 18 (mouse) | 1.00 | infobox |
| Colony stimulating factor 1 receptor | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Colony stimulating factor 1 receptor | End | 150,113,372 bp | 1.00 | infobox |
| Colony stimulating factor 1 receptor | End | 61,265,221 bp | 1.00 | infobox |
The concept neighborhoods around Colony stimulating factor 1 receptor bring nearby vocabulary together. In this analysis, examples include Factor, Stimulating and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Colony stimulating factor 1 receptor, one of the stronger structural bridges in this analysis connects Colony stimulating factor 1 receptor with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Colony stimulating factor 1 receptor to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Gene, Protein & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Colony stimulating factor 1 receptor · EN edition · Analysis: TopicsToTalkAbout