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Telomerase reverse transcriptase (abbreviated to TERT, or hTERT in humans) is a catalytic subunit of the enzyme telomerase, which, together with the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex.
The analysis highlights Measurement, Regulation and Clinical significance as prominent areas in the source structure around Telomerase reverse transcriptase.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Telomerase reverse transcriptase shows recurring relationship patterns in the source. For example, Telomerase reverse transcriptase → beta-catenin-TCF complex assembly, cellular response to hypoxia, chaperone binding, chromosome, cytoplasm, cytosol, DNA binding, DNA biosynthetic process, DNA strand elongation, establishment of protein localization to telomere, identical protein binding, metal ion binding, mitochondrial nucleoid, mitochondrion, mitochondrion organization, negative regulation of apoptotic process, negative regulation of cellular senescence, negative regulation of endothelial cell apoptotic process, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, negative regulation of gene expression Another extracted example is Telomerase reverse transcriptase → cardia, condyle, epithelium of small intestine, external globus pallidus, fossa, genital tubercle, medullary collecting duct, mucosa of pharynx, otic vesicle, Paneth cell, pars reticulata, primary oocyte, pylorus, secondary oocyte, stromal cell of endometrium, superior surface of tongue, tail of embryo, thymus, tongue, vein. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
cells telomerase htert stem gene tert cancer activity telomeres cell telomere human ips rna also expression associated somatic promoter apoptosis
TTTA extracted 176 structured relationships around Telomerase reverse transcriptase. Examples in this analysis include Telomerase reverse transcriptase → 2.7.7.49 → ↗ and Telomerase reverse transcriptase → Aliases → TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT, telomerase reverse transcriptase, HTERT. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Telomerase reverse transcriptase | 2.7.7.49 | ↗ | 1.00 | infobox |
| Telomerase reverse transcriptase | Aliases | TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT, telomerase reverse transcriptase, HTERT | 1.00 | infobox |
| Telomerase reverse transcriptase | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BCK, 4B18, 4MNQ | 1.00 | infobox |
| Telomerase reverse transcriptase | Band | 5p15.33 | 1.00 | infobox |
| Telomerase reverse transcriptase | Band | 13 C1|13 40.12 cM | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | stromal cell of endometrium | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | thymus | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | cardia | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | tongue | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | vein | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | mucosa of pharynx | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | external globus pallidus | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | pylorus | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | superior surface of tongue | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | pars reticulata | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | Paneth cell | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | primary oocyte | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | epithelium of small intestine | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | secondary oocyte | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | medullary collecting duct | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | tail of embryo | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | condyle | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | fossa | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | genital tubercle | 1.00 | infobox |
| Telomerase reverse transcriptase | Bgee | otic vesicle | 1.00 | infobox |
| Telomerase reverse transcriptase | BioGPS | More reference expression data | 1.00 | infobox |
| Telomerase reverse transcriptase | Chr. | Chromosome 5 (human) | 1.00 | infobox |
| Telomerase reverse transcriptase | Chr. | Chromosome 13 (mouse) | 1.00 | infobox |
| Telomerase reverse transcriptase | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Telomerase reverse transcriptase | End | 1,295,068 bp | 1.00 | infobox |
The concept neighborhoods around Telomerase reverse transcriptase bring nearby vocabulary together. In this analysis, examples include Activity, Enzyme and Cells. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Telomerase reverse transcriptase, one of the stronger structural bridges in this analysis connects Telomerase reverse transcriptase with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Telomerase reverse transcriptase to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Regulation & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Telomerase reverse transcriptase · EN edition · Analysis: TopicsToTalkAbout