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TATA box: History, Technology & Regions

In molecular biology, the TATA box (also called the Goldberg–Hogness box) is a sequence of DNA found in the core promoter region of genes in archaea and eukaryotes. The bacterial homolog of the TATA box is called the Pribnow box which has a shorter consensus sequence.

Language: English [EN]
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TATA box topic overview

The analysis highlights History, Technology and Regions as prominent areas in the source structure around TATA box.

Related topics
144
Source areas
8
Connected nodes
152
Extracted relationships
192
Concept neighborhoods
37
Bridge connections
152

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 37 topics
Mutations · 27 topics
Function · 26 topics
Clinical significance · 20 topics
History · 11 topics
Features · 9 topics
Genetic engineering · 8 topics
Structure · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

History

Features

Structure

Function

Mutations

Clinical significance

Genetic engineering

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How TATA box connects Entity context

The extracted context around TATA box shows recurring relationship patterns in the source. For example, TATA box → Also, AT-rich, Box, DPE, Drosophila, Drosophila TATA-less, Even, II, In, In Drosophila, Inr, IRF-1, Most, One, TATA, TATA-binding, TATA-less, TBP, TFIID, The Another extracted example is TATA box → Asn117, Asn27, DNA, Formation, Four, II, Ile152, Leu163, Numerous, Phe148, Phe165, Phe57, Phe74, TATA, TATA-binding, TBP, TFIID, The TATA-box, Thr173, Thr82. Use these groups to spot repeated connection types before inspecting the individual relationships.

TATA box

Top relations

related to history · 23
TATA box → Also, AT-rich, Box, DPE, Drosophila, Drosophila TATA-less, Even, II, In, In Drosophila, Inr, IRF-1, Most, One, TATA, TATA-binding, TATA-less, TBP, TFIID, The
related to Role in transcription initiation · 22
TATA box → Asn117, Asn27, DNA, Formation, Four, II, Ile152, Leu163, Numerous, Phe148, Phe165, Phe57, Phe74, TATA, TATA-binding, TBP, TFIID, The TATA-box, Thr173, Thr82
related to Location · 16
TATA box → II, In, Promoter, RNA, Rpb4/Rbp7, SAGA, SAGA/TATA, TATA, TATA-binding, TBP, TFIID, TFIID/TBP, The, The TATA, When, While
related to Point mutations · 16
TATA box → CATAAAA, For, HeLa, However, KD, Leyden, Point, Savinkova, Some, Studies, TATA, TATAAAA, TATACAA, TBP, Thalassemia, This
related to Cancer therapy · 15
TATA box → Cisplatin, Compounds, DNA, DNA-binding, Example, However, II, In, Pharmaceutical, SN-38, TATA, TATA-binding, TBP, The, This
related to Sequence and prevalence · 15
TATA box → A/G, A/T, DCE, DNA, Generally, Genes, In, Saccharomyces, Similarly, TATA, TATA-box, TATA-containing, TATA-less, The TATA, These
related to Discovery · 13
TATA box → American, Basel, David Hogness, DNA, Drosophila, II, Michael Goldberg, RNA, Switzerland, TATA, The TATA, They, University
related to Analogous sequences · 12
TATA box → CAAT, CAAT TF, CAT, CTFs, GGCCAATCT, In, It, Pribnow, RNA, TATA, The CAAT, The Pribnow
related to TATA box modification · 12
TATA box → Arabidopsis, As, Compared, Earth, Earth's, Evolutionary, In, IRT1, Malus, TATA, TFIID, With
related to Diseases · 10
TATA box → Carriers, Gastric, Longer TATA, Mutations, PG2, TATA, TATA-binding, TBP, The TATA, This

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

box tata transcription tbp sequence promoter dna genes protein gene mutations binding tata-binding upstream also consensus promoters site found eukaryotic

TATA box relationships Subject–Predicate–Object triples

TTTA extracted 192 structured relationships around TATA box. Examples in this analysis include TATA box → is a → binding site of the TATA-binding protein and TATA box → is a → component of the eukaryotic core promoter and generally contains the consensus sequence 5'-TATA. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
TATA boxis abinding site of the TATA-binding protein0.90text
TATA boxis acomponent of the eukaryotic core promoter and generally contains the consensus sequence 5'-TATA0.90text
enhancersinstance ofGene transcription by RNA polymerase II depends on the regulation of the core promoter by long-range regulatory elements0.80text
silencersinstance ofGene transcription by RNA polymerase II depends on the regulation of the core promoter by long-range regulatory elements0.80text
insertionsinstance ofmutations0.80text
deletionsinstance ofmutations0.80text
and point mutations to this consensus sequence can result in phenotypic changesinstance ofmutations0.80text
cell growthinstance ofTATA-containing genes are not involved in essential cellular functions0.80text
DNA replicationinstance ofTATA-containing genes are not involved in essential cellular functions0.80text
transcriptioninstance ofTATA-containing genes are not involved in essential cellular functions0.80text
and translation because of their highly regulated nature.The TATA box is usually located 25-35 base pairs upstream of the transcription start siteinstance ofTATA-containing genes are not involved in essential cellular functions0.80text
HIV-1instance ofThis poses a risk for developing jaundice in newborns.MicroRNAs also play a role in replicating viruses0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around TATA box bring nearby vocabulary together. In this analysis, examples include Tata, Sequence and Tbp. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • TATA box
    • Tata
    • Sequence
    • Tbp
    • Transcription
    • Binding
    • Promoter
    • Region
    • Site
    • Upstream
    • Genes
    • Mutations
    • Found
  • tata box
    • Tata
    • Sequence
    • Tbp
    • Transcription
    • Binding
    • Promoter
    • Region
    • Site
    • Upstream
    • Protein
    • Genes
    • Mutations
  • sequence
    • Consensus
    • Tata
    • Promoter
    • Core
    • Dna
    • Found
    • First
    • Tbp
    • Region
    • Sequences
    • Initiation
    • Mutations
  • core promoter region
    • Promoter
    • Transcription
    • Tata
    • Gene
    • Sequence
    • Genes
    • Bind
    • Eukaryotes
    • Eukaryotic
    • Promoters
    • Found
    • Initiation
  • genes
    • Tata
    • Promoter
    • Transcription
    • Promoters
    • Region
    • Sequence
    • Site
    • Protein
    • Eukaryotes
    • Bind
    • First
    • Polymerase
  • pribnow box
    • Tata
    • Sequence
    • Tbp
    • Transcription
    • Promoter
    • Binding
    • Region
    • Site
    • Upstream
    • Protein
    • Genes
    • Found
  • consensus sequence
    • Consensus
    • Sequence
    • Tata
    • Promoter
    • Core
    • Dna
    • Found
    • First
    • Tbp
    • Region
    • Sequences
    • Initiation
  • downstream promoter element
    • Transcription
    • Tata
    • Sequence
    • Genes
    • Eukaryotes
    • Eukaryotic
    • Promoters
    • Sequences
    • Ii
    • Initiation
    • Upstream
    • Tfiid

Connections between topic areas Semantic bridges

For TATA box, one of the stronger structural bridges in this analysis connects TATA box with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TATA boxOverview · splits 115 ⟂ 38
TATA boxMutations · splits 125 ⟂ 28
TATA boxFunction · splits 126 ⟂ 27
TATA boxClinical significance · splits 132 ⟂ 21
TATA boxHistory · splits 141 ⟂ 12
TATA boxFeatures · splits 143 ⟂ 10
TATA boxGenetic engineering · splits 144 ⟂ 9
TATA boxStructure · splits 146 ⟂ 7

Map overview Semantic statistics

TATA box

Nodes153
Edges152
Triples192
Avg. degree1.99
Density0.013072
Components1

Source & methodology

TTTA analyzes the structure around TATA box to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Technology & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — TATA box · EN edition · Analysis: TopicsToTalkAbout

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