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In molecular biology, the TATA box (also called the Goldberg–Hogness box) is a sequence of DNA found in the core promoter region of genes in archaea and eukaryotes. The bacterial homolog of the TATA box is called the Pribnow box which has a shorter consensus sequence.
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box tata transcription tbp sequence promoter dna genes protein gene mutations binding tata-binding upstream also consensus promoters site found eukaryotic
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TATA box | is a | binding site of the TATA-binding protein | 0.90 | text |
| TATA box | is a | component of the eukaryotic core promoter and generally contains the consensus sequence 5'-TATA | 0.90 | text |
| enhancers | instance of | Gene transcription by RNA polymerase II depends on the regulation of the core promoter by long-range regulatory elements | 0.80 | text |
| silencers | instance of | Gene transcription by RNA polymerase II depends on the regulation of the core promoter by long-range regulatory elements | 0.80 | text |
| insertions | instance of | mutations | 0.80 | text |
| deletions | instance of | mutations | 0.80 | text |
| and point mutations to this consensus sequence can result in phenotypic changes | instance of | mutations | 0.80 | text |
| cell growth | instance of | TATA-containing genes are not involved in essential cellular functions | 0.80 | text |
| DNA replication | instance of | TATA-containing genes are not involved in essential cellular functions | 0.80 | text |
| transcription | instance of | TATA-containing genes are not involved in essential cellular functions | 0.80 | text |
| and translation because of their highly regulated nature.The TATA box is usually located 25-35 base pairs upstream of the transcription start site | instance of | TATA-containing genes are not involved in essential cellular functions | 0.80 | text |
| HIV-1 | instance of | This poses a risk for developing jaundice in newborns.MicroRNAs also play a role in replicating viruses | 0.80 | text |
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