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In molecular biology, the TATA box (also called the Goldberg–Hogness box) is a sequence of DNA found in the core promoter region of genes in archaea and eukaryotes. The bacterial homolog of the TATA box is called the Pribnow box which has a shorter consensus sequence.
The analysis highlights History, Technology and Regions as prominent areas in the source structure around TATA box.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around TATA box shows recurring relationship patterns in the source. For example, TATA box → Asn117, Asn27, DNA, Formation, Four, II, Ile152, Leu163, Phe148, Phe165, Phe57, Phe74, TATA, TATA-binding, TBP, TFIID, The TATA-box, Thr173, Thr82, Three Another extracted example is TATA box → Also, AT-rich, Box, DPE, Drosophila, Drosophila TATA-less, Even, II, In Drosophila, Inr, IRF-1, One, TATA, TATA-binding, TATA-less, TBP, TFIID, The DPE. Use these groups to spot repeated connection types before inspecting the individual relationships.
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box tata transcription tbp sequence promoter dna genes protein gene mutations binding tata-binding upstream also consensus promoters site found eukaryotic
TTTA extracted 159 structured relationships around TATA box. Examples in this analysis include TATA box → is a → binding site of the TATA-binding protein and TATA box → is a → component of the eukaryotic core promoter and generally contains the consensus sequence 5'-TATA. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TATA box | is a | binding site of the TATA-binding protein | 0.90 | text |
| TATA box | is a | component of the eukaryotic core promoter and generally contains the consensus sequence 5'-TATA | 0.90 | text |
| enhancers | instance of | Gene transcription by RNA polymerase II depends on the regulation of the core promoter by long-range regulatory elements | 0.80 | text |
| silencers | instance of | Gene transcription by RNA polymerase II depends on the regulation of the core promoter by long-range regulatory elements | 0.80 | text |
| insertions | instance of | mutations | 0.80 | text |
| deletions | instance of | mutations | 0.80 | text |
| and point mutations to this consensus sequence can result in phenotypic changes | instance of | mutations | 0.80 | text |
| cell growth | instance of | TATA-containing genes are not involved in essential cellular functions | 0.80 | text |
| DNA replication | instance of | TATA-containing genes are not involved in essential cellular functions | 0.80 | text |
| transcription | instance of | TATA-containing genes are not involved in essential cellular functions | 0.80 | text |
| and translation because of their highly regulated nature.The TATA box is usually located 25-35 base pairs upstream of the transcription start site | instance of | TATA-containing genes are not involved in essential cellular functions | 0.80 | text |
| HIV-1 | instance of | This poses a risk for developing jaundice in newborns.MicroRNAs also play a role in replicating viruses | 0.80 | text |
The concept neighborhoods around TATA box bring nearby vocabulary together. In this analysis, examples include Tata, Sequence and Tbp. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For TATA box, one of the stronger structural bridges in this analysis connects TATA box with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around TATA box to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Technology & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — TATA box · EN edition · Analysis: TopicsToTalkAbout
