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Reverse transcriptase

A reverse transcriptase (RT) is an enzyme that uses an RNA molecule as a template to synthesize a complementary DNA molecule, through a process termed reverse transcription. Reverse transcriptases are used by viruses such as HIV and hepatitis B to replicate their genomes, by retrotransposon mobile genetic elements to proliferate within the host genome, an…

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Key facts & relationships

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AlphaFold
IPR000477 · PF00078
Available protein structures:
IPR000477 · PF00078
CDD
cd00304
InterPro
IPR000477
PDB
IPR000477 PF00078 (ECOD; PDBsum)
Pfam
PF00078

Topics to explore

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Overview

History

Function in viruses

In cellular life

Structure

Replication fidelity

Applications

Advanced semantic analysis

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Map overview Semantic statistics

Reverse transcriptase

Nodes97
Edges96
Triples148
Avg. degree1.98
Density0.020619
Components1

How this topic connects Entity context

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Reverse transcriptase

Top relations

related to External links · 35
Reverse transcriptase → Archived, Boehringer Ingelheim, Cold Spring Harbor Laboratory, David Baltimore, Goodsell DS, Harold Varmus, Human, John Coffin, Medical Animation, Medicine Medical Subject Headings, MeSH, Molecule, Month, National Library, Nov, Overview, P03366, PDB, PDBe-KB, Protein Data Bank
related to history · 18
Reverse transcriptase → August, David Baltimore, For, Howard Temin, Madison, Medicine, MIT, Nature, Nobel Prize, Physiology, Renato Dulbecco, Reverse, RNA, RNA-dependent DNA, Rous, The, University, Wisconsin
related to In cellular life · 13
Reverse transcriptase → Beljanski, DNA, France, In, Initial, Retrons, RNA, Romashchenko, Self-replicating, Telomerase, These, They, USSR
related to Replication fidelity · 12
Reverse transcriptase → AMV, DNA, II, Lastly, M-MLV, Mutation, Promega, Reverse, RNA, The, There, This
related to Independent artificial evolution · 9
Reverse transcriptase → All, DNA, In, It, RNA, RT-PCR, RTX, This, Tko DNA
related to Template switching · 9
Reverse transcriptase → After, From, Rawson, RNA, RNAse, Template, The, There, Two RNA
related to Function in viruses · 7
Reverse transcriptase → DNA, HIV, Reverse-transcribing DNA, Reverse-transcribing RNA, RNA, The, Without
related to Molecular biology · 7
Reverse transcriptase → DNA, PCR, Reverse, RNA, RT-PCR, RTx, The
related to Structure · 7
Reverse transcriptase → By, DNA, In, RNA, RNase, Some, The
related to Antiviral drugs · 6
Reverse transcriptase → As HIV, Collectively, Epivir, Retrovir, Viramune, Viread

Important terminology Word statistics

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Important terminology

rna reverse dna transcriptase genome primer polymerase viral template transcription viruses hiv replication genomes virus enzyme process used also two

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Reverse transcriptaseAlphaFoldIPR0004771.00infobox
Reverse transcriptaseAlphaFoldPF000781.00infobox
Reverse transcriptaseAvailable protein structures:IPR0004771.00infobox
Reverse transcriptaseAvailable protein structures:PF000781.00infobox
Reverse transcriptaseCDDcd003041.00infobox
Reverse transcriptaseInterProIPR0004771.00infobox
Reverse transcriptasePDBIPR000477 PF00078 (ECOD; PDBsum)1.00infobox
Reverse transcriptasePfamPF000781.00infobox
Reverse transcriptasePfam clanCL00271.00infobox
Reverse transcriptasePROSITEPS508781.00infobox
Reverse transcriptaseSCOP21hmv / SCOPe / SUPFAM1.00infobox
Reverse transcriptaseSymbolRVT_11.00infobox

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