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A telomere (/ˈtɛləmɪər, ˈtiːlə-/; from Ancient Greek τέλος (télos) 'end' and μέρος (méros) 'part') is a region of repetitive nucleotide sequences associated with specialized proteins at the ends of linear chromosomes (see Sequences). Telomeres are a widespread genetic feature most commonly found in eukaryotes. In most or even all species possessing them…
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telomeres dna length ends telomerase replication chromosomes cell sequences end shortening cells associated species proteins aging stress strand linear cancer
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| germ line | instance of | could extend telomeres in immortal tissues | 0.80 | text |
| cancer cells | instance of | could extend telomeres in immortal tissues | 0.80 | text |
| stem cells | instance of | could extend telomeres in immortal tissues | 0.80 | text |
| most cancer cell lines | instance of | and immortal cell populations | 0.80 | text |
| an enzyme might be activated to prevent the shortening of DNA termini with each cell division.In 1975 | instance of | and immortal cell populations | 0.80 | text |
| DNA-polymerases | instance of | G-quadruplexes present an obstacle for enzymes | 0.80 | text |
| are thus thought to be involved in the regulation of replication | instance of | G-quadruplexes present an obstacle for enzymes | 0.80 | text |
| transcription.TelomeraseMany organisms have a ribonucleoprotein enzyme called telomerase | instance of | G-quadruplexes present an obstacle for enzymes | 0.80 | text |
| which carries out the task of adding repetitive nucleotide sequences to the ends of the DNA | instance of | G-quadruplexes present an obstacle for enzymes | 0.80 | text |
| embryonic stem cells | instance of | some types of stem cells | 0.80 | text |
| and certain white blood cells | instance of | some types of stem cells | 0.80 | text |
| transcription | instance of | G-quadruplexes present an obstacle for enzymes | 0.80 | text |
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