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Ku70 is a heterodimeric protein made up of Ku70 and Ku80, which together form Ku. In humans, is encoded by the XRCC6 gene. Ku70 plays a critical role in the DNA repair, maintenance and many other cellular processes.
The analysis highlights Interactions, Function and Clinical as prominent areas in the source structure around Ku70.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Ku70 shows recurring relationship patterns in the source. For example, Ku70 → 5'-deoxyribose-5-phosphate lyase activity, activation of innate immune response, ATP binding, brain development, catalytic activity, cellular hyperosmotic salinity response, cellular response to DNA damage stimulus, cellular response to gamma radiation, cellular response to X-ray, chromosome, cyclin binding, cytoplasm, cytosol, damaged DNA binding, DNA binding, DNA duplex unwinding, DNA helicase activity, DNA ligation, DNA recombination, DNA repair Another extracted example is Ku70 → Achilles tendon, beta cell, embryo, epiblast, ganglionic eminence, genital tubercle, islet of Langerhans, left testis, neural layer of retina, otic placode, otic vesicle, right adrenal gland, right lobe of liver, right testis, saccule, tail of embryo, thymus, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
dna gene ku bp repair ku80 human chr chromosome band end protein xrcc6 22 aging role x-ray mouse maintenance location
TTTA extracted 163 structured relationships around Ku70. Examples in this analysis include Ku70 → 4.2.99.18 → ↗ and Ku70 → Aliases → XRCC6, X-ray repair complementing defective repair in Chinese hamster cells 6, CTC75, CTCBF, G22P1, KU70, ML8, TLAA, X-ray repair cross complementing 6. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Ku70 | 4.2.99.18 | ↗ | 1.00 | infobox |
| Ku70 | 5.6.2.4 | ↗ | 1.00 | infobox |
| Ku70 | Aliases | XRCC6, X-ray repair complementing defective repair in Chinese hamster cells 6, CTC75, CTCBF, G22P1, KU70, ML8, TLAA, X-ray repair cross complementing 6 | 1.00 | infobox |
| Ku70 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1JEQ, 1JEY, 1JJR, 3RZX | 1.00 | infobox |
| Ku70 | Band | 22q13.2 | 1.00 | infobox |
| Ku70 | Band | 15 E1|15 38.33 cM | 1.00 | infobox |
| Ku70 | Bgee | right testis | 1.00 | infobox |
| Ku70 | Bgee | left testis | 1.00 | infobox |
| Ku70 | Bgee | ventricular zone | 1.00 | infobox |
| Ku70 | Bgee | islet of Langerhans | 1.00 | infobox |
| Ku70 | Bgee | embryo | 1.00 | infobox |
| Ku70 | Bgee | ganglionic eminence | 1.00 | infobox |
| Ku70 | Bgee | Achilles tendon | 1.00 | infobox |
| Ku70 | Bgee | right adrenal gland | 1.00 | infobox |
| Ku70 | Bgee | thymus | 1.00 | infobox |
| Ku70 | Bgee | beta cell | 1.00 | infobox |
| Ku70 | Bgee | otic placode | 1.00 | infobox |
| Ku70 | Bgee | saccule | 1.00 | infobox |
| Ku70 | Bgee | otic vesicle | 1.00 | infobox |
| Ku70 | Bgee | neural layer of retina | 1.00 | infobox |
| Ku70 | Bgee | tail of embryo | 1.00 | infobox |
| Ku70 | Bgee | epiblast | 1.00 | infobox |
| Ku70 | Bgee | genital tubercle | 1.00 | infobox |
| Ku70 | Bgee | right lobe of liver | 1.00 | infobox |
| Ku70 | BioGPS | n/a | 1.00 | infobox |
| Ku70 | Chr. | Chromosome 22 (human) | 1.00 | infobox |
| Ku70 | Chr. | Chromosome 15 (mouse) | 1.00 | infobox |
| Ku70 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Ku70 | End | 41,664,048 bp | 1.00 | infobox |
| Ku70 | End | 81,924,286 bp | 1.00 | infobox |
The concept neighborhoods around Ku70 bring nearby vocabulary together. In this analysis, examples include Dna, Ku80 and Repair. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Ku70, one of the stronger structural bridges in this analysis connects Ku70 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Ku70 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Clinical, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Ku70 · EN edition · Analysis: TopicsToTalkAbout