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Telomerase

Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of the chromosomes of most eukaryotes. Telomeres protect the end of the chromosome from DNA damage or from fusion with neighbouring chromosomes.…

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Telomerase

Nodes173
Edges172
Triples106
Avg. degree1.99
Density0.011561
Components1

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Telomerase

Top relations

related to The telomerase complex · 30
Telomerase → CST, DKC1, DNA, Each, EM, For, GAR1, H/ACA, H2A-H2B, NHP2, NOP10, POT1, Previous, RNA, RPA-like, RPA70, TCAB1, Teb1, Teb2, Teb3
related to External links · 21
Telomerase → Archived, Gene Ontology, GO, Human Telomerase, Medicine Medical Subject Headings, MeSH, MUNElizabeth Blackburn's Seminars, National Library, O14746, Overview, PDB, PDBe-KB, Q0QHL8, Telomerase Database, TelomeraseTelomerase, Telomeres, TERT, Tribolium, UniProt, Wayback MachineThree-dimensional
related to history · 16
Telomerase → Alexey Olovnikov, Blackburn, Carol, Elizabeth Blackburn, EM, Greider, Jack, Later, Medicine, Nobel Prize, Physiology, Soviet, Szostak, Tetrahymena, The, Together
related to Cancer · 15
Telomerase → As, Cells, DNA, DSB, Eventually, Exposed, Hayflick, HeLa, In, Many, Retinoblastoma, Sometimes, This, When, With
related to Mechanism · 8
Telomerase → By, CAAUCCCAAUC-5, TERC, TERT, The, These TTAGGG, TPP1, TTAGGG
related to The catalytic protein · 6
Telomerase → B-family DNA, RNA, RNA-Binding Domain, TERT, The, TRBD
related to Aging · 5
Telomerase → At, DNA, Hayflick, In, This
related to Heart disease, diabetes and quality of life · 3
Telomerase → Across, Blackburn, In
is a · 2
Telomerase → good biomarker for cancer detection because about 85, reverse transcriptase enzyme that carries its own RNA molecule

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Important terminology

cells cancer telomeres telomere cell human htert rna activity tert also aging tumors protein dna somatic chromosomes found one study

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Telomeraseis areverse transcriptase enzyme that carries its own RNA molecule0.90text
Telomeraseis agood biomarker for cancer detection because about 850.90text
Telomeraserelated to AgingDNA0.60section
Telomeraserelated to AgingIn0.60section
Telomeraserelated to AgingHayflick0.60section
Telomeraserelated to AgingAt0.60section
Telomeraserelated to AgingThis0.60section
Telomeraserelated to CancerIn0.60section
Telomeraserelated to CancerHayflick0.60section
Telomeraserelated to CancerRetinoblastoma0.60section
Telomeraserelated to CancerCells0.60section
Telomeraserelated to CancerSometimes0.60section

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