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Conditional gene knockout

Conditional gene knockout is a technique used to eliminate a specific gene in a certain tissue, such as the liver. This technique is useful to study the role of individual genes in living organisms. It differs from traditional gene knockout because it targets specific genes at specific times rather than being deleted from beginning of life. Using the…

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Uses

AlleleMammary glandMouse brainAlzheimer's diseaseCyclin-dependent kinase 5
5 related topics

Technique

Cre-lox recombinationRecombinationTamoxifen
3 related topics

Knockout Mouse Project (KOMP)

Oliver Smithies
1 related topics

Overview

Gene knockoutEmbryonic deathMutation
3 related topics

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Overview

Technique

Uses

Knockout Mouse Project (KOMP)

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Conditional gene knockout

Nodes17
Edges16
Triples44
Avg. degree1.88
Density0.117647
Components1

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Conditional gene knockout

Top relations

related to Knockout Mouse Project (KOMP) · 23
Conditional gene knockout → All, Along, Both, Conditional, DNA, ES, For, However, January, KOMP, Lastly, Nobel, Oliver, Oliver Smithies, Other, Some, The, The KOMP, The KOMP Repository, Their
related to Technique · 12
Conditional gene knockout → An, Cre, Cre-lox, Cre-recombinase, DNA, During, Figuring, Only, The, The Cre, This, Two
related to Uses · 7
Conditional gene knockout → Alzheimer's, BRCA1, Cdk5, It, Scientists, Such, The
is a · 2
Conditional gene knockout → technique used to eliminate a specific gene in a certain tissue, time-consuming procedure and there are additional projects focusing on knocking out the remaining mouse genes

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Important terminology

gene knockout genes conditional technique specific used mouse two mice 10 study tissue traditional recombination similar komp https certain scientists

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Conditional gene knockoutis atechnique used to eliminate a specific gene in a certain tissue0.90text
Conditional gene knockoutis atime-consuming procedure and there are additional projects focusing on knocking out the remaining mouse genes0.90text
Conditional gene knockoutrelated to Knockout Mouse Project (KOMP)Conditional0.60section
Conditional gene knockoutrelated to Knockout Mouse Project (KOMP)For0.60section
Conditional gene knockoutrelated to Knockout Mouse Project (KOMP)These0.60section
Conditional gene knockoutrelated to Knockout Mouse Project (KOMP)All0.60section
Conditional gene knockoutrelated to Knockout Mouse Project (KOMP)However0.60section
Conditional gene knockoutrelated to Knockout Mouse Project (KOMP)Their0.60section
Conditional gene knockoutrelated to Knockout Mouse Project (KOMP)Along0.60section
Conditional gene knockoutrelated to Knockout Mouse Project (KOMP)The0.60section
Conditional gene knockoutrelated to Knockout Mouse Project (KOMP)KOMP0.60section
Conditional gene knockoutrelated to Knockout Mouse Project (KOMP)There0.60section

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