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PIK3R1

Phosphatidylinositol 3-kinase regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene.

Measurement, Interactions & Function

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Interactions

33 related topics

Function

7 related topics

Clinical significance

2 related topics

Overview

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Aliases
PIK3R1, AGM7, GRB1, IMD36, p85, p85-ALPHA, phosphoinositide-3-kinase regulatory subunit 1, PI3KR1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A0N, 1AZG, 1H9O, 1PBW, 1PHT, 1PIC, 1PKS, 1PKT, 2IUG, 2IUH, 2IUI, 2RD0, 2V1Y, 3HHM, 3HIZ, 3I5R, 3I5S, 4A55,…
Band
5q13.1 · 13 D1|13 53.92 cM
Bgee
Achilles tendon · caput epididymis · corpus epididymis · postcentral gyrus · lactiferous duct
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 13 (mouse)

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Overview

Function

Clinical significance

Interactions

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Map overview Semantic statistics

PIK3R1

Nodes49
Edges48
Triples184
Avg. degree1.96
Density0.040816
Components1

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PIK3R1

Top relations

Gene ontology · 82
PIK3R1 → 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-3-kinase regulator activity, axon guidance, B cell differentiation, cell-cell junction, cellular glucose homeostasis, cellular response to insulin stimulus, cellular response to UV, cis-Golgi network, cytokine-mediated signaling pathway, cytoplasm, cytosol, epidermal growth factor receptor signaling pathway, ErbB-3 class receptor binding, ERBB2 signaling pathway, extrinsic apoptotic signaling pathway via death domain receptors, Fc-epsilon receptor signaling pathway, Fc-gamma receptor signaling pathway involved in phagocytosis, G protein-coupled receptor signaling pathway, growth hormone receptor signaling pathway
related to Interactions · 30
PIK3R1 → ADAM12, BCAR1, CBL, CBLB, CD117, CD28, CD7, CENTG1, EPHA2, EPOR, ERBB3, EZR, FCGR2A, GAB1, GAB2, Grb2, HRAS, IL1R1, IRS1IRS2, JAK2
Bgee · 20
PIK3R1 → Achilles tendon, aortic valve, caput epididymis, corpus epididymis, cumulus cell, external globus pallidus, genital tubercle, intercostal muscle, lacrimal gland, lactiferous duct, middle temporal gyrus, molar, parotid gland, postcentral gyrus, Rostral migratory stream, skin of external ear, stroma of bone marrow, superior frontal gyrus, tail of epididymis, trigeminal ganglion
RNA expression pattern · 20
PIK3R1 → Achilles tendon, aortic valve, caput epididymis, corpus epididymis, cumulus cell, external globus pallidus, genital tubercle, intercostal muscle, lacrimal gland, lactiferous duct, middle temporal gyrus, molar, parotid gland, postcentral gyrus, Rostral migratory stream, skin of external ear, stroma of bone marrow, superior frontal gyrus, tail of epididymis, trigeminal ganglion
related to Function · 7
PIK3R1 → In, It, ITGB1, Phosphatidylinositol, Suppression, The, The Pik3r1
Band · 2
PIK3R1 → 13 D1|13 53.92 cM, 5q13.1
Chr. · 2
PIK3R1 → Chromosome 13 (mouse), Chromosome 5 (human)
End · 2
PIK3R1 → 101,904,725 bp, 68,301,821 bp
related to Clinical significance · 2
PIK3R1 → Mutations, SHORT
Aliases · 1
PIK3R1 → PIK3R1, AGM7, GRB1, IMD36, p85, p85-ALPHA, phosphoinositide-3-kinase regulatory subunit 1, PI3KR1

Important terminology Word statistics

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Important terminology

gene bp subunit chr human band regulatory phosphatidylinositol chromosome 3-kinase location mouse enzyme function 55 external search 301 821 end

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PIK3R1AliasesPIK3R1, AGM7, GRB1, IMD36, p85, p85-ALPHA, phosphoinositide-3-kinase regulatory subunit 1, PI3KR11.00infobox
PIK3R1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A0N, 1AZG, 1H9O, 1PBW, 1PHT, 1PIC, 1PKS, 1PKT, 2IUG, 2IUH, 2IUI, 2RD0, 2V1Y, 3HHM, 3HIZ, 3I5R, 3I5S, 4A55,…1.00infobox
PIK3R1Band5q13.11.00infobox
PIK3R1Band13 D1|13 53.92 cM1.00infobox
PIK3R1BgeeAchilles tendon1.00infobox
PIK3R1Bgeecaput epididymis1.00infobox
PIK3R1Bgeecorpus epididymis1.00infobox
PIK3R1Bgeepostcentral gyrus1.00infobox
PIK3R1Bgeelactiferous duct1.00infobox
PIK3R1Bgeetail of epididymis1.00infobox
PIK3R1Bgeetrigeminal ganglion1.00infobox
PIK3R1Bgeemiddle temporal gyrus1.00infobox
PIK3R1Bgeesuperior frontal gyrus1.00infobox
PIK3R1Bgeeexternal globus pallidus1.00infobox
PIK3R1Bgeelacrimal gland1.00infobox
PIK3R1Bgeemolar1.00infobox
PIK3R1Bgeeparotid gland1.00infobox
PIK3R1Bgeeintercostal muscle1.00infobox
PIK3R1BgeeRostral migratory stream1.00infobox
PIK3R1Bgeestroma of bone marrow1.00infobox
PIK3R1Bgeecumulus cell1.00infobox
PIK3R1Bgeegenital tubercle1.00infobox
PIK3R1Bgeeaortic valve1.00infobox
PIK3R1Bgeeskin of external ear1.00infobox
PIK3R1BioGPSMore reference expression data1.00infobox
PIK3R1Chr.Chromosome 5 (human)1.00infobox
PIK3R1Chr.Chromosome 13 (mouse)1.00infobox
PIK3R1DatabasesNCBI: entry; OMA: entry1.00infobox
PIK3R1End68,301,821 bp1.00infobox
PIK3R1End101,904,725 bp1.00infobox

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