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Factor IX (EC 3.4.21.22) is one of the serine proteases involved in coagulation; it belongs to peptidase family S1. Deficiency of this protein causes haemophilia B.
The analysis highlights Physiology, Genetics and Domain architecture as prominent areas in the source structure around Factor IX.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Factor IX shows recurring relationship patterns in the source. For example, Factor IX → blood coagulation, blood coagulation, extrinsic pathway, blood coagulation, intrinsic pathway, calcium ion binding, collagen-containing extracellular matrix, endopeptidase activity, endoplasmic reticulum lumen, endoplasmic reticulum to Golgi vesicle-mediated transport, extracellular exosome, extracellular region, extracellular space, Golgi lumen, hemostasis, hydrolase activity, metal ion binding, peptidase activity, peptidyl-glutamic acid carboxylation, plasma membrane, protein binding, proteolysis Another extracted example is Factor IX → blood, dentate gyrus, gallbladder, gonad, human musculoskeletal system, jejunum, kidney, left lobe of liver, lumbar spinal ganglion, medial head of gastrocnemius muscle, muscle, muscular system, nucleus of stria terminalis, pancreatic ductal cell, piriform cortex, right lobe of liver, secondary oocyte, sexually immature organism, skin of thigh, thoracic diaphragm. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
factor ix coagulation gene bp human domain protein chr band chromosome haemophilia list mutations deficiency blood f9 mouse binding peptidase
TTTA extracted 145 structured relationships around Factor IX. Examples in this analysis include Factor IX → 3.4.21.22 → ↗ and Factor IX → Aliases → F9, F9 p22, FIX, HEMB, P19, PTC, THPH8, coagulation factor IX, Blood coagulation factor IX, Christmas Factor. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Factor IX | 3.4.21.22 | ↗ | 1.00 | infobox |
| Factor IX | Aliases | F9, F9 p22, FIX, HEMB, P19, PTC, THPH8, coagulation factor IX, Blood coagulation factor IX, Christmas Factor | 1.00 | infobox |
| Factor IX | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CFH, 1CFI, 1EDM, 1IXA, 1MGX, 1NL0, 1RFN, 2WPH, 2WPI, 2WPJ, 2WPK, 2WPL, 2WPM, 3KCG, 3LC3, 3LC5, 4YZU, 4Z0K,… | 1.00 | infobox |
| Factor IX | Band | Xq27.1 | 1.00 | infobox |
| Factor IX | Band | X A6|X 33.5 cM | 1.00 | infobox |
| Factor IX | Bgee | right lobe of liver | 1.00 | infobox |
| Factor IX | Bgee | secondary oocyte | 1.00 | infobox |
| Factor IX | Bgee | gonad | 1.00 | infobox |
| Factor IX | Bgee | pancreatic ductal cell | 1.00 | infobox |
| Factor IX | Bgee | skin of thigh | 1.00 | infobox |
| Factor IX | Bgee | kidney | 1.00 | infobox |
| Factor IX | Bgee | blood | 1.00 | infobox |
| Factor IX | Bgee | human musculoskeletal system | 1.00 | infobox |
| Factor IX | Bgee | muscular system | 1.00 | infobox |
| Factor IX | Bgee | muscle | 1.00 | infobox |
| Factor IX | Bgee | left lobe of liver | 1.00 | infobox |
| Factor IX | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| Factor IX | Bgee | gallbladder | 1.00 | infobox |
| Factor IX | Bgee | sexually immature organism | 1.00 | infobox |
| Factor IX | Bgee | thoracic diaphragm | 1.00 | infobox |
| Factor IX | Bgee | medial head of gastrocnemius muscle | 1.00 | infobox |
| Factor IX | Bgee | dentate gyrus | 1.00 | infobox |
| Factor IX | Bgee | nucleus of stria terminalis | 1.00 | infobox |
| Factor IX | Bgee | piriform cortex | 1.00 | infobox |
| Factor IX | Bgee | jejunum | 1.00 | infobox |
| Factor IX | BioGPS | More reference expression data | 1.00 | infobox |
| Factor IX | Chr. | X chromosome (human) | 1.00 | infobox |
| Factor IX | Chr. | X chromosome (mouse) | 1.00 | infobox |
| Factor IX | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Factor IX | End | 139,563,459 bp | 1.00 | infobox |
The concept neighborhoods around Factor IX bring nearby vocabulary together. In this analysis, examples include Ix, Coagulation and List. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Factor IX, one of the stronger structural bridges in this analysis connects Factor IX with Physiology. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Factor IX to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Physiology, Genetics & Domain architecture, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Factor IX · EN edition · Analysis: TopicsToTalkAbout