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Osteocalcin

Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a small (49-amino-acid) noncollagenous protein hormone found in bone and dentin, first identified as a calcium-binding protein.

Applications, Function & Use as a biochemical marker for bone formation

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Function

14 related topics

Use as a biochemical marker for bone formation

7 related topics

Overview

9 related topics

Key facts & relationships

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Aliases
BGLAP, BGP, OC, OCN, bone gamma-carboxyglutamate protein, Osteocalcin
Band
1q22 · 3 F1|3 38.81 cM
Bgee
testicle · gonad · right hemisphere of cerebellum · C1 segment · muscle layer of sigmoid colon
BioGPS
n/a
Chr.
Chromosome 1 (human) · Chromosome 3 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Function

Use as a biochemical marker for bone formation

Advanced semantic analysis

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Map overview Semantic statistics

Osteocalcin

Nodes34
Edges33
Triples121
Avg. degree1.94
Density0.058824
Components1

How this topic connects Entity context

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Osteocalcin

Top relations

Gene ontology · 47
Osteocalcin → ageing, biomineral tissue development, bone development, bone mineralization, calcium ion binding, cell adhesion, cell projection, cellular response to growth factor stimulus, cellular response to vitamin D, cytoplasm, dendrite, endoplasmic reticulum lumen, endoplasmic reticulum to Golgi vesicle-mediated transport, extracellular region, extracellular space, Golgi apparatus, Golgi lumen, hydroxyapatite binding, metal ion binding, odontogenesis
Bgee · 20
Osteocalcin → bone marrow, C1 segment, caudate nucleus, cochlea, esophagus, gonad, lip, lymph node, morula, muscle layer of sigmoid colon, nucleus accumbens, placenta, putamen, right hemisphere of cerebellum, right uterine tube, stomach, substantia nigra, testicle, thyroid gland, white adipose tissue
RNA expression pattern · 20
Osteocalcin → bone marrow, C1 segment, caudate nucleus, cochlea, esophagus, gonad, lip, lymph node, morula, muscle layer of sigmoid colon, nucleus accumbens, placenta, putamen, right hemisphere of cerebellum, right uterine tube, stomach, substantia nigra, testicle, thyroid gland, white adipose tissue
related to External links · 9
Osteocalcin → Medicine Medical Subject Headings, MeSH, National Library, Overview, PDB, PDBe-KB, Pig Osteocalcin, Q8HYY9, UniProt
related to Use as a biochemical marker for bone formation · 4
Osteocalcin → As, For, Higher, In
Band · 2
Osteocalcin → 1q22, 3 F1|3 38.81 cM
Chr. · 2
Osteocalcin → Chromosome 1 (human), Chromosome 3 (mouse)
End · 2
Osteocalcin → 156,243,317 bp, 88,280,050 bp
Aliases · 1
Osteocalcin → BGLAP, BGP, OC, OCN, bone gamma-carboxyglutamate protein, Osteocalcin
BioGPS · 1
Osteocalcin → n/a

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Important terminology

bone bp bglap chr human band gene chromosome formation protein hormone location insulin acts third receptor mouse muscle levels vitamin

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
OsteocalcinAliasesBGLAP, BGP, OC, OCN, bone gamma-carboxyglutamate protein, Osteocalcin1.00infobox
OsteocalcinBand1q221.00infobox
OsteocalcinBand3 F1|3 38.81 cM1.00infobox
OsteocalcinBgeetesticle1.00infobox
OsteocalcinBgeegonad1.00infobox
OsteocalcinBgeeright hemisphere of cerebellum1.00infobox
OsteocalcinBgeeC1 segment1.00infobox
OsteocalcinBgeemuscle layer of sigmoid colon1.00infobox
OsteocalcinBgeeputamen1.00infobox
OsteocalcinBgeesubstantia nigra1.00infobox
OsteocalcinBgeecaudate nucleus1.00infobox
OsteocalcinBgeenucleus accumbens1.00infobox
OsteocalcinBgeeright uterine tube1.00infobox
OsteocalcinBgeeesophagus1.00infobox
OsteocalcinBgeecochlea1.00infobox
OsteocalcinBgeelip1.00infobox
OsteocalcinBgeeplacenta1.00infobox
OsteocalcinBgeelymph node1.00infobox
OsteocalcinBgeestomach1.00infobox
OsteocalcinBgeewhite adipose tissue1.00infobox
OsteocalcinBgeethyroid gland1.00infobox
OsteocalcinBgeemorula1.00infobox
OsteocalcinBgeebone marrow1.00infobox
OsteocalcinBioGPSn/a1.00infobox
OsteocalcinChr.Chromosome 1 (human)1.00infobox
OsteocalcinChr.Chromosome 3 (mouse)1.00infobox
OsteocalcinDatabasesNCBI: entry; OMA: entry1.00infobox
OsteocalcinEnd156,243,317 bp1.00infobox
OsteocalcinEnd88,280,050 bp1.00infobox
OsteocalcinEnsemblENSG000002422521.00infobox

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