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Protein kinase C epsilon type (PKCε) is an enzyme that in humans is encoded by the PRKCE gene. PKCε is an isoform of the large PKC family of protein kinases that play many roles in different tissues. In cardiac muscle cells, PKCε regulates muscle contraction through its actions at sarcomeric proteins, and PKCε modulates cardiac cell metabolism through…
The analysis highlights Standards, Structure and Function as prominent areas in the source structure around PRKCE.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PRKCE shows recurring relationship patterns in the source. For example, PRKCE → 14-3-3 protein binding, actin monomer binding, apoptotic process, ATP binding, calcium-independent protein kinase C activity, cell adhesion, cell cycle, cell division, cell periphery, cellular response to ethanol, cellular response to hypoxia, cellular response to prostaglandin E stimulus, cytoplasm, cytoskeleton, cytosol, endoplasmic reticulum, enzyme activator activity, enzyme binding, ethanol binding, Fc-gamma receptor signaling pathway involved in phagocytosis Another extracted example is PRKCE → C-kinase, C1, C2, Ensembl ID, ENSG00000171132, Human PRKCE, It, PKC, PKC-δ, PKCε, Q02156, RACK, RACK/RACK2, RACK1, Receptors, Serine-729, The, The PKC, Threonine-566, Threonine-710. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
pkcε protein cardiac pkc phosphorylation also mitochondrial kinase cardioprotection gene studies human function ctni preconditioning hypertrophy following bp isoform mitochondria
TTTA extracted 160 structured relationships around PRKCE. Examples in this analysis include PRKCE → 2.7.11.13 → ↗ and PRKCE → Aliases → PRKCE, PKCE, nPKC-epsilon, protein kinase C epsilon. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PRKCE | 2.7.11.13 | ↗ | 1.00 | infobox |
| PRKCE | Aliases | PRKCE, PKCE, nPKC-epsilon, protein kinase C epsilon | 1.00 | infobox |
| PRKCE | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2WH0 | 1.00 | infobox |
| PRKCE | Band | 2p21 | 1.00 | infobox |
| PRKCE | Band | 17|17 E4 | 1.00 | infobox |
| PRKCE | Bgee | buccal mucosa cell | 1.00 | infobox |
| PRKCE | Bgee | sural nerve | 1.00 | infobox |
| PRKCE | Bgee | lateral nuclear group of thalamus | 1.00 | infobox |
| PRKCE | Bgee | parietal lobe | 1.00 | infobox |
| PRKCE | Bgee | postcentral gyrus | 1.00 | infobox |
| PRKCE | Bgee | right lung | 1.00 | infobox |
| PRKCE | Bgee | middle temporal gyrus | 1.00 | infobox |
| PRKCE | Bgee | sperm | 1.00 | infobox |
| PRKCE | Bgee | superior frontal gyrus | 1.00 | infobox |
| PRKCE | Bgee | entorhinal cortex | 1.00 | infobox |
| PRKCE | Bgee | anterior amygdaloid area | 1.00 | infobox |
| PRKCE | Bgee | subiculum | 1.00 | infobox |
| PRKCE | Bgee | lateral septal nucleus | 1.00 | infobox |
| PRKCE | Bgee | olfactory tubercle | 1.00 | infobox |
| PRKCE | Bgee | dentate gyrus | 1.00 | infobox |
| PRKCE | Bgee | prefrontal cortex | 1.00 | infobox |
| PRKCE | Bgee | hippocampus proper | 1.00 | infobox |
| PRKCE | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| PRKCE | Bgee | ventromedial nucleus | 1.00 | infobox |
| PRKCE | Bgee | medial dorsal nucleus | 1.00 | infobox |
| PRKCE | BioGPS | More reference expression data | 1.00 | infobox |
| PRKCE | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| PRKCE | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| PRKCE | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PRKCE | End | 46,187,990 bp | 1.00 | infobox |
The concept neighborhoods around PRKCE bring nearby vocabulary together. In this analysis, examples include Gene, Bp and Chr. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PRKCE, one of the stronger structural bridges in this analysis connects PRKCE with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PRKCE to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Structure & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PRKCE · EN edition · Analysis: TopicsToTalkAbout