PRKCE

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Export map as:

Research this topic

Explore the main themes, entities and connections around PRKCE. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Structure

Protein Serine Threonine Kinase Primary structure

29 related topics

Function

Diacylglycerol Phorbol Apoptosis Ischemia Heat shock

46 related topics

Clinical significance

CMyBPC Myotrophin Hypertension Heart failure FAK

22 related topics

Substrates and interactions

Ion channels Cytoskeletal Interact ACTA1 COPB2

10 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.13: ↗
Aliases: PRKCE, PKCE, nPKC-epsilon, protein kinase C epsilon
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2WH0
Band: 2p21 · 17|17 E4
Bgee: buccal mucosa cell · sural nerve · lateral nuclear group of thalamus · parietal lobe · postcentral gyrus
BioGPS: More reference expression data

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Substrates and interactions

Ion channels Ion channel
Cytoskeletal
Interact Protein-protein interaction
ACTA1 Actin, alpha 1
COPB2
CFTR Cystic fibrosis transmembrane conductance regulator
KRT1 Keratin 1
GNB2L1
MYH9
YWHAZ

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes126

Edges125

Triples160

Avg. degree1.98

Density0.015873

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

PRKCE

Top relations

Gene ontology · 71

PRKCE → 14-3-3 protein binding, actin monomer binding, apoptotic process, ATP binding, calcium-independent protein kinase C activity, cell adhesion, cell cycle, cell division, cell periphery, cellular response to ethanol, cellular response to hypoxia, cellular response to prostaglandin E stimulus, cytoplasm, cytoskeleton, cytosol, endoplasmic reticulum, enzyme activator activity, enzyme binding, ethanol binding, Fc-gamma receptor signaling pathway involved in phagocytosis

related to Structure · 21

PRKCE → C-kinase, C1, C2, Ensembl ID, ENSG00000171132, Human PRKCE, It, PKC, PKC-δ, PKCε, Q02156, RACK, RACK/RACK2, RACK1, Receptors, Serine-729, The, The PKC, Threonine-566, Threonine-710

Bgee · 20

PRKCE → anterior amygdaloid area, buccal mucosa cell, dentate gyrus, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, hippocampus proper, lateral nuclear group of thalamus, lateral septal nucleus, medial dorsal nucleus, middle temporal gyrus, olfactory tubercle, parietal lobe, postcentral gyrus, prefrontal cortex, right lung, sperm, subiculum, superior frontal gyrus, sural nerve, ventromedial nucleus

RNA expression pattern · 20

Band · 2

PRKCE → 17|17 E4, 2p21

Chr. · 2

PRKCE → Chromosome 17 (mouse), Chromosome 2 (human)

End · 2

PRKCE → 46,187,990 bp, 86,965,347 bp

2.7.11.13 · 1

PRKCE → ↗

Aliases · 1

PRKCE → PRKCE, PKCE, nPKC-epsilon, protein kinase C epsilon

Available structures · 1

PRKCE → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2WH0

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

pkcε protein cardiac pkc phosphorylation also mitochondrial kinase cardioprotection gene studies human function ctni preconditioning hypertrophy following bp isoform mitochondria

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
PRKCE	2.7.11.13	↗	1.00	infobox
PRKCE	Aliases	PRKCE, PKCE, nPKC-epsilon, protein kinase C epsilon	1.00	infobox
PRKCE	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2WH0	1.00	infobox
PRKCE	Band	2p21	1.00	infobox
PRKCE	Band	17\|17 E4	1.00	infobox
PRKCE	Bgee	buccal mucosa cell	1.00	infobox
PRKCE	Bgee	sural nerve	1.00	infobox
PRKCE	Bgee	lateral nuclear group of thalamus	1.00	infobox
PRKCE	Bgee	parietal lobe	1.00	infobox
PRKCE	Bgee	postcentral gyrus	1.00	infobox
PRKCE	Bgee	right lung	1.00	infobox
PRKCE	Bgee	middle temporal gyrus	1.00	infobox
PRKCE	Bgee	sperm	1.00	infobox
PRKCE	Bgee	superior frontal gyrus	1.00	infobox
PRKCE	Bgee	entorhinal cortex	1.00	infobox
PRKCE	Bgee	anterior amygdaloid area	1.00	infobox
PRKCE	Bgee	subiculum	1.00	infobox
PRKCE	Bgee	lateral septal nucleus	1.00	infobox
PRKCE	Bgee	olfactory tubercle	1.00	infobox
PRKCE	Bgee	dentate gyrus	1.00	infobox
PRKCE	Bgee	prefrontal cortex	1.00	infobox
PRKCE	Bgee	hippocampus proper	1.00	infobox
PRKCE	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
PRKCE	Bgee	ventromedial nucleus	1.00	infobox
PRKCE	Bgee	medial dorsal nucleus	1.00	infobox
PRKCE	BioGPS	More reference expression data	1.00	infobox
PRKCE	Chr.	Chromosome 2 (human)	1.00	infobox
PRKCE	Chr.	Chromosome 17 (mouse)	1.00	infobox
PRKCE	Databases	NCBI: entry; OMA: entry	1.00	infobox
PRKCE	End	46,187,990 bp	1.00	infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

Connections between topic areas Semantic bridges

Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

Min side: 3