Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

ACTC1

ACTC1 encodes cardiac muscle alpha actin. This isoform differs from the alpha actin that is expressed in skeletal muscle, ACTA1. Alpha cardiac actin is the major protein of the thin filament in cardiac sarcomeres, which are responsible for muscle contraction and generation of force to support the pump function of the heart.

Art & Standards

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around ACTC1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ACTC1, ACTC, ASD5, CMD1R, CMH11, LVNC4, actin, alpha, cardiac muscle 1, actin alpha cardiac muscle 1
Band
15q14 · 2 E4|2 57.55 cM
Bgee
myocardium of left ventricle · right ventricle · cardiac muscle tissue of right atrium · right auricle of heart · apex of heart
BioGPS
More reference expression data
Chr.
Chromosome 15 (human) · Chromosome 2 (mouse)
Databases
NCBI: entry; OMA: entry

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

ACTC1

Nodes24
Edges23
Triples126
Avg. degree1.92
Density0.083333
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

ACTC1

Top relations

Gene ontology · 36
ACTC1 → actin filament, actin filament organization, actin filament-based movement, actin-mediated cell contraction, actin-myosin filament sliding, actomyosin structure organization, apoptotic process, ATP binding, ATPase activity, blood microparticle, cardiac muscle contraction, cardiac muscle tissue morphogenesis, cardiac myofibril assembly, cell body, cytoplasm, cytoskeleton, cytosol, extracellular exosome, extracellular space, filopodium
Bgee · 20
ACTC1 → apex of heart, atrioventricular valve, atrium, cardiac muscle tissue of left ventricle, cardiac muscle tissue of right atrium, digastric muscle, endocardial cushion, extraocular muscle, glutes, human fetus, interventricular septum, myocardium of left ventricle, popliteal artery, right auricle of heart, right ventricle, seminal vesicula, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle, vena cava
RNA expression pattern · 20
ACTC1 → apex of heart, atrioventricular valve, atrium, cardiac muscle tissue of left ventricle, cardiac muscle tissue of right atrium, digastric muscle, endocardial cushion, extraocular muscle, glutes, human fetus, interventricular septum, myocardium of left ventricle, popliteal artery, right auricle of heart, right ventricle, seminal vesicula, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle, vena cava
related to Structure · 16
ACTC1 → ACTA1, Actins, ACTN2, Asp4Glu, Both, Cardiac, Each, F-actin, G-actin, Glu5Asp, Kabsch, Leu301Met, Polymerization, Ser360Thr, The, Z-lines
related to Clinical significance · 6
ACTC1 → Another, Further, Japanese, Polymorphisms, South Africa, The E101K
related to External links · 4
ACTC1 → COPaKBGeneReviews/NIH/NCBI/UW, Familial Hypertrophic Cardiomyopathy OverviewHuman, Mass, UCSC Genome Browser
related to Function · 4
ACTC1 → Actin, Experiments, It, Myosin
Band · 2
ACTC1 → 15q14, 2 E4|2 57.55 cM
Chr. · 2
ACTC1 → Chromosome 15 (human), Chromosome 2 (mouse)
End · 2
ACTC1 → 113,884,029 bp, 34,795,549 bp

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

actin alpha cardiac muscle bp human gene chr band chromosome 15 protein filament location structure function skeletal amino mouse acta1

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ACTC1AliasesACTC1, ACTC, ASD5, CMD1R, CMH11, LVNC4, actin, alpha, cardiac muscle 1, actin alpha cardiac muscle 11.00infobox
ACTC1Band15q141.00infobox
ACTC1Band2 E4|2 57.55 cM1.00infobox
ACTC1Bgeemyocardium of left ventricle1.00infobox
ACTC1Bgeeright ventricle1.00infobox
ACTC1Bgeecardiac muscle tissue of right atrium1.00infobox
ACTC1Bgeeright auricle of heart1.00infobox
ACTC1Bgeeapex of heart1.00infobox
ACTC1Bgeevena cava1.00infobox
ACTC1Bgeeglutes1.00infobox
ACTC1Bgeeseminal vesicula1.00infobox
ACTC1Bgeetibialis anterior muscle1.00infobox
ACTC1Bgeepopliteal artery1.00infobox
ACTC1Bgeeatrioventricular valve1.00infobox
ACTC1Bgeeendocardial cushion1.00infobox
ACTC1Bgeecardiac muscle tissue of left ventricle1.00infobox
ACTC1Bgeeatrium1.00infobox
ACTC1Bgeeinterventricular septum1.00infobox
ACTC1Bgeevastus lateralis muscle1.00infobox
ACTC1Bgeetriceps brachii muscle1.00infobox
ACTC1Bgeehuman fetus1.00infobox
ACTC1Bgeeextraocular muscle1.00infobox
ACTC1Bgeedigastric muscle1.00infobox
ACTC1BioGPSMore reference expression data1.00infobox
ACTC1Chr.Chromosome 15 (human)1.00infobox
ACTC1Chr.Chromosome 2 (mouse)1.00infobox
ACTC1DatabasesNCBI: entry; OMA: entry1.00infobox
ACTC1End34,795,549 bp1.00infobox
ACTC1End113,884,029 bp1.00infobox
ACTC1EnsemblENSG000001592511.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.