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ACTC1: Art & Standards

ACTC1 encodes cardiac muscle alpha actin. This isoform differs from the alpha actin that is expressed in skeletal muscle, ACTA1. Alpha cardiac actin is the major protein of the thin filament in cardiac sarcomeres, which are responsible for muscle contraction and generation of force to support the pump function of the heart.

Language: English [EN]
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ACTC1 topic overview

The analysis highlights Art and Standards as prominent areas in the source structure around ACTC1.

Related topics
19
Source areas
4
Connected nodes
23
Extracted relationships
126
Concept neighborhoods
8
Bridge connections
23

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure · 11 topics
Clinical significance · 5 topics
Function · 2 topics
Overview · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ACTC1, ACTC, ASD5, CMD1R, CMH11, LVNC4, actin, alpha, cardiac muscle 1, actin alpha cardiac muscle 1
Band
15q14 · 2 E4|2 57.55 cM
Bgee
myocardium of left ventricle · right ventricle · cardiac muscle tissue of right atrium · right auricle of heart · apex of heart
BioGPS
More reference expression data
Chr.
Chromosome 15 (human) · Chromosome 2 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ACTC1 connects Entity context

The extracted context around ACTC1 shows recurring relationship patterns in the source. For example, ACTC1 → actin filament, actin filament organization, actin filament-based movement, actin-mediated cell contraction, actin-myosin filament sliding, actomyosin structure organization, apoptotic process, ATP binding, ATPase activity, blood microparticle, cardiac muscle contraction, cardiac muscle tissue morphogenesis, cardiac myofibril assembly, cell body, cytoplasm, cytoskeleton, cytosol, extracellular exosome, extracellular space, filopodium Another extracted example is ACTC1 → apex of heart, atrioventricular valve, atrium, cardiac muscle tissue of left ventricle, cardiac muscle tissue of right atrium, digastric muscle, endocardial cushion, extraocular muscle, glutes, human fetus, interventricular septum, myocardium of left ventricle, popliteal artery, right auricle of heart, right ventricle, seminal vesicula, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle, vena cava. Use these groups to spot repeated connection types before inspecting the individual relationships.

ACTC1

Top relations

Gene ontology · 36
ACTC1 → actin filament, actin filament organization, actin filament-based movement, actin-mediated cell contraction, actin-myosin filament sliding, actomyosin structure organization, apoptotic process, ATP binding, ATPase activity, blood microparticle, cardiac muscle contraction, cardiac muscle tissue morphogenesis, cardiac myofibril assembly, cell body, cytoplasm, cytoskeleton, cytosol, extracellular exosome, extracellular space, filopodium
Bgee · 20
ACTC1 → apex of heart, atrioventricular valve, atrium, cardiac muscle tissue of left ventricle, cardiac muscle tissue of right atrium, digastric muscle, endocardial cushion, extraocular muscle, glutes, human fetus, interventricular septum, myocardium of left ventricle, popliteal artery, right auricle of heart, right ventricle, seminal vesicula, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle, vena cava
RNA expression pattern · 20
ACTC1 → apex of heart, atrioventricular valve, atrium, cardiac muscle tissue of left ventricle, cardiac muscle tissue of right atrium, digastric muscle, endocardial cushion, extraocular muscle, glutes, human fetus, interventricular septum, myocardium of left ventricle, popliteal artery, right auricle of heart, right ventricle, seminal vesicula, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle, vena cava
related to Structure · 16
ACTC1 → ACTA1, Actins, ACTN2, Asp4Glu, Both, Cardiac, Each, F-actin, G-actin, Glu5Asp, Kabsch, Leu301Met, Polymerization, Ser360Thr, The, Z-lines
related to Clinical significance · 6
ACTC1 → Another, Further, Japanese, Polymorphisms, South Africa, The E101K
related to External links · 4
ACTC1 → COPaKBGeneReviews/NIH/NCBI/UW, Familial Hypertrophic Cardiomyopathy OverviewHuman, Mass, UCSC Genome Browser
related to Function · 4
ACTC1 → Actin, Experiments, It, Myosin
Band · 2
ACTC1 → 15q14, 2 E4|2 57.55 cM
Chr. · 2
ACTC1 → Chromosome 15 (human), Chromosome 2 (mouse)
End · 2
ACTC1 → 113,884,029 bp, 34,795,549 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

actin alpha cardiac muscle bp human gene chr band chromosome 15 protein filament location structure function skeletal amino mouse acta1

ACTC1 relationships Subject–Predicate–Object triples

TTTA extracted 126 structured relationships around ACTC1. Examples in this analysis include ACTC1 → Aliases → ACTC1, ACTC, ASD5, CMD1R, CMH11, LVNC4, actin, alpha, cardiac muscle 1, actin alpha cardiac muscle 1 and ACTC1 → Band → 15q14. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ACTC1AliasesACTC1, ACTC, ASD5, CMD1R, CMH11, LVNC4, actin, alpha, cardiac muscle 1, actin alpha cardiac muscle 11.00infobox
ACTC1Band15q141.00infobox
ACTC1Band2 E4|2 57.55 cM1.00infobox
ACTC1Bgeemyocardium of left ventricle1.00infobox
ACTC1Bgeeright ventricle1.00infobox
ACTC1Bgeecardiac muscle tissue of right atrium1.00infobox
ACTC1Bgeeright auricle of heart1.00infobox
ACTC1Bgeeapex of heart1.00infobox
ACTC1Bgeevena cava1.00infobox
ACTC1Bgeeglutes1.00infobox
ACTC1Bgeeseminal vesicula1.00infobox
ACTC1Bgeetibialis anterior muscle1.00infobox
ACTC1Bgeepopliteal artery1.00infobox
ACTC1Bgeeatrioventricular valve1.00infobox
ACTC1Bgeeendocardial cushion1.00infobox
ACTC1Bgeecardiac muscle tissue of left ventricle1.00infobox
ACTC1Bgeeatrium1.00infobox
ACTC1Bgeeinterventricular septum1.00infobox
ACTC1Bgeevastus lateralis muscle1.00infobox
ACTC1Bgeetriceps brachii muscle1.00infobox
ACTC1Bgeehuman fetus1.00infobox
ACTC1Bgeeextraocular muscle1.00infobox
ACTC1Bgeedigastric muscle1.00infobox
ACTC1BioGPSMore reference expression data1.00infobox
ACTC1Chr.Chromosome 15 (human)1.00infobox
ACTC1Chr.Chromosome 2 (mouse)1.00infobox
ACTC1DatabasesNCBI: entry; OMA: entry1.00infobox
ACTC1End34,795,549 bp1.00infobox
ACTC1End113,884,029 bp1.00infobox
ACTC1EnsemblENSG000001592511.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ACTC1 bring nearby vocabulary together. In this analysis, examples include Gene, Cardiac and Alpha. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • ACTC1
    • Gene
    • Cardiac
    • Alpha
    • Location
    • Human
    • Muscle
    • Cardiomyopathy
    • Function
    • Skeletal
    • Amino
    • Chromosome
    • Structure
  • actc1
    • Gene
    • Cardiac
    • Alpha
    • Location
    • Human
    • Muscle
    • Cardiomyopathy
    • Function
    • Skeletal
    • Amino
    • Chromosome
    • Structure
  • function
    • Heart
    • Thin
    • Muscle
    • Protein
    • Chromosome
    • Location
    • Structure
    • Bp
    • Chr
    • External
    • Human
    • Gene
  • acta1
    • Skeletal
    • Expressed
    • Alpha
    • Amino
    • Cardiac
    • Muscle
    • Actc1
    • Actin
  • sarcomere
    • Thin
    • Skeletal
    • Structure
  • dilated cardiomyopathy
    • Location
    • Human
    • Gene
  • hypertrophic cardiomyopathy
    • Location
    • Human
    • Gene
  • structure
    • Thin
    • Sub-domain

Connections between topic areas Semantic bridges

For ACTC1, one of the stronger structural bridges in this analysis connects ACTC1 with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ACTC1Structure · splits 12 ⟂ 12
ACTC1Clinical significance · splits 18 ⟂ 6
ACTC1Function · splits 21 ⟂ 3

Map overview Semantic statistics

ACTC1

Nodes24
Edges23
Triples126
Avg. degree1.92
Density0.083333
Components1

Source & methodology

TTTA analyzes the structure around ACTC1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ACTC1 · EN edition · Analysis: TopicsToTalkAbout

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