Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

MYL2: Standards, Function & Structure

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) also known as the regulatory light chain of myosin (RLC) is a protein that in humans is encoded by the MYL2 gene. This cardiac ventricular RLC isoform is distinct from that expressed in skeletal muscle (MYLPF), smooth muscle (MYL12B) and cardiac atrial muscle (MYL7).

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

MYL2 topic overview

The analysis highlights Standards, Function and Structure as prominent areas in the source structure around MYL2.

Related topics
31
Source areas
4
Connected nodes
35
Extracted relationships
126
Concept neighborhoods
11
Bridge connections
35

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 21 topics
Overview · 6 topics
Structure · 3 topics
Clinical significance · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MYL2, CMH10, MLC2, MLC-2s/v, myosin light chain 2, MFM12
Band
12q24.11 · 5|5 F
Bgee
right ventricle · apex of heart · thoracic diaphragm · Skeletal muscle tissue of biceps brachii · Skeletal muscle tissue of rectus abdominis
BioGPS
More reference expression data
Chr.
Chromosome 12 (human) · Chromosome 5 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Clinical significance

  • FHC Hypertrophic cardiomyopathy

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MYL2 connects Entity context

The extracted context around MYL2 shows recurring relationship patterns in the source. For example, MYL2 → A band, actin cytoskeleton, actin monomer binding, calcium ion binding, cardiac muscle contraction, cardiac myofibril, cardiac myofibril assembly, cytoplasm, cytoskeleton, cytosol, development of the heart, heart contraction, heart morphogenesis, metal ion binding, muscle cell fate specification, muscle filament sliding, myofibril, myosin complex, myosin heavy chain binding, negative regulation of cell growth Another extracted example is MYL2 → Altogether, Consistent, D166V, E12, FHC, FHC-associated MLC-2v, Furthermore, In, Loss, MLC-2, MLC-2v, MLC-2v R58Q, MLC2v, MLC2v Ser14Ala/Ser15Ala, MLCK, More, Ser14/Ser15, Similarly, The, These. Use these groups to spot repeated connection types before inspecting the individual relationships.

MYL2

Top relations

Gene ontology · 28
MYL2 → A band, actin cytoskeleton, actin monomer binding, calcium ion binding, cardiac muscle contraction, cardiac myofibril, cardiac myofibril assembly, cytoplasm, cytoskeleton, cytosol, development of the heart, heart contraction, heart morphogenesis, metal ion binding, muscle cell fate specification, muscle filament sliding, myofibril, myosin complex, myosin heavy chain binding, negative regulation of cell growth
related to Animal studies · 21
MYL2 → Altogether, Consistent, D166V, E12, FHC, FHC-associated MLC-2v, Furthermore, In, Loss, MLC-2, MLC-2v, MLC-2v R58Q, MLC2v, MLC2v Ser14Ala/Ser15Ala, MLCK, More, Ser14/Ser15, Similarly, The, These
Bgee · 19
MYL2 → ankle, aortic valve, apex of heart, atrioventricular valve, cardiac muscle tissue of left ventricle, deltoid muscle, endocardial cushion, glutes, interventricular septum, muscle of thigh, plantaris muscle, right ventricle, semi-lunar valve, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, thoracic diaphragm, tibialis anterior muscle, triceps brachii muscle
RNA expression pattern · 19
MYL2 → ankle, aortic valve, apex of heart, atrioventricular valve, cardiac muscle tissue of left ventricle, deltoid muscle, endocardial cushion, glutes, interventricular septum, muscle of thigh, plantaris muscle, right ventricle, semi-lunar valve, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, thoracic diaphragm, tibialis anterior muscle, triceps brachii muscle
related to Clinical significance · 19
MYL2 → A13T, D166V, E22K, F18L, FHC, Functional, IVS5-2-are, IVS5-2A, IVS6-1G, L103E, Mutations, N47K, N47K-have, P95A, R58Q, RLC, Ten FHC, The, Three
Band · 2
MYL2 → 12q24.11, 5|5 F
Chr. · 2
MYL2 → Chromosome 12 (human), Chromosome 5 (mouse)
End · 2
MYL2 → 110,921,443 bp, 122,113,472 bp
Aliases · 1
MYL2 → MYL2, CMH10, MLC2, MLC-2s/v, myosin light chain 2, MFM12
BioGPS · 1
MYL2 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cardiac phosphorylation myosin mlc-2v rlc muscle ventricular human chain studies light protein heart mouse role bp function also fhc chr

MYL2 relationships Subject–Predicate–Object triples

TTTA extracted 126 structured relationships around MYL2. Examples in this analysis include MYL2 → Aliases → MYL2, CMH10, MLC2, MLC-2s/v, myosin light chain 2, MFM12 and MYL2 → Band → 12q24.11. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MYL2AliasesMYL2, CMH10, MLC2, MLC-2s/v, myosin light chain 2, MFM121.00infobox
MYL2Band12q24.111.00infobox
MYL2Band5|5 F1.00infobox
MYL2Bgeeright ventricle1.00infobox
MYL2Bgeeapex of heart1.00infobox
MYL2Bgeethoracic diaphragm1.00infobox
MYL2BgeeSkeletal muscle tissue of biceps brachii1.00infobox
MYL2BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
MYL2Bgeemuscle of thigh1.00infobox
MYL2Bgeetibialis anterior muscle1.00infobox
MYL2Bgeeglutes1.00infobox
MYL2Bgeetriceps brachii muscle1.00infobox
MYL2Bgeedeltoid muscle1.00infobox
MYL2Bgeecardiac muscle tissue of left ventricle1.00infobox
MYL2Bgeeinterventricular septum1.00infobox
MYL2Bgeeatrioventricular valve1.00infobox
MYL2Bgeesoleus muscle1.00infobox
MYL2Bgeeplantaris muscle1.00infobox
MYL2Bgeeendocardial cushion1.00infobox
MYL2Bgeesemi-lunar valve1.00infobox
MYL2Bgeeaortic valve1.00infobox
MYL2Bgeeankle1.00infobox
MYL2BioGPSMore reference expression data1.00infobox
MYL2Chr.Chromosome 12 (human)1.00infobox
MYL2Chr.Chromosome 5 (mouse)1.00infobox
MYL2DatabasesNCBI: entry; OMA: entry1.00infobox
MYL2End110,921,443 bp1.00infobox
MYL2End122,113,472 bp1.00infobox
MYL2EnsemblENSG000001112451.00infobox
MYL2Entrez46331.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around MYL2 bring nearby vocabulary together. In this analysis, examples include Gene, Chromosome and Contraction. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MYL2
    • Gene
    • Chromosome
    • Contraction
    • Ventricular
    • Bp
    • Chr
    • Development
    • Function
    • Myosin
    • Protein
    • Mouse
    • Human
  • myl2
    • Gene
    • Chromosome
    • Contraction
    • Ventricular
    • Bp
    • Chr
    • Development
    • Function
    • Myosin
    • Protein
    • Mouse
    • Human
  • cardiac contractility
    • Myosin
    • Phosphorylation
    • Mlc-2v
    • Muscle
    • Chain
    • Light
    • Ventricular
    • Rlc
    • Role
    • Heart
    • Development
    • Mlck
  • cardiac myosin binding protein c
    • Calcium
    • Binding
    • Protein
    • Rlc
    • Cardiac
    • Myosin
    • Muscle
    • Skeletal
    • Phosphorylation
    • Mlc-2v
    • Ventricular
    • Chain
  • cardiac troponin i
    • Myosin
    • Phosphorylation
    • Mlc-2v
    • Muscle
    • Chain
    • Light
    • Ventricular
    • Rlc
    • Role
    • Heart
    • Development
    • Mlck
  • left ventricular hypertrophy
    • Chain
    • Response
    • Light
    • Muscle
    • Myosin
    • Mouse
    • Myl2
    • Kinase
    • Cardiac
    • Mlck
    • Associated
    • Gene
  • function
    • Development
    • Chromosome
    • Contraction
    • Gene
    • Role
    • Bp
    • Chr
    • Muscle
    • Myl2
    • Studies
    • Torsion
    • Protein
  • gene
    • Chromosome
    • Bp
    • Chr
    • Myl2
    • Band
    • Contraction
    • Development
    • Human
    • Function
    • Muscle
    • Protein
    • Mouse

Connections between topic areas Semantic bridges

For MYL2, one of the stronger structural bridges in this analysis connects MYL2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MYL2Function · splits 14 ⟂ 22
MYL2Overview · splits 29 ⟂ 7
MYL2Structure · splits 32 ⟂ 4

Map overview Semantic statistics

MYL2

Nodes36
Edges35
Triples126
Avg. degree1.94
Density0.055556
Components1

Source & methodology

TTTA analyzes the structure around MYL2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Function & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MYL2 · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.