TPM1

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TPM1 topic overview

The analysis highlights Structure, Function and Clinical Significance as prominent areas in the source structure around TPM1.

Related topics: 13
Source areas: 4
Connected nodes: 17
Extracted relationships: 121
Concept neighborhoods: 7
Bridge connections: 17

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure · 5 topics

Clinical Significance · 3 topics

Function · 3 topics

Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: TPM1, C15orf13, CMD1Y, CMH3, HTM-alpha, LVNC9, TMSA, HEL-S-265, tropomyosin 1 (alpha), tropomyosin 1
Band: 15q22.2 · 9 C|9 36.27 cM
Bgee: myocardium of left ventricle · right ventricle · atrium · right auricle of heart · seminal vesicula
BioGPS: More reference expression data
Chr.: Chromosome 15 (human) · Chromosome 9 (mouse)
Databases: NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Actin ACTC1
Myosin MYH7
Troponin T TNNT2

Clinical Significance

Hypertrophic cardiomyopathy
Dilated cardiomyopathy
Left ventricular noncompaction cardiomyopathy Noncompaction cardiomyopathy

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How TPM1 connects Entity context

The extracted context around TPM1 shows recurring relationship patterns in the source. For example, TPM1 → actin binding, actin cytoskeleton, actin filament, actin filament binding, actin filament organization, bleb, cardiac muscle contraction, cellular response to reactive oxygen species, cytoplasm, cytoskeletal protein binding, cytoskeleton, cytoskeleton organization, cytosol, filamentous actin, identical protein binding, in utero embryonic development, muscle contraction, muscle filament sliding, muscle thin filament tropomyosin, myofibril Another extracted example is TPM1 → ankle, aortic valve, apex of heart, ascending aorta, atrium, cardiac muscle tissue of right atrium, masseter muscle, medial head of gastrocnemius muscle, muscle layer of sigmoid colon, muscle of thigh, myocardium of left ventricle, right auricle of heart, right ventricle, saphenous vein, seminal vesicula, Skeletal muscle tissue of rectus abdominis, sternocleidomastoid muscle, tail of embryo, temporal muscle, triceps brachii muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 42

TPM1 → actin binding, actin cytoskeleton, actin filament, actin filament binding, actin filament organization, bleb, cardiac muscle contraction, cellular response to reactive oxygen species, cytoplasm, cytoskeletal protein binding, cytoskeleton, cytoskeleton organization, cytosol, filamentous actin, identical protein binding, in utero embryonic development, muscle contraction, muscle filament sliding, muscle thin filament tropomyosin, myofibril

Bgee · 20

TPM1 → ankle, aortic valve, apex of heart, ascending aorta, atrium, cardiac muscle tissue of right atrium, masseter muscle, medial head of gastrocnemius muscle, muscle layer of sigmoid colon, muscle of thigh, myocardium of left ventricle, right auricle of heart, right ventricle, saphenous vein, seminal vesicula, Skeletal muscle tissue of rectus abdominis, sternocleidomastoid muscle, tail of embryo, temporal muscle, triceps brachii muscle

RNA expression pattern · 20

related to External links · 9

TPM1 → COPaKB Archived, Familial Hypertrophic Cardiomyopathy OverviewOverview, Mass, P09493, PDB, PDBe-KB, Tropomyosin, UniProt, Wayback MachineGeneReviews/NIH/NCBI/UW

related to Structure · 6

TPM1 → Human, In, It, Tm, TPM2, TPM3

related to Clinical Significance · 4

TPM1 → HCM, LVNC, Mutations, N-terminal

Band · 2

TPM1 → 15q22.2, 9 C|9 36.27 cM

Chr. · 2

TPM1 → Chromosome 15 (human), Chromosome 9 (mouse)

End · 2

TPM1 → 63,071,915 bp, 66,956,688 bp

Aliases · 1

TPM1 → TPM1, C15orf13, CMD1Y, CMH3, HTM-alpha, LVNC9, TMSA, HEL-S-265, tropomyosin 1 (alpha), tropomyosin 1

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

actin tm human gene bp tropomyosin chr band protein muscle chromosome 15 myosin binding location state end cytoskeleton mouse cardiac

TPM1 relationships Subject–Predicate–Object triples

TTTA extracted 121 structured relationships around TPM1. Examples in this analysis include TPM1 → Aliases → TPM1, C15orf13, CMD1Y, CMH3, HTM-alpha, LVNC9, TMSA, HEL-S-265, tropomyosin 1 (alpha), tropomyosin 1 and TPM1 → Band → 15q22.2. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
TPM1	Aliases	TPM1, C15orf13, CMD1Y, CMH3, HTM-alpha, LVNC9, TMSA, HEL-S-265, tropomyosin 1 (alpha), tropomyosin 1	1.00	infobox
TPM1	Band	15q22.2	1.00	infobox
TPM1	Band	9 C\|9 36.27 cM	1.00	infobox
TPM1	Bgee	myocardium of left ventricle	1.00	infobox
TPM1	Bgee	right ventricle	1.00	infobox
TPM1	Bgee	atrium	1.00	infobox
TPM1	Bgee	right auricle of heart	1.00	infobox
TPM1	Bgee	seminal vesicula	1.00	infobox
TPM1	Bgee	apex of heart	1.00	infobox
TPM1	Bgee	cardiac muscle tissue of right atrium	1.00	infobox
TPM1	Bgee	Skeletal muscle tissue of rectus abdominis	1.00	infobox
TPM1	Bgee	saphenous vein	1.00	infobox
TPM1	Bgee	muscle layer of sigmoid colon	1.00	infobox
TPM1	Bgee	ankle	1.00	infobox
TPM1	Bgee	aortic valve	1.00	infobox
TPM1	Bgee	medial head of gastrocnemius muscle	1.00	infobox
TPM1	Bgee	tail of embryo	1.00	infobox
TPM1	Bgee	ascending aorta	1.00	infobox
TPM1	Bgee	masseter muscle	1.00	infobox
TPM1	Bgee	muscle of thigh	1.00	infobox
TPM1	Bgee	triceps brachii muscle	1.00	infobox
TPM1	Bgee	temporal muscle	1.00	infobox
TPM1	Bgee	sternocleidomastoid muscle	1.00	infobox
TPM1	BioGPS	More reference expression data	1.00	infobox
TPM1	Chr.	Chromosome 15 (human)	1.00	infobox
TPM1	Chr.	Chromosome 9 (mouse)	1.00	infobox
TPM1	Databases	NCBI: entry; OMA: entry	1.00	infobox
TPM1	End	63,071,915 bp	1.00	infobox
TPM1	End	66,956,688 bp	1.00	infobox
TPM1	Ensembl	ENSG00000140416	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around TPM1 bring nearby vocabulary together. In this analysis, examples include Tropomyosin, Human and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

TPM1
- Tropomyosin
- Human
- Gene
- Entry
- Function
- Ncbi
- P09493
- Uniprot
- Location
- Chromosome
- Bp
- Chr
tpm1
- Tropomyosin
- Human
- Gene
- Entry
- Function
- Ncbi
- P09493
- Uniprot
- Location
- Chromosome
- Bp
- Chr
protein
- Muscle
- Tpm1
- Gene
- Tropomyosin
- Human
- Cytoskeleton
- Entry
- Function
- Mouse
- Muscles
- Ncbi
- P09493
gene
- Tropomyosin
- Location
- Chromosome
- Bp
- Chr
- Cytoskeleton
- Function
- Mouse
- Smooth
- Tpm1
- End
- Human
actin
- Tm
- Binding
- Myosin
- Muscle
- Molecules
- State
- End
- Protein
- Cytoskeleton
- Entry
- Function
- Mouse
function
- Location
- Chromosome
- Bp
- Chr
- Gene
- Tropomyosin
- Entry
- Mouse
- Ncbi
- P09493
- Smooth
- Tpm1
myosin
- State
- Tm

Connections between topic areas Semantic bridges

For TPM1, one of the stronger structural bridges in this analysis connects TPM1 with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

TPM1 — Structure · splits 12 ⟂ 6

TPM1 — Function · splits 14 ⟂ 4

TPM1 — Clinical Significance · splits 14 ⟂ 4

TPM1 — Overview · splits 15 ⟂ 3

Map overview Semantic statistics

TPM1

Nodes18

Edges17

Triples121

Avg. degree1.89

Density0.111111

Components1

Source & methodology

TTTA analyzes the structure around TPM1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure, Function & Clinical Significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — TPM1 · EN edition · Analysis: TopicsToTalkAbout