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Voltage-dependent anion-selective channel 1 (VDAC-1) is a beta barrel protein that in humans is encoded by the VDAC1 gene located on chromosome 5. It forms an ion channel in the outer mitochondrial membrane (OMM) and also the outer cell membrane. In the OMM, it allows ATP to diffuse out of the mitochondria into the cytoplasm. In the cell membrane, it is…
Interactions, Clinical significance & Structure
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channel cell pore mitochondrial atp also ion protein transport calcium within membrane function voltage shown anion metabolism apoptosis expression proteins
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| VDAC1 | Aliases | VDAC1, PORIN, VDAC-1, voltage dependent anion channel 1 | 1.00 | infobox |
| VDAC1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2JK4, 2K4T | 1.00 | infobox |
| VDAC1 | Band | 11 B1.3|11 31.86 cM | 1.00 | infobox |
| VDAC1 | Bgee | biceps brachii | 1.00 | infobox |
| VDAC1 | Bgee | Skeletal muscle tissue of biceps brachii | 1.00 | infobox |
| VDAC1 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| VDAC1 | Bgee | muscle of thigh | 1.00 | infobox |
| VDAC1 | Bgee | Skeletal muscle tissue of rectus abdominis | 1.00 | infobox |
| VDAC1 | Bgee | jejunal mucosa | 1.00 | infobox |
| VDAC1 | Bgee | vastus lateralis muscle | 1.00 | infobox |
| VDAC1 | Bgee | right ventricle | 1.00 | infobox |
| VDAC1 | Bgee | left ventricle | 1.00 | infobox |
| VDAC1 | Bgee | glutes | 1.00 | infobox |
| VDAC1 | Bgee | aortic valve | 1.00 | infobox |
| VDAC1 | Bgee | ascending aorta | 1.00 | infobox |
| VDAC1 | Bgee | renal corpuscle | 1.00 | infobox |
| VDAC1 | Bgee | ankle | 1.00 | infobox |
| VDAC1 | Bgee | temporal muscle | 1.00 | infobox |
| VDAC1 | Bgee | thoracic diaphragm | 1.00 | infobox |
| VDAC1 | Bgee | condyle | 1.00 | infobox |
| VDAC1 | Bgee | sternocleidomastoid muscle | 1.00 | infobox |
| VDAC1 | Bgee | pineal gland | 1.00 | infobox |
| VDAC1 | BioGPS | More reference expression data | 1.00 | infobox |
| VDAC1 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| VDAC1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| VDAC1 | End | 52,389,397 bp | 1.00 | infobox |
| VDAC1 | Ensembl | ENSG00000213585 | 1.00 | infobox |
| VDAC1 | Entrez | 7416 | 1.00 | infobox |
| VDAC1 | External IDs | OMIM: 604492; MGI: 106919; GeneCards: VDAC1 | 1.00 | infobox |
| VDAC1 | Gene location (Mouse) | Gene location (Mouse)Chr.Chromosome 11 (mouse)Band11 B1.3|11 31.86 cMStart52,360,860 bpEnd52,389,397 bp | 1.00 | infobox |
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