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Syndecan-4

Syndecan-4 is a protein that in humans is encoded by the SDC4 gene. Syndecan-4 is one of the four vertebrate syndecans and has a molecular weight of ~20 kDa.

Clinical significance, Function & Structure

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Aliases
SDC4, SYND4, syndecan 4
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EJP, 1EJQ, 1OBY, 1YBO
Band
20q13.12 · 2 H3|2 85.16 cM
Bgee
olfactory zone of nasal mucosa · nasal epithelium · cartilage tissue · beta cell · epithelium of bronchus
BioGPS
More reference expression data
Chr.
Chromosome 20 (human) · Chromosome 2 (mouse)

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Syndecan-4

Nodes23
Edges22
Triples116
Avg. degree1.91
Density0.086957
Components1

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Syndecan-4

Top relations

Gene ontology · 35
Syndecan-4 → cell migration, cell surface, costamere, extracellular exosome, extracellular region, fibronectin binding, focal adhesion, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, Golgi lumen, identical protein binding, inner ear receptor cell stereocilium organization, integral component of membrane, integral component of plasma membrane, leukocyte migration, lysosomal lumen, membrane, membrane raft, negative regulation of T cell proliferation
Bgee · 20
Syndecan-4 → aortic valve, ascending aorta, beta cell, blastocyst, bronchial epithelial cell, cartilage tissue, ciliary body, epithelium of bronchus, external globus pallidus, gallbladder, human kidney, lacrimal gland, left lobe of liver, nasal epithelium, olfactory zone of nasal mucosa, skin of abdomen, skin of leg, superior surface of tongue, utricle, vestibular membrane of cochlear duct
RNA expression pattern · 20
Syndecan-4 → aortic valve, ascending aorta, beta cell, blastocyst, bronchial epithelial cell, cartilage tissue, ciliary body, epithelium of bronchus, external globus pallidus, gallbladder, human kidney, lacrimal gland, left lobe of liver, nasal epithelium, olfactory zone of nasal mucosa, skin of abdomen, skin of leg, superior surface of tongue, utricle, vestibular membrane of cochlear duct
related to External links · 5
Syndecan-4 → Overview, P31431, PDB, PDBe-KB, UniProt
related to Endometriosis · 4
Syndecan-4 → Activating, ATF2, GTPase Rac1, MMP3
related to Function · 4
Syndecan-4 → It, PIP2, PKC, The
related to Osteoarthritis · 3
Syndecan-4 → OA, See Sindecán-4, Spanish Wikipedia
Band · 2
Syndecan-4 → 2 H3|2 85.16 cM, 20q13.12
Chr. · 2
Syndecan-4 → Chromosome 2 (mouse), Chromosome 20 (human)
End · 2
Syndecan-4 → 164,285,807 bp, 45,348,424 bp

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Important terminology

syndecans 20 gene bp cell chr human band chromosome protein sdc4 signaling also growth syndecan function found external mouse receptor

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Syndecan-4AliasesSDC4, SYND4, syndecan 41.00infobox
Syndecan-4Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EJP, 1EJQ, 1OBY, 1YBO1.00infobox
Syndecan-4Band20q13.121.00infobox
Syndecan-4Band2 H3|2 85.16 cM1.00infobox
Syndecan-4Bgeeolfactory zone of nasal mucosa1.00infobox
Syndecan-4Bgeenasal epithelium1.00infobox
Syndecan-4Bgeecartilage tissue1.00infobox
Syndecan-4Bgeebeta cell1.00infobox
Syndecan-4Bgeeepithelium of bronchus1.00infobox
Syndecan-4Bgeebronchial epithelial cell1.00infobox
Syndecan-4Bgeeskin of abdomen1.00infobox
Syndecan-4Bgeeskin of leg1.00infobox
Syndecan-4Bgeeexternal globus pallidus1.00infobox
Syndecan-4Bgeehuman kidney1.00infobox
Syndecan-4Bgeevestibular membrane of cochlear duct1.00infobox
Syndecan-4Bgeegallbladder1.00infobox
Syndecan-4Bgeelacrimal gland1.00infobox
Syndecan-4Bgeeblastocyst1.00infobox
Syndecan-4Bgeeciliary body1.00infobox
Syndecan-4Bgeeutricle1.00infobox
Syndecan-4Bgeeascending aorta1.00infobox
Syndecan-4Bgeeleft lobe of liver1.00infobox
Syndecan-4Bgeesuperior surface of tongue1.00infobox
Syndecan-4Bgeeaortic valve1.00infobox
Syndecan-4BioGPSMore reference expression data1.00infobox
Syndecan-4Chr.Chromosome 20 (human)1.00infobox
Syndecan-4Chr.Chromosome 2 (mouse)1.00infobox
Syndecan-4DatabasesNCBI: entry; OMA: entry1.00infobox
Syndecan-4End45,348,424 bp1.00infobox
Syndecan-4End164,285,807 bp1.00infobox

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