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Ion channel

Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore. Their functions include establishing a resting membrane potential, shaping action potentials and other electrical signals by gating the flow of ions across the cell membrane, controlling the flow of ions across secretory and epithelial cells, and regulating…

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Overview

Basic features

Biological role

Diversity

Detailed structure

Pharmacology

Diseases

History

Culture

Ion channels and stochastic processes

Advanced semantic analysis

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Map overview Semantic statistics

Ion channel

Nodes214
Edges213
Triples194
Avg. degree1.99
Density0.009346
Components1

How this topic connects Entity context

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Ion channel

Top relations

related to Classification by type of ions · 33
Ion channel → Bestrophins, BKCa, Ca2, Calcium, Calcium-activated, CaVs, CFTRs, Chloride, ClCs, CLICs, ENaCs, Epithelial, Goldman-Hodgkin-Katz, Inward-rectifier, It, Kirs, Kvs, MaxiK, Most, Na
related to Diseases · 28
Ion channel → Brugada, CFTR, Channelopathies, ClC-3, Cystic, EA, Episodic, Equine, Familial, FHM, GEFS, Generalized, Genetic, HyperPP, In Glioblastoma, IV, Mucolipidosis, NMDA, PAM, Paramyotonia
related to Classification by cellular localization · 25
Ion channel → BK, Calcium, Cav, Chloride, ClC, CLIC4, CLIC5, Examples, Golgi, IK, Intracellular, Ion, IP3RMitochondrial, KATP, Kv, Kv7, Nav, On, Orai, Plasma
related to history · 19
Ion channel → Alan Hodgkin, Andrew Huxley, Baker's, Bernard Katz, Bert Sakmann, British, Chemistry, Cole, Erwin Neher, Hundreds, In, It, Nobel Prize, Nobel Prize-winning, Ricardo Miledi, Roderick MacKinnon, The, The Nobel Prize, They
related to Detailed structure · 15
Ion channel → Bertil Hille, Channels, Chemistry, Cl, Clay Armstrong, KcsA, Mackinnon, Na, Nobel Prize, On, Roderick MacKinnon, The, This, Two, X-ray
related to External links · 14
Ion channel → Archived, Basic, Clinical Pharmacology, International Union, Ion Channels, IUPHAR Database, Medicine Medical Subject Headings, MeSH, National Library, Receptors, The Weiss Lab, TRIP Database, TRP, Voltage-Gated Ion Channels
related to Other classifications · 14
Ion channel → Ca2, Drosophila, Some, Some TRP, These, This, Transient, TRP, TRPA, TRPC, TRPM, TRPML, TRPP, TRPV
related to Ion channel blockers · 13
Ion channel → Conotoxin, Dendrotoxin, Eastern Indian, Heteropoda, Heteropodatoxin, Hottentotta, Iberiotoxin, It, Lidocaine, Saxitoxin, Some, Tetrodotoxin, TTX
related to Ion channels and stochastic processes · 6
Ion channel → In, Ion, Markov, Stochastic, The, We
related to Ion channel activators · 5
Ion channel → Bay K8644Chloride, Calcium, DDT, Several, These

Important terminology Word statistics

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Important terminology

channels ion channel potassium membrane family subunits voltage-gated sodium open citation needed members ions pore also two cells intracellular known

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
pacemaker activity in the heartinstance ofThey are involved in important physiological processes0.80text
insulin releaseinstance ofThey are involved in important physiological processes0.80text
and potassium uptake in glial cellsinstance ofThey are involved in important physiological processes0.80text
exercise.Familial hemiplegic migraineinstance ofor heavy exertion0.80text
Ion channelrelated to Basic featuresThere0.60section
Ion channelrelated to Basic featuresThe0.60section
Ion channelrelated to Basic featuresIons0.60section
Ion channelrelated to Basic featuresATP0.60section
Ion channelrelated to Biological roleBecause0.60section
Ion channelrelated to Biological roleIndeed0.60section
Ion channelrelated to Biological roleIn0.60section
Ion channelrelated to Biological roleT-cell0.60section

Related concept clusters Concept neighborhoods

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