Troponin T, cardiac muscle

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Clinical significance

Hypertrophic cardiomyopathy Restrictive Dilated cardiomyopathy Alternative splicing Hypertrophy

14 related topics

Structure

TnI TnC Actin Tm

4 related topics

Function

Myosin Cooperativity

2 related topics

Overview

Protein Gene Tropomyosin Troponin Methionine

6 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: TNNT2, CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT, troponin T2, cardiac type
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1J1D, 1J1E, 4Y99
Band: 1q32.1 · 1 E4|1 59.32 cM
Bgee: apex of heart · right auricle of heart · left ventricle · sural nerve · right frontal lobe
BioGPS: More reference expression data
Chr.: Chromosome 1 (human) · Chromosome 1 (mouse)

Topics to explore

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Overview

Structure

TnI TNNI3
TnC TNNC1
Actin ACTC1
Tm TPM1

Function

Myosin MYH7
Cooperativity Cooperative binding

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes31

Edges30

Triples101

Avg. degree1.94

Density0.064516

Components1

How this topic connects Entity context

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Troponin T, cardiac muscle

Top relations

Gene ontology · 30

Troponin T, cardiac muscle → actin binding, actin crosslink formation, ATPase activity, calcium ion binding, calcium-dependent ATPase activity, cardiac muscle contraction, cardiac myofibril, cardiac Troponin complex, cytosol, muscle contraction, muscle filament sliding, myofibril, negative regulation of ATP-dependent activity, positive regulation of ATP-dependent activity, protein binding, protein heterooligomerization, protein-macromolecule adaptor activity, regulation of heart contraction, regulation of muscle contraction, regulation of muscle filament sliding speed

Bgee · 19

Troponin T, cardiac muscle → anterior cingulate cortex, aortic valve, apex of heart, atrioventricular valve, atrium, Brodmann area 9, cardiac muscle tissue of left ventricle, cardiac muscles, endocardial cushion, interventricular septum, left ventricle, myocardium of ventricle, right auricle of heart, right frontal lobe, right lung, right ventricle, skin of abdomen, skin of leg, sural nerve

RNA expression pattern · 19

related to External links · 10

Troponin T, cardiac muscle → COPaKB Archived, Familial Hypertrophic Cardiomyopathy OverviewOverview, Mass, P45379, PDB, PDBe-KB, TNNT2, Troponin, UniProt, Wayback MachineGeneReviews/NIH/NCBI/UW

Band · 2

Troponin T, cardiac muscle → 1 E4|1 59.32 cM, 1q32.1

Chr. · 2

Troponin T, cardiac muscle → Chromosome 1 (human), Chromosome 1 (mouse)

End · 2

Troponin T, cardiac muscle → 135,779,998 bp, 201,377,764 bp

Aliases · 1

Troponin T, cardiac muscle → TNNT2, CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT, troponin T2, cardiac type

Available structures · 1

Troponin T, cardiac muscle → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1J1D, 1J1E, 4Y99

BioGPS · 1

Troponin T, cardiac muscle → More reference expression data

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cardiac muscle troponin gene ctnt tnnt2 tnt human n-terminal protein region bp phosphorylation mutations skeletal complex thin filament myosin calcium

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Troponin T, cardiac muscle	Aliases	TNNT2, CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT, troponin T2, cardiac type	1.00	infobox
Troponin T, cardiac muscle	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1J1D, 1J1E, 4Y99	1.00	infobox
Troponin T, cardiac muscle	Band	1q32.1	1.00	infobox
Troponin T, cardiac muscle	Band	1 E4\|1 59.32 cM	1.00	infobox
Troponin T, cardiac muscle	Bgee	apex of heart	1.00	infobox
Troponin T, cardiac muscle	Bgee	right auricle of heart	1.00	infobox
Troponin T, cardiac muscle	Bgee	left ventricle	1.00	infobox
Troponin T, cardiac muscle	Bgee	sural nerve	1.00	infobox
Troponin T, cardiac muscle	Bgee	right frontal lobe	1.00	infobox
Troponin T, cardiac muscle	Bgee	skin of leg	1.00	infobox
Troponin T, cardiac muscle	Bgee	Brodmann area 9	1.00	infobox
Troponin T, cardiac muscle	Bgee	skin of abdomen	1.00	infobox
Troponin T, cardiac muscle	Bgee	anterior cingulate cortex	1.00	infobox
Troponin T, cardiac muscle	Bgee	right lung	1.00	infobox
Troponin T, cardiac muscle	Bgee	atrioventricular valve	1.00	infobox
Troponin T, cardiac muscle	Bgee	atrium	1.00	infobox
Troponin T, cardiac muscle	Bgee	myocardium of ventricle	1.00	infobox
Troponin T, cardiac muscle	Bgee	aortic valve	1.00	infobox
Troponin T, cardiac muscle	Bgee	cardiac muscles	1.00	infobox
Troponin T, cardiac muscle	Bgee	interventricular septum	1.00	infobox
Troponin T, cardiac muscle	Bgee	cardiac muscle tissue of left ventricle	1.00	infobox
Troponin T, cardiac muscle	Bgee	right ventricle	1.00	infobox
Troponin T, cardiac muscle	Bgee	endocardial cushion	1.00	infobox
Troponin T, cardiac muscle	BioGPS	More reference expression data	1.00	infobox
Troponin T, cardiac muscle	Chr.	Chromosome 1 (human)	1.00	infobox
Troponin T, cardiac muscle	Chr.	Chromosome 1 (mouse)	1.00	infobox
Troponin T, cardiac muscle	Databases	NCBI: entry; OMA: entry	1.00	infobox
Troponin T, cardiac muscle	End	201,377,764 bp	1.00	infobox
Troponin T, cardiac muscle	End	135,779,998 bp	1.00	infobox
Troponin T, cardiac muscle	Ensembl	ENSG00000118194	1.00	infobox

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