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Iguratimod: Art & Overview

Iguratimod is an anti-inflammatory small molecule drug used for the treatment of rheumatoid arthritis, together with methotrexate in Japan and China. As of 2015, the biological target was not known, but it prevents NF-κB activation and subsequently selectively inhibits COX-2 and several inflammatory cytokines.

Language: English [EN]
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Iguratimod topic overview

The analysis highlights Art and Overview as prominent areas in the source structure around Iguratimod.

Related topics
11
Source areas
1
Connected nodes
12
Extracted relationships
14
Concept neighborhoods
11
Bridge connections
12

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 11 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
None
CAS Number
123663-49-0
ChEMBL
ChEMBL2107455
ChemSpider
110694
CompTox Dashboard (EPA)
DTXSID0048971

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Iguratimod connects Entity context

The extracted context around Iguratimod shows recurring relationship patterns in the source. For example, Iguratimod → Interactive image Another extracted example is Iguratimod → None. Use these groups to spot repeated connection types before inspecting the individual relationships.

Iguratimod

Top relations

3D model (JSmol) · 1
Iguratimod → Interactive image
ATC code · 1
Iguratimod → None
CAS Number · 1
Iguratimod → 123663-49-0
ChEMBL · 1
Iguratimod → ChEMBL2107455
ChemSpider · 1
Iguratimod → 110694
CompTox Dashboard (EPA) · 1
Iguratimod → DTXSID0048971
ECHA InfoCard · 1
Iguratimod → 100.236.037
Formula · 1
Iguratimod → C17H14N2O6S
Molar mass · 1
Iguratimod → 374.37 g·mol−1
Other names · 1
Iguratimod → T-614

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

japan china approval 2011 t-614 names careram kolbet anti-inflammatory methotrexate nf-κb cox-2 cytokines chromone eisai small molecule drug used treatment

Iguratimod relationships Subject–Predicate–Object triples

TTTA extracted 14 structured relationships around Iguratimod. Examples in this analysis include Iguratimod → 3D model (JSmol) → Interactive image and Iguratimod → ATC code → None. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Iguratimod3D model (JSmol)Interactive image1.00infobox
IguratimodATC codeNone1.00infobox
IguratimodCAS Number123663-49-01.00infobox
IguratimodChEMBLChEMBL21074551.00infobox
IguratimodChemSpider1106941.00infobox
IguratimodCompTox Dashboard (EPA)DTXSID00489711.00infobox
IguratimodECHA InfoCard100.236.0371.00infobox
IguratimodFormulaC17H14N2O6S1.00infobox
IguratimodMolar mass374.37 g·mol−11.00infobox
IguratimodOther namesT-6141.00infobox
IguratimodPubChem CID1242461.00infobox
IguratimodTrade namesCareram; Kolbet1.00infobox
IguratimodUNII4IHY34Y2NV1.00infobox
Iguratimodis aanti-inflammatory small molecule drug used for the treatment of rheumatoid arthritis0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Iguratimod bring nearby vocabulary together. In this analysis, examples include Arthritis, Drug and Methotrexate. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Iguratimod
    • Arthritis
    • Drug
    • Methotrexate
    • Molecule
    • Rheumatoid
    • Small
    • Together
    • Treatment
    • Used
    • Careram
    • China
    • Kolbet
  • iguratimod
    • Arthritis
    • Drug
    • Methotrexate
    • Molecule
    • Rheumatoid
    • Small
    • Together
    • Treatment
    • Used
    • Careram
    • China
    • Kolbet
  • biological target
    • Activation
    • Biological
    • Cox-2
    • Cytokines
    • Inflammatory
    • Inhibits
    • Known
    • Nf-κb
    • Prevents
    • Selectively
    • Several
    • Subsequently
  • anti-inflammatory
    • Arthritis
    • Drug
    • Methotrexate
    • Molecule
    • Rheumatoid
    • Small
    • Together
    • Treatment
    • Used
    • China
    • Iguratimod
    • Japan
  • rheumatoid arthritis
    • Drug
    • Methotrexate
    • Molecule
    • Rheumatoid
    • Small
    • Together
    • Treatment
    • Used
    • China
    • Iguratimod
    • Japan
  • cox-2
    • Cytokines
    • Inflammatory
    • Inhibits
    • Known
    • Nf-κb
    • Prevents
    • Selectively
    • Several
    • Subsequently
    • Target
  • nf-κb
    • Cox-2
    • Cytokines
    • Inflammatory
    • Inhibits
    • Prevents
    • Selectively
    • Several
    • Subsequently
    • Target
  • cytokines
    • Inflammatory
    • Inhibits
    • Known
    • Nf-κb
    • Prevents
    • Selectively
    • Several
    • Subsequently
    • Target

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the Iguratimod map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

Iguratimod

Nodes13
Edges12
Triples14
Avg. degree1.85
Density0.153846
Components1

Source & methodology

TTTA analyzes the structure around Iguratimod to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Iguratimod · EN edition · Analysis: TopicsToTalkAbout

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