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Iguratimod

Iguratimod is an anti-inflammatory small molecule drug used for the treatment of rheumatoid arthritis, together with methotrexate in Japan and China. As of 2015, the biological target was not known, but it prevents NF-κB activation and subsequently selectively inhibits COX-2 and several inflammatory cytokines.

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Key facts & relationships

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3D model (JSmol)
Interactive image
ATC code
None
CAS Number
123663-49-0
ChEMBL
ChEMBL2107455
ChemSpider
110694
CompTox Dashboard (EPA)
DTXSID0048971

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Overview

Advanced semantic analysis

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Map overview Semantic statistics

Iguratimod

Nodes13
Edges12
Triples14
Avg. degree1.85
Density0.153846
Components1

How this topic connects Entity context

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Iguratimod

Top relations

3D model (JSmol) · 1
Iguratimod → Interactive image
ATC code · 1
Iguratimod → None
CAS Number · 1
Iguratimod → 123663-49-0
ChEMBL · 1
Iguratimod → ChEMBL2107455
ChemSpider · 1
Iguratimod → 110694
CompTox Dashboard (EPA) · 1
Iguratimod → DTXSID0048971
ECHA InfoCard · 1
Iguratimod → 100.236.037
Formula · 1
Iguratimod → C17H14N2O6S
Molar mass · 1
Iguratimod → 374.37 g·mol−1
Other names · 1
Iguratimod → T-614

Important terminology Word statistics

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Important terminology

japan china approval 2011 t-614 names careram kolbet anti-inflammatory methotrexate nf-κb cox-2 cytokines chromone eisai small molecule drug used treatment

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Iguratimod3D model (JSmol)Interactive image1.00infobox
IguratimodATC codeNone1.00infobox
IguratimodCAS Number123663-49-01.00infobox
IguratimodChEMBLChEMBL21074551.00infobox
IguratimodChemSpider1106941.00infobox
IguratimodCompTox Dashboard (EPA)DTXSID00489711.00infobox
IguratimodECHA InfoCard100.236.0371.00infobox
IguratimodFormulaC17H14N2O6S1.00infobox
IguratimodMolar mass374.37 g·mol−11.00infobox
IguratimodOther namesT-6141.00infobox
IguratimodPubChem CID1242461.00infobox
IguratimodTrade namesCareram; Kolbet1.00infobox
IguratimodUNII4IHY34Y2NV1.00infobox
Iguratimodis aanti-inflammatory small molecule drug used for the treatment of rheumatoid arthritis0.90text

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