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1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 is an enzyme that in humans is encoded by the PLCG2 gene.
The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around PLCG2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PLCG2 shows recurring relationship patterns in the source. For example, PLCG2 → activation of store-operated calcium channel activity, B cell differentiation, B cell receptor signaling pathway, calcium-mediated signaling, cytosol, extracellular exosome, Fc-epsilon receptor signaling pathway, Fc-gamma receptor signaling pathway involved in phagocytosis, follicular B cell differentiation, hydrolase activity, inositol phosphate metabolic process, inositol trisphosphate biosynthetic process, intracellular signal transduction, lipid catabolic process, lipid metabolism, negative regulation of programmed cell death, phosphatidylinositol biosynthetic process, phosphatidylinositol phospholipase C activity, phosphatidylinositol-mediated signaling, phospholipase C activity Another extracted example is PLCG2 → appendix, basilar part of occipital bone, blood, bone marrow, bone marrow cell, endothelial cell, epithelium of nasopharynx, external carotid artery, glomerulus, granulocyte, internal carotid artery, kidney tubule, mesenteric lymph nodes, metanephric glomerulus, sphenoid bone, spleen, tibiofemoral joint. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp chr human band gene phospholipase chromosome 16 location enzymes enzyme mouse function omim external search activity 962 685 end
TTTA extracted 99 structured relationships around PLCG2. Examples in this analysis include PLCG2 → 3.1.4.11 → ↗ and PLCG2 → Aliases → PLCG2, APLAID, FCAS3, PLC-IV, PLC-gamma-2, phospholipase C gamma 2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PLCG2 | 3.1.4.11 | ↗ | 1.00 | infobox |
| PLCG2 | Aliases | PLCG2, APLAID, FCAS3, PLC-IV, PLC-gamma-2, phospholipase C gamma 2 | 1.00 | infobox |
| PLCG2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2K2J, 2W2W, 2W2X | 1.00 | infobox |
| PLCG2 | Band | 16q23.3 | 1.00 | infobox |
| PLCG2 | Band | 8 E1|8 64.26 cM | 1.00 | infobox |
| PLCG2 | Bgee | glomerulus | 1.00 | infobox |
| PLCG2 | Bgee | bone marrow cell | 1.00 | infobox |
| PLCG2 | Bgee | blood | 1.00 | infobox |
| PLCG2 | Bgee | metanephric glomerulus | 1.00 | infobox |
| PLCG2 | Bgee | epithelium of nasopharynx | 1.00 | infobox |
| PLCG2 | Bgee | spleen | 1.00 | infobox |
| PLCG2 | Bgee | granulocyte | 1.00 | infobox |
| PLCG2 | Bgee | endothelial cell | 1.00 | infobox |
| PLCG2 | Bgee | appendix | 1.00 | infobox |
| PLCG2 | Bgee | kidney tubule | 1.00 | infobox |
| PLCG2 | Bgee | basilar part of occipital bone | 1.00 | infobox |
| PLCG2 | Bgee | tibiofemoral joint | 1.00 | infobox |
| PLCG2 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| PLCG2 | Bgee | bone marrow | 1.00 | infobox |
| PLCG2 | Bgee | sphenoid bone | 1.00 | infobox |
| PLCG2 | Bgee | external carotid artery | 1.00 | infobox |
| PLCG2 | Bgee | internal carotid artery | 1.00 | infobox |
| PLCG2 | BioGPS | More reference expression data | 1.00 | infobox |
| PLCG2 | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| PLCG2 | Chr. | Chromosome 8 (mouse) | 1.00 | infobox |
| PLCG2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PLCG2 | End | 81,962,685 bp | 1.00 | infobox |
| PLCG2 | End | 118,361,881 bp | 1.00 | infobox |
| PLCG2 | Ensembl | ENSG00000197943 | 1.00 | infobox |
| PLCG2 | Entrez | 5336 | 1.00 | infobox |
The concept neighborhoods around PLCG2 bring nearby vocabulary together. In this analysis, examples include Omim, Search and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PLCG2, one of the stronger structural bridges in this analysis connects PLCG2 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PLCG2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PLCG2 · EN edition · Analysis: TopicsToTalkAbout